Exogenous enzymes upgrade transgenesis and genetic engineering of farm animals (Q38337835)

2 September 2017

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title

Exogenous enzymes upgrade transgenesis and genetic engineering of farm animals (English)

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2 September 2017

Wilfried A Kues

10

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author name string

Pablo Bosch

1

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2 September 2017

Diego O Forcato

2

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2 September 2017

Fabrisio E Alustiza

3

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2 September 2017

Ana P Alessio

4

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2 September 2017

Alejandro E Fili

5

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2 September 2017

María F Olmos Nicotra

6

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2 September 2017

Ana C Liaudat

7

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2 September 2017

Nancy Rodríguez

8

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2 September 2017

Thirumala R Talluri

9

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2 September 2017

1 February 2015

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Cellular and Molecular Life Sciences

2 September 2017

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2 September 2017

72

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2 September 2017

10

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2 September 2017

1907-1929

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https://scigraph.springernature.com/pub.10.1007/s00018-015-1842-1

2 September 2017

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Genome engineering with targetable nucleases

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21 January 2018

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21 January 2018

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Induction of CAD gene amplification by restriction endonucleases in V79,B7 Chinese hamster cells.

21 January 2018

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Analysis of restriction enzyme-induced chromosomal aberrations by fluorescence in situ hybridization

21 January 2018

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Chromosomal aberrations and mortality of x-irradiated mammalian cells: emphasis on repair

21 January 2018

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The restriction endonuclease Alu I induces chromosomal aberrations and mutations in the hypoxanthine phosphoribosyltransferase locus, but not in the Na+/K+ ATPase locus in V79 hamster cells.

21 January 2018

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Induction of mutations at the thymidine kinase locus in CHO cells by restriction endonucleases

21 January 2018

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Homing endonucleases: DNA scissors on a mission

21 January 2018

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An intron-encoded protein is active in a gene conversion process that spreads an intron into a mitochondrial gene

21 January 2018

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Highly efficient transgenesis in Xenopus tropicalis using I-SceI meganuclease

21 January 2018

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I-SceI meganuclease mediates highly efficient transgenesis in fish.

21 January 2018

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Simple gene transfer technique based on I-SceI meganuclease and cytoplasmic injection in IVF bovine embryos.

21 January 2018

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The meganuclease I-SceI containing nuclear localization signal (NLS-I-SceI) efficiently mediated mammalian germline transgenesis via embryo cytoplasmic microinjection

21 January 2018

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Uptake of heterologous genome by mammalian spermatozoa and its transfer to ova through fertilization

21 January 2018

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Sperm cells as vectors for introducing foreign DNA into eggs: genetic transformation of mice

21 January 2018

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Sperm/DNA interaction: DNA binding proteins in sperm cell of silkworm Bombyx mori

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Mammalian transgenesis by intracytoplasmic sperm injection.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Characterization of the ICSI-mediated gene transfer method in the production of transgenic pigs

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

A unique method to produce transgenic embryos in ovine, porcine, feline, bovine and equine species.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

High rates of bovine blastocyst development after ICSI-mediated gene transfer assisted by chemical activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Foreign DNA transmission by ICSI: injection of spermatozoa bound with exogenous DNA results in embryonic GFP expression and live rhesus monkey births.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Novel method of gene transfer in birds: intracytoplasmic sperm injection for green fluorescent protein expression in quail blastoderms.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Epigenetic silencing and tissue independent expression of a novel tetracycline inducible system in double-transgenic pigs.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Recombinase-mediated mouse transgenesis by intracytoplasmic sperm injection

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Tn5 transposase-mediated mouse transgenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Increased efficiency of transgenic livestock production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

The effect of coating single- and double-stranded DNA with the recombinase A protein of Escherichia coli on transgene integration in mice.

21 January 2018

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Use of intracytoplasmic sperm injection (ICSI) to generate transgenic animals

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Germline transgenic pigs by Sleeping Beauty transposition in porcine zygotes and targeted integration in the pig genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Germline transgenesis in pigs by cytoplasmic microinjection of Sleeping Beauty transposons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Tol2: a versatile gene transfer vector in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Transposon-mediated BAC transgenesis in zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Engineering embryonic stem cells with recombinase systems

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Cas9 as a versatile tool for engineering biology

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

The origin and behavior of mutable loci in maize

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Transposable elements and their identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Initial sequencing and analysis of the human genome

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

DNA transposons: nature and applications in genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Biology of mammalian L1 retrotransposons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Resident aliens: the Tc1/mariner superfamily of transposable elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Transposon-mediated genome manipulation in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

The mechanism of transposition of Tc3 in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Technology transfer from worms and flies to vertebrates: transposition-based genome manipulations and their future perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Characterization of Sleeping Beauty transposition and its application to genetic screening in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Harnessing a high cargo-capacity transposon for genetic applications in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Transposon mediated BAC transgenesis via pronuclear injection of mouse zygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Molecular mechanisms of gene silencing mediated by DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Conditional transgenic technologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Transgene-free production of pluripotent stem cells using piggyBac transposons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

piggyBac transposase tools for genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Generation of trangenic Xenopus laevis using the Sleeping Beauty transposon system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Transgenesis in Xenopus using the Sleeping Beauty transposon system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Transposon-tagged mutagenesis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Enzymatic engineering of the porcine genome with transposons and recombinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Hyperactive transposase mutants of the Sleeping Beauty transposon

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Mutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: critical residues for DNA binding and hyperactivity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Gene transfer into genomes of human cells by the sleeping beauty transposon system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Genetic transformation of mouse embryos by microinjection of purified DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Production of transgenic rabbits, sheep and pigs by microinjection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Cytoplasmic injection of circular plasmids allows targeted expression in mammalian embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Transgenic zebrafish using transposable elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Hyperactive self-inactivating piggyBac for transposase-enhanced pronuclear microinjection transgenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Generation of transgenic pigs by cytoplasmic injection of piggyBac transposase-based pmGENIE-3 plasmids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Pig transgenesis by Sleeping Beauty DNA transposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Viable offspring derived from fetal and adult mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Sheep cloned by nuclear transfer from a cultured cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Pig transgenesis by piggyBac transposition in combination with somatic cell nuclear transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

PiggyBac transposon-mediated gene transfer in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Sleeping beauty transposase has an affinity for heterochromatin conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

High-resolution genome-wide mapping of transposon integration in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Communication between segments of DNA during site-specific recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Site-specific recombinases: changing partners and doing the twist

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Genomic targeting with a positive-selection lox integration vector allows highly reproducible gene expression in mammalian cells

21 January 2018

1 reference

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Recombinase-mediated gene activation and site-specific integration in mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Gene silencing as a threat to the success of gene therapy

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Mechanisms of site-specific recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Catalysis by site-specific recombinases

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Recombinase technology: applications and possibilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

The integrase family of recombinase: organization and function of the active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Talking about a Revolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Recombinase-mediated cassette exchange (RMCE) — A rapidly-expanding toolbox for targeted genomic modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Recombinase-mediated cassette exchange (RMCE): traditional concepts and current challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Targeted integration of DNA using mutant lox sites in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

DNA recognition by the FLP recombinase of the yeast 2 mu plasmid. A mutational analysis of the FLP binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Genomic targeting with an MBP-Cre fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Genomic targeting with purified Cre recombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Microinjection of cre recombinase RNA induces site-specific recombination of a transgene in mouse oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

An "in-out" strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements: analysis of the beta-globin locus control region

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Inactivation of the human beta-globin gene by targeted insertion into the beta-globin locus control region

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Know your neighbors: three phenotypes in null mutants of the myogenic bHLH gene MRF4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Long-range disruption of gene expression by a selectable marker cassette

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Calf removal improves conception rates to the Ovsynch and CO-Synch protocols

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Site-directed point mutations in embryonic stem cells: a gene-targeting tag-and-exchange strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Double replacement: strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by homologous recombination in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Site-specific modification of the bovine genome using Cre recombinase-mediated gene targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Establishment of a rapid and scalable gene expression system in livestock by site-specific integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Removal of selectable marker gene from fibroblast cells in transgenic cloned cattle by transient expression of Cre recombinase and subsequent effects on recloned embryo development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Excision of selectable genes from transgenic goat cells by a protein transducible TAT-Cre recombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Targeting frequency for deletion vectors in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Chromosome engineering in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Inducible gene targeting in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Cre recombinase: The universal reagent for genome tailoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Dual fluorescent reporter pig for Cre recombination: transgene placement at the ROSA26 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

A phage integrase directs efficient site-specific integration in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Site-specific recombination by phiC31 integrase and other large serine recombinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Efficient reversal of phiC31 integrase recombination in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Construction of transformed, cultured silkworm cells and transgenic silkworm using the site-specific integrase system from phage φC31.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Transgenic Xenopus laevis embryos can be generated using phiC31 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Screening of potential pseudo att sites of Streptomyces phage ΦC31 integrase in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Identification of pseudo attP sites for phage phiC31 integrase in bovine genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

ΦC31 integrase mediates efficient site-specific integration in sheep fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

PhiC31 integrase induces efficient site-specific recombination in the Capra hircus genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Pseudo attP sites in favor of transgene integration and expression in cultured porcine cells identified by Streptomyces phage phiC31 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Mutational derivatives of PhiC31 integrase with increased efficiency and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Directed evolution of a recombinase for improved genomic integration at a native human sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Accuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Phage R4 integrase mediates site-specific integration in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Phage TP901-1 site-specific integrase functions in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

A diversity of serine phage integrases mediate site-specific recombination in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Phage Bxb1 integrase mediates highly efficient site-specific recombination in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Efficient TALEN-mediated gene knockout in livestock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Targeting DNA double-strand breaks with TAL effector nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Genome Engineering With Zinc-Finger Nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Targeting DNA With Fingers and TALENs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Recent advances in targeted genome engineering in mammalian systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Targeted disruption of the alpha1,3-galactosyltransferase gene in cloned pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Production of gene-targeted sheep by nuclear transfer from cultured somatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Functional disruption of the prion protein gene in cloned goats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Production of Prnp-/- goats by gene targeting in adult fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Production of myostatin-targeted goat by nuclear transfer from cultured adult somatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Gene targeting in human somatic cells. Complete inactivation of an interferon-inducible gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Developmental and epigenetic anomalies in cloned cattle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Double-strand breaks at the target locus stimulate gene targeting in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Genetic engineering of human pluripotent cells using TALE nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Site-specific integration and tailoring of cassette design for sustainable gene transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Gene targeting with zinc finger nucleases to produce cloned eGFP knockout pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Highly efficient modification of beta-lactoglobulin (BLG) gene via zinc-finger nucleases in cattle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

TAL effectors: customizable proteins for DNA targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

The new CRISPR-Cas system: RNA-guided genome engineering to efficiently produce any desired genetic alteration in animals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

An improved zinc-finger nuclease architecture for highly specific genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Knockout of exogenous EGFP gene in porcine somatic cells using zinc-finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Genetic modifications of pigs for medicine and agriculture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Generation of GGTA1 biallelic knockout pigs via zinc-finger nucleases and somatic cell nuclear transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Precision genome engineering with programmable DNA-nicking enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Critical parameters for genome editing using zinc finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Knockout rats generated by embryo microinjection of TALENs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Highly efficient generation of heritable zebrafish gene mutations using homo- and heterodimeric TALENs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Precision editing of large animal genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Multiplex genome engineering using CRISPR/Cas systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Efficient genome editing in zebrafish using a CRISPR-Cas system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Generation of multi-gene knockout rabbits using the Cas9/gRNA system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Creating class I MHC-null pigs using guide RNA and the Cas9 endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

FOXL2 is a female sex-determining gene in the goat

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Efficient gene knockout in goats using CRISPR/Cas9 system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

One-step generation of knockout pigs by zygote injection of CRISPR/Cas system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Generation of eGFP and Cre knockin rats by CRISPR/Cas9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

DNA targeting specificity of RNA-guided Cas9 nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

CRISPR-Cas immunity and mobile DNA: a new superfamily of DNA transposons encoding a Cas1 endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Casposons: a new superfamily of self-synthesizing DNA transposons at the origin of prokaryotic CRISPR-Cas immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Development of transgenic cloned pig models of skin inflammation by DNA transposon-directed ectopic expression of human β1 and α2 integrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Efficient genetic modification and germ-line transmission of primordial germ cells using piggyBac and Tol2 transposons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

piggyBac transposition into primordial germ cells is an efficient tool for transgenesis in chickens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

A new method for producing transgenic birds via direct in vivo transfection of primordial germ cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Efficient immunoglobulin gene disruption and targeted replacement in rabbit using zinc finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Biallelic knockout of the α-1,3 galactosyltransferase gene in porcine liver-derived cells using zinc finger nucleases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Double knockout pigs deficient in N-glycolylneuraminic acid and galactose α-1,3-galactose reduce the humoral barrier to xenotransplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Generation of interleukin-2 receptor gamma gene knockout pigs from somatic cells genetically modified by zinc finger nuclease-encoding mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Highly efficient generation of GGTA1 biallelic knockout inbred mini-pigs with TALENs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

TALEN-mediated gene mutagenesis in rhesus and cynomolgus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Targeted gene knockout in chickens mediated by TALENs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

Cre-loxP-mediated gene replacement: a mouse strain producing humanized antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1842-1

hDAF expression in hearts of transgenic pigs obtained by sperm-mediated gene transfer

21 January 2018

1 reference

12 December 2020

MyoD expression marks the onset of skeletal myogenesis in Myf-5 mutant mice

1 reference

12 December 2020

Strategies for the use of site-specific recombinases in genome engineering.

1 reference

12 December 2020

Mutagenesis via insertional- or restriction enzyme-mediated-integration (REMI) as a tool to tag pathogenicity related genes in plant pathogenic fungi

1 reference

12 December 2020

Cre recombinase: the universal reagent for genome tailoring

1 reference

12 December 2020

One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system

1 reference

12 December 2020

Genomic deletions created upon LINE-1 retrotransposition

1 reference

12 December 2020

Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle

1 reference

12 December 2020

RNA-programmed genome editing in human cells

1 reference

12 December 2020

Efficient creation of an APOE knockout rabbit.

1 reference

12 December 2020

Zinc-finger nickase-mediated insertion of the lysostaphin gene into the beta-casein locus in cloned cows

1 reference

12 December 2020

Pig genomics for biomedicine

1 reference

12 December 2020

Gene integration into bovine sperm genome and its expression in transgenic offspring

1 reference

12 December 2020

On target? Tracing zinc-finger-nuclease specificity

1 reference

12 December 2020

Improved site-specific recombinase-based method to produce selectable marker- and vector-backbone-free transgenic cells.

1 reference

12 December 2020

Electroporated sperm mediation of a gene transfer system for finfish and shellfish

1 reference

12 December 2020

Site-specific cassette exchange and germline transmission with mouse ES cells expressing phiC31 integrase

1 reference

12 December 2020

Restriction enzyme-mediated integration elevates transformation frequency and enables co-transfection of Toxoplasma gondii

1 reference

12 December 2020

Exchangeable gene trap using the Cre/mutated lox system.

1 reference

12 December 2020

Genome edited sheep and cattle.

1 reference

12 December 2020

Escherichia coli XerC recombinase is required for chromosomal segregation at cell division.

1 reference

12 December 2020

Improving livestock for agriculture - technological progress from random transgenesis to precision genome editing heralds a new era.

1 reference

12 December 2020

Lentiviral transgenesis in livestock

1 reference

12 December 2020

Efficient production of transgenic chickens based on piggyBac.

1 reference

12 December 2020

Transposon-mediated transgenesis in rats

1 reference

12 December 2020

Production of transgenic cattle by pronuclear injection

1 reference

12 December 2020

DNA dose and sequence dependence in sperm-mediated gene transfer

1 reference

12 December 2020

Control of directionality in the site-specific recombination system of the Streptomyces phage phiC31

1 reference

12 December 2020

Sperm-mediated gene transfer into oocytes of the golden hamster: assessment of sperm function.

1 reference

12 December 2020

RAG1/2 knockout pigs with severe combined immunodeficiency

1 reference

12 December 2020

Viable rat offspring derived from oocytes intracytoplasmically injected with freeze-dried sperm heads.

1 reference

12 December 2020

Construction of transgenic swine with induced expression of Cre recombinase

1 reference

12 December 2020

Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant

1 reference

12 December 2020

Efficient generation of genetically distinct pigs in a single pregnancy using multiplexed single-guide RNA and carbohydrate selection.

1 reference

12 December 2020

Deletion of the alpha(1,3)galactosyl transferase (GGTA1) gene and the prion protein (PrP) gene in sheep

1 reference

12 December 2020

Germline acquisition of Cas9/RNA-mediated gene modifications in monkeys

1 reference

12 December 2020

Production of biallelic CMP-Neu5Ac hydroxylase knock-out pigs

1 reference

12 December 2020

Live pigs produced from genome edited zygotes

1 reference

12 December 2020

Lentiviral transgenesis

1 reference

12 December 2020

Co-injection of restriction enzyme with foreign DNA into the pronucleus for elevating production efficiencies of transgenic animals

1 reference

12 December 2020

Epigenetic effects on transgene expression.

1 reference

12 December 2020

Strategies for selection marker-free swine transgenesis using the Sleeping Beauty transposon system

1 reference

12 December 2020

A profile of native integration sites used by φC31 integrase in the bovine genome

1 reference

12 December 2020

Knockout mice created by TALEN-mediated gene targeting

1 reference

12 December 2020

Conspiracy of silence among repeated transgenes.

1 reference

12 December 2020

The effectiveness of restriction endonucleases in cell killing and mutation

1 reference

12 December 2020

Generation of CRISPR/Cas9-mediated gene-targeted pigs via somatic cell nuclear transfer.

1 reference

12 December 2020

No simple solution for making transgenic mice

1 reference

12 December 2020

Single-step generation of rabbits carrying a targeted allele of the tyrosinase gene using CRISPR/Cas9.

1 reference

12 December 2020

Safe harbours for the integration of new DNA in the human genome

1 reference

12 December 2020

Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice

1 reference

12 December 2020

10.1007/S00018-015-1842-1

Identifiers

DOI

1 reference

2 September 2017

1 reference