The Elephant in the Room: The Role of Microtubules in Cancer (Q38672574)

5 September 2017

1 reference

title

The Elephant in the Room: The Role of Microtubules in Cancer (English)

1 reference

5 September 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28600784%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Patrick Meraldi

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28600784%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Monica Gotta

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28600784%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

language of work or name

English

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publication date

1 January 2017

1 reference

Advances in Experimental Medicine and Biology

5 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28600784%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

1002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28600784%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

93-124

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28600784%20AND%20SRC:MED&resulttype=core&format=json

Dynamic instability of microtubule growth

31 May 2020

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Does aneuploidy cause cancer?

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Losing balance: the origin and impact of aneuploidy in cancer

21 January 2018

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Chromosomal instability and aneuploidy in cancer: from yeast to man

21 January 2018

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Chromosomal instability is a risk factor for poor prognosis of adenocarcinoma of the lung: Fluorescence in situ hybridization analysis of paraffin-embedded tissue from Korean patients

21 January 2018

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Chromosome instability, chromosome transcriptome, and clonal evolution of tumor cell populations

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Chromosomal instability correlates with poor outcome in patients with myelodysplastic syndromes irrespectively of the cytogenetic risk group

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Chromosomal instability confers intrinsic multidrug resistance.

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Chromosomal instability: a composite phenotype that influences sensitivity to chemotherapy

21 January 2018

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Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells

21 January 2018

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Timing of centrosome separation is important for accurate chromosome segregation

21 January 2018

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Examining the link between chromosomal instability and aneuploidy in human cells

21 January 2018

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Merotelic kinetochore attachment: causes and effects.

21 January 2018

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Mechanisms to Avoid and Correct Erroneous Kinetochore-Microtubule Attachments

21 January 2018

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Kinetochore-microtubule interactions: steps towards bi-orientation

21 January 2018

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Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates

21 January 2018

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Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface

21 January 2018

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Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore

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Regulation of kinetochore-microtubule attachments through homeostatic control during mitosis

21 January 2018

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The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling

21 January 2018

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Sensing centromere tension: Aurora B and the regulation of kinetochore function

21 January 2018

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The centromere geometry essential for keeping mitosis error free is controlled by spindle forces

21 January 2018

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Mechanisms of spindle-pole organization are influenced by kinetochore activity in mammalian cells.

21 January 2018

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Kinetochore motors drive congression of peripheral polar chromosomes by overcoming random arm-ejection forces.

21 January 2018

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Spatial Regulation of Kinetochore Microtubule Attachments by Destabilization at Spindle Poles in Meiosis I.

21 January 2018

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Aurora A Kinase Contributes to a Pole-Based Error Correction Pathway.

21 January 2018

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Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation

21 January 2018

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CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity

21 January 2018

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Aurora B kinase controls the targeting of the Astrin-SKAP complex to bioriented kinetochores.

21 January 2018

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MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochore attachment

21 January 2018

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MCAK facilitates chromosome movement by promoting kinetochore microtubule turnover

21 January 2018

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Aurora B regulates MCAK at the mitotic centromere

21 January 2018

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Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity

21 January 2018

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The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint

21 January 2018

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Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

21 January 2018

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The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

21 January 2018

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Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis

21 January 2018

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Correcting improper chromosome-spindle attachments during cell division

21 January 2018

1 reference

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Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections

21 January 2018

1 reference

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DNA-damage response during mitosis induces whole-chromosome missegregation

21 January 2018

1 reference

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Mad2 overexpression promotes aneuploidy and tumorigenesis in mice

21 January 2018

1 reference

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CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

21 January 2018

1 reference

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The putative oncogene CEP72 inhibits the mitotic function of BRCA1 and induces chromosomal instability.

21 January 2018

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CHK2 kinase: cancer susceptibility and cancer therapy - two sides of the same coin?

21 January 2018

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Aurora-A: the maker and breaker of spindle poles

21 January 2018

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Chk1 and Chk2 kinases in checkpoint control and cancer

21 January 2018

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Shared and separate functions of polo-like kinases and aurora kinases in cancer

21 January 2018

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Cancer Incidence in BRCA1 mutation carriers

21 January 2018

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Dual pathway spindle assembly increases both the speed and the fidelity of mitosis

21 January 2018

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Kinetochores accelerate centrosome separation to ensure faithful chromosome segregation.

21 January 2018

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Chromosome malorientations after meiosis II arrest cause nondisjunction

21 January 2018

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Chromosome missegregation in human cells arises through specific types of kinetochore-microtubule attachment errors

21 January 2018

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Aneuploidy in mitosis of PtK1 cells is generated by random loss and nondisjunction of individual chromosomes.

21 January 2018

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DNA breaks and chromosome pulverization from errors in mitosis

21 January 2018

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Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins

21 January 2018

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Genetic instability: tipping the balance

21 January 2018

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Proliferation of aneuploid human cells is limited by a p53-dependent mechanism.

21 January 2018

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Tetraploidy, aneuploidy and cancer

21 January 2018

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Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis

21 January 2018

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MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

21 January 2018

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Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation

21 January 2018

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Overexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation

21 January 2018

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Aneuploidy acts both oncogenically and as a tumor suppressor

21 January 2018

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Living in CIN: Mitotic Infidelity and Its Consequences for Tumor Promotion and Suppression

21 January 2018

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Aneuploidy and chromosomal instability in cancer: a jackpot to chaos

21 January 2018

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Effects of aneuploidy on cellular physiology and cell division in haploid yeast

21 January 2018

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Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells

21 January 2018

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Single-chromosome Gains Commonly Function as Tumor Suppressors.

21 January 2018

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Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

21 January 2018

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Mitotic chromosomal instability and cancer: mouse modelling of the human disease.

21 January 2018

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Clinical and genetic heterogeneity in patients with mosaic variegated aneuploidy: delineation of clinical subtypes.

21 January 2018

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Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B.

21 January 2018

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Mutations in CEP57 cause mosaic variegated aneuploidy syndrome.

21 January 2018

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Molecular causes for BUBR1 dysfunction in the human cancer predisposition syndrome mosaic variegated aneuploidy.

21 January 2018

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Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied

21 January 2018

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Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.

21 January 2018

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Polo-like kinase-1 regulates kinetochore-microtubule dynamics and spindle checkpoint silencing

21 January 2018

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Aurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forces

21 January 2018

1 reference

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Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis

21 January 2018

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Aurora A phosphorylates MCAK to control ran-dependent spindle bipolarity

21 January 2018

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Checkpoint-independent stabilization of kinetochore-microtubule attachments by Mad2 in human cells

21 January 2018

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Clinicopathological and biological significance of mitotic centromere-associated kinesin overexpression in human gastric cancer

21 January 2018

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Histopathologic determinants of regional lymph node metastasis in early colorectal cancer

21 January 2018

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Overexpression of mitotic centromere-associated Kinesin stimulates microtubule detachment and confers resistance to paclitaxel

21 January 2018

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Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance

21 January 2018

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Cyclins and cell cycle control in cancer and disease

21 January 2018

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Roles of Aurora kinases in mitosis and tumorigenesis.

21 January 2018

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Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state.

21 January 2018

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Cell cycle kinases in cancer

21 January 2018

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Aurora B: a new prognostic marker and therapeutic target in cancer

21 January 2018

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Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivo

21 January 2018

1 reference

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Knockdown of HURP inhibits the proliferation of hepacellular carcinoma cells via downregulation of gankyrin and accumulation of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Kinesin 18A expression: clinical relevance to colorectal cancer progression.

21 January 2018

1 reference

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Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Kif18A is involved in human breast carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

The MAP2/Tau family of microtubule-associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Interactions between CLIP-170, tubulin, and microtubules: implications for the mechanism of Clip-170 plus-end tracking behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Cytoplasmic linker proteins promote microtubule rescue in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Survivin modulates microtubule dynamics and nucleation throughout the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Mdp3 is a novel microtubule-binding protein that regulates microtubule assembly and stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

EB1-microtubule interactions in Xenopus egg extracts: role of EB1 in microtubule stabilization and mechanisms of targeting to microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Tau stabilizes microtubules by binding at the interface between tubulin heterodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Microtubules and microtubule-associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Tau and neurodegenerative disease: the story so far.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Microtubule-associated protein tau: a marker of paclitaxel sensitivity in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Cell cycle effects and induction of premitotic apoptosis by irofulven in synchronized cancer cells

21 January 2018

1 reference

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Microtubule-associated protein 2, a marker of neuronal differentiation, induces mitotic defects, inhibits growth of melanoma cells, and predicts metastatic potential of cutaneous melanoma

21 January 2018

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Microtubule-associated protein Mdp3 promotes breast cancer growth and metastasis

21 January 2018

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Dynamic localization of CLIP-170 to microtubule plus ends is coupled to microtubule assembly

21 January 2018

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Restin in Hodgkin's disease and anaplastic large cell lymphoma

21 January 2018

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Microtubule-binding protein CLIP-170 is a mediator of paclitaxel sensitivity

21 January 2018

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Regulation of tumor angiogenesis by the microtubule-binding protein CLIP-170.

21 January 2018

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EB1 regulates microtubule dynamics and tubulin sheet closure in vitro.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

End Binding 1 (EB1) overexpression in oral lesions and cancer: A biomarker of tumor progression and poor prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Rac1 and Stathmin but Not EB1 Are Required for Invasion of Breast Cancer Cells in Response to IGF-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Proteomic identification of differentially-expressed genes in human gastric carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Proteomic profiling reveals the prognostic value of adenomatous polyposis coli-end-binding protein 1 in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

End-binding protein 1 (EB1) up-regulation is an early event in colorectal carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Survivin, versatile modulation of cell division and apoptosis in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Characterization of the cDNA and pattern of expression of a new gene over-expressed in human hepatomas and colonic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

XMAP215 is a processive microtubule polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Clathrin recruits phosphorylated TACC3 to spindle poles for bipolar spindle assembly and chromosome alignment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Coordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

The role of clathrin in mitotic spindle organisation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Role of centrosomal adaptor proteins of the TACC family in the regulation of microtubule dynamics during mitotic cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Inhibition of clathrin by pitstop 2 activates the spindle assembly checkpoint and induces cell death in dividing HeLa cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Low VHL mRNA expression is associated with more aggressive tumor features of papillary thyroid carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

APC, signal transduction and genetic instability in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

KIF17 stabilizes microtubules and contributes to epithelial morphogenesis by acting at MT plus ends with EB1 and APC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

The prognostic value and therapeutic target role of stathmin-1 in urinary bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Overexpression of stathmin 1 confers an independent prognostic indicator in nasopharyngeal carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

FOXM1 mediates resistance to docetaxel in gastric cancer via up-regulating Stathmin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Proteomic identification of molecular targets of gambogic acid: role of stathmin in hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Stathmin, a new target of PRL-3 identified by proteomic methods, plays a key role in progression and metastasis of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

The APC gene in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

VHL, the story of a tumour suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Cancer cells acquire mitotic drug resistance properties through beta I-tubulin mutations and alterations in the expression of beta-tubulin isotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Human mutations that confer paclitaxel resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

No significant role for beta tubulin mutations and mismatch repair defects in ovarian cancer resistance to paclitaxel/cisplatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Mutational analysis of the class I beta-tubulin gene in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Mutation of the class I beta-tubulin gene does not predict response to paclitaxel for breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Increased α-tubulin1b expression indicates poor prognosis and resistance to chemotherapy in hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Mathematical prognostic biomarker models for treatment response and survival in epithelial ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

The roles of cys124 and ser239 in the functional properties of human betaIII tubulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

The beta isotypes of tubulin in neuronal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Phosphorylation of beta III-tubulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Different effects of vinblastine on the polymerization of isotypically purified tubulins from bovine brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Common and distinct tubulin binding sites for microtubule-associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Mutation of Ser172 in yeast β tubulin induces defects in microtubule dynamics and cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Microtubule regulation in mitosis: tubulin phosphorylation by the cyclin-dependent kinase Cdk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Expression of class III beta-tubulin reduces microtubule assembly and confers resistance to paclitaxel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Microtubule dynamics in vitro are regulated by the tubulin isotype composition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

βIII-tubulin: a novel mediator of chemoresistance and metastases in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Reactive oxygen species in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Exploring the Origin of Differential Binding Affinities of Human Tubulin Isotypes αβII, αβIII and αβIV for DAMA-Colchicine Using Homology Modelling, Molecular Docking and Molecular Dynamics Simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Microtubule-associated parameters as predictive markers of docetaxel activity in advanced breast cancer patients: results of a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Altered expression of M beta 2, the class II beta-tubulin isotype, in a murine J774.2 cell line with a high level of taxol resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Preferential binding of E7010 to murine beta 3-tubulin and decreased beta 3-tubulin in E7010-resistant cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Mechanisms of Taxol resistance related to microtubules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Markedly decreased binding of vincristine to tubulin in vinca alkaloid-resistant Chinese hamster cells is associated with selective overexpression of alpha and beta tubulin isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Increased levels of tyrosinated alpha-, beta(III)-, and beta(IV)-tubulin isotypes in paclitaxel-resistant MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Antisense oligonucleotides to class III beta-tubulin sensitize drug-resistant cells to Taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Altered beta-tubulin isotype expression in paclitaxel-resistant human prostate carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Modulation of endogenous beta-tubulin isotype expression as a result of human beta(III)cDNA transfection into prostate carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Overexpression of class III beta-tubulin predicts good response to taxane-based chemotherapy in ovarian clear cell adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Mitosis. Microtubule detyrosination guides chromosomes during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Overexpression, purification, and functional analysis of recombinant human tubulin dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

One-step purification of assembly-competent tubulin from diverse eukaryotic sources

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Correlation between protein and mRNA abundance in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Direct Analysis of Tubulin Expression in Cancer Cell Lines by Electrospray Ionization Mass Spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Intrinsically disordered tubulin tails: complex tuners of microtubule functions?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

The tubulin code: molecular components, readout mechanisms, and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Release of tyrosine from tyrosinated tubulin. Some common factors that affect this process and the assembly of tubulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Incorporation of l-Tyrosine, l-Phenylalanine and l-3,4-Dihydroxyphenylalanine as Single Units into Rat Brain Tubulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Tubulinyl-tyrosine carboxypeptidase from chicken brain: properties and partial purification

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

The distribution of tyrosyltubulin ligase in brain and other tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Characterization of the tubulin-tyrosine ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

An enzyme tyrosylating α-tubulin and its role in microtubule assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Purification of brain tubulin-tyrosine ligase by biochemical and immunological methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Motor-dependent microtubule disassembly driven by tubulin tyrosination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Regulation of microtubule motors by tubulin isotypes and post-translational modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Posttranslational modifications of alpha-tubulin: acetylated and detyrosinated forms in axons of rat cerebellum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Low expression of human tubulin tyrosine ligase and suppressed tubulin tyrosination/detyrosination cycle are associated with impaired neuronal differentiation in neuroblastomas with poor prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Expression of class III {beta}-tubulin is predictive of patient outcome in patients with non-small cell lung cancer receiving vinorelbine-based chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Differential binding regulation of microtubule-associated proteins MAP1A, MAP1B, and MAP2 by tubulin polyglutamylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Tubulin polyglutamylation is essential for airway ciliary function through the regulation of beating asymmetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Tubulin polyglutamylase enzymes are members of the TTL domain protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

The zebrafish fleer gene encodes an essential regulator of cilia tubulin polyglutamylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Tubulin tyrosine ligase like 12 links to prostate cancer through tubulin posttranslational modification and chromosome ploidy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Tubulin tyrosine ligase like 12, a TTLL family member with SET- and TTL-like domains and roles in histone and tubulin modifications and mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Association of estramustine resistance in human prostatic carcinoma cells with modified patterns of tubulin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Hyperglutamylation of tubulin can either stabilize or destabilize microtubules in the same cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Effects of tubulin acetylation and tubulin acetyltransferase binding on microtubule structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Microtubule acetylation promotes kinesin-1 binding and transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Tubulin acetylation favors Hsp90 recruitment to microtubules and stimulates the signaling function of the Hsp90 clients Akt/PKB and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

HDAC6 expression is correlated with better survival in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

α-Tubulin acetylation elevated in metastatic and basal-like breast cancer cells promotes microtentacle formation, adhesion, and invasive migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

Centromere and kinetochore gene misexpression predicts cancer patient survival and response to radiotherapy and chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-57127-0_5

10.1007/978-3-319-57127-0_5

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28600784%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference