Mad2 overexpression promotes aneuploidy and tumorigenesis in mice (Q24684680)

4

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Rocio Sotillo

object named as

Rocío Sotillo

1

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Eva Hernando

object named as

Eva Hernando

2

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author name string

Elena Díaz-Rodríguez

3

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Carlos Cordón-Cardo

5

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Scott W Lowe

6

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Robert Benezra

High-resolution genomic profiles of human lung cancer

7

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language of work or name

English

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publication date

January 2007

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published in

Cancer Cell

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volume

11

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page(s)

9-23

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issue

1

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cites work

1 reference

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Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint

7 April 2017

1 reference

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Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.

7 April 2017

1 reference

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Identification of a MAD2-binding protein, CMT2, and its role in mitosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

The role of chromosomal instability in tumor initiation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity

7 April 2017

1 reference

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Gene expression profiling predicts clinical outcome of breast cancer

7 April 2017

1 reference

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Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

7 April 2017

1 reference

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APC-dependent proteolysis of the mitotic cyclin Clb2 is essential for mitotic exit

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast

7 April 2017

1 reference

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CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

ONCOMINE: a cancer microarray database and integrated data-mining platform

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Isolation and characterization of a pituitary tumor-transforming gene (PTTG)

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

On the road to cancer: aneuploidy and the mitotic checkpoint

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Diversity of gene expression in adenocarcinoma of the lung

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Oncogene addiction: sometimes a temporary slavery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Cellular dynamics visualized in live cells in vitro and in vivo by differential dual-color nuclear-cytoplasmic fluorescent-protein expression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

The optimal rate of chromosome loss for the inactivation of tumor suppressor genes in cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

The spindle checkpoint, aneuploidy, and cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Mad2 and p53 expression profiles in colorectal cancer and its clinical significance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Mad2 phosphorylation regulates its association with Mad1 and the APC/C.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Dissecting p53 tumor suppressor functions in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Gene expression patterns in human liver cancers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Mitotic checkpoints: from yeast to cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Expression and mutational analyses of the human MAD2L1 gene in breast cancer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Cell biology: nondisjunction, aneuploidy and tetraploidy.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

BUBR1 deficiency results in abnormal megakaryopoiesis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Significance of MAD2 expression to mitotic checkpoint control in ovarian cancer cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Dual inhibition of sister chromatid separation at metaphase.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Mitotic checkpoint protein hsMAD2 as a marker predicting liver metastasis of human gastric cancers.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Correlation of defective mitotic checkpoint with aberrantly reduced expression of MAD2 protein in nasopharyngeal carcinoma cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Genetic analysis of chemoresistance in primary murine lymphomas.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850996

Application of tissue microarray technology to the study of non-Hodgkin's and Hodgkin's lymphoma

28 November 2018

1 reference

12 December 2020

APC/C-Cdc20-mediated degradation of cyclin B participates in CSF arrest in unfertilized Xenopus eggs

1 reference

12 December 2020

Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency

1 reference

12 December 2020

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1 reference

12 December 2020

Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen

1 reference

12 December 2020

The NoCut pathway links completion of cytokinesis to spindle midzone function to prevent chromosome breakage.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.10.019

7 January 2021

Activation of the anaphase-promoting complex and degradation of cyclin B is not required for progression from Meiosis I to II in Xenopus oocytes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.10.019

7 January 2021

Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.10.019

7 January 2021

Cell biology: Nondisjunction, aneuploidy and tetraploidy (Reply)

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.10.019

7 January 2021

A mutation in separase causes genome instability and increased susceptibility to epithelial cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.10.019

7 January 2021

10.1016/J.CCR.2006.10.019

Identifiers

DOI

1 reference

100925

100925

1 reference

1 reference

1 reference