Chemically modified short interfering hybrids (siHYBRIDS): nanoimmunoliposome delivery in vitro and in vivo for RNAi of HER-2. (Q40244901)

18 September 2017

Chemically modified short interfering hybrids (siHYBRIDS): nanoimmunoliposome delivery in vitro and in vivo for RNAi of HER-2. (English)

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18 September 2017

Richard I Hogrefe

1

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18 September 2017

Alexandre V Lebedev

2

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18 September 2017

Gerald Zon

3

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18 September 2017

Kathleen F Pirollo

4

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18 September 2017

Antonina Rait

5

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18 September 2017

Qi Zhou

6

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18 September 2017

Wei Yu

7

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18 September 2017

Esther H Chang

8

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18 September 2017

1 January 2006

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Nucleosides, Nucleotides & Nucleic Acids

18 September 2017

19

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based on heuristic

inferred from page(s)

published in

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18 September 2017

25

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18 September 2017

8

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18 September 2017

889-907

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siRNAs: applications in functional genomics and potential as therapeutics

18 September 2017

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https://api.crossref.org/works/10.1080%2F15257770600793885

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Antisense technologies. Improvement through novel chemical modifications

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Fully 2'-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA.

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Tolerance for mutations and chemical modifications in a siRNA.

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

siRNA function in RNAi: a chemical modification analysis

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

RNA interference in mammalian cells by chemically-modified RNA.

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Hypoxia reduces constitutive and TNF-alpha-induced expression of monocyte chemoattractant protein-1 in human proximal renal tubular cells.

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Molecular requirements for RNA-induced silencing complex assembly in the Drosophila RNA interference pathway.

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

RNA interference (RNA(i)) induction with various types of synthetic oligonucleotide duplexes in cultured human cells.

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Varying the Nucleic Acid Composition of siRNA Molecules Dramatically Varies the Duration and Degree of Gene Silencing

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Expression profiling reveals off-target gene regulation by RNAi

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Novel cationic cardiolipin analogue-based liposome for efficient DNA and small interfering RNA delivery in vitro and in vivo

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Small interfering RNA (siRNA) inhibits the expression of the Her2/neu gene, upregulates HLA class I and induces apoptosis of Her2/neu positive tumor cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

HER-2-targeted antisense oligonucleotide results in sensitization of head and neck cancer cells to chemotherapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

Inhibitory effects of the combination of HER-2 antisense oligonucleotide and chemotherapeutic agents used for the treatment of human breast cancer

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Tumor-targeting nanoimmunoliposome complex for short interfering RNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

Enhanced transfection efficiency of a systemically delivered tumor-targeting immunolipoplex by inclusion of a pH-sensitive histidylated oligolysine peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

Immunohistochemical evaluation of K-ras, p53, and HER-2/neu expression in hyperplastic, dysplastic, and carcinomatous lesions of the pancreas: evidence for multistep carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

Innovative treatments for pancreatic cancer.

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Antitumor activity of HER-2 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

The antiepidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

A sterically stabilized immunolipoplex for systemic administration of a therapeutic gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

Functional siRNAs and miRNAs Exhibit Strand Bias

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

Inhibition of breast and ovarian tumor growth through multiple signaling pathways by using retrovirus-mediated small interfering RNA against Her-2/neu gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

Silencing of the HER2/neu gene by siRNA inhibits proliferation and induces apoptosis in HER2/neu-overexpressing breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770600793885

Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

Fusogenic liposome delivers encapsulated nanoparticles for cytosolic controlled gene release

21 January 2018

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https://api.crossref.org/works/10.1080%2F15257770600793885

10.1080/15257770600793885

21 January 2018

Identifiers

DOI

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18 September 2017

1 reference