Transposon-mediated genome manipulation in vertebrates (Q24623786)

Europe PubMed Central

title

Transposon-mediated genome manipulation in vertebrates (English)

0 references

0 references

Jef D Boeke

4

0 references

Andras Nagy

object named as

Andras Nagy

5

0 references

Zoltán Ivics

1

object named as

Zoltán Ivics

0 references

Zsuzsanna Izsvák

7

object named as

Zsuzsanna Izsvák

0 references

author name string

Meng Amy Li

2

0 references

Lajos Mátés

3

0 references

Allan Bradley

Disease-specific induced pluripotent stem cells

6

0 references

language of work or name

English

0 references

publication date

June 2009

0 references

published in

Nature Methods

0 references

volume

6

0 references

page(s)

415-22

0 references

issue

6

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

The ancient mariner sails again: transposition of the human Hsmar1 element by a reconstructed transposase and activities of the SETMAR protein on transposon ends

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Enhancer trapping in zebrafish using the Sleeping Beauty transposon

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Initial sequencing and analysis of the human genome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Lessons from hereditary colorectal cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Cancer predisposition caused by elevated mitotic recombination in Bloom mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: a mechanism for non-LTR retrotransposition

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

A DNA transposon-based approach to validate oncogenic mutations in the mouse

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

High-resolution genome-wide mapping of transposon integration in mammals

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Regulated transposition of a fish transposon in the mouse germ line

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

A transposon-based genetic screen in mice identifies genes altered in colorectal cancer

7 April 2017

1 reference

https://api.crossref.org/works/10.1038/NMETH.1332

Transposition of a reconstructed Harbinger element in human cells and functional homology with two transposon-derived cellular genes

22 April 2017

1 reference

https://api.crossref.org/works/10.1038/NMETH.1332

Effective targeted gene 'knockdown' in zebrafish

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Reverse Transcriptase Encoded by a Human Transposable Element

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

7 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Conditional activation of a single-copy L1 transgene in mice by Cre.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Chromosomal transposition of PiggyBac in mouse embryonic stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Progress and prospects in rat genetics: a community view.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Transposon-mediated mutagenesis in somatic cells: identification of transposon-genomic DNA junctions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Transposons for cancer gene discovery: Sleeping Beauty and beyond

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Technology transfer from worms and flies to vertebrates: transposition-based genome manipulations and their future perspectives

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

A recessive genetic screen for host factors required for retroviral infection in a library of insertionally mutated Blm-deficient embryonic stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Stable integration and conditional expression of electroporated transgenes in chicken embryos

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

PiggyBac transposon-mediated gene transfer in human cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Active retrotransposition by a synthetic L1 element in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Harnessing a high cargo-capacity transposon for genetic applications in vertebrates

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Functional dissection of the Tol2 transposable element identified the minimal cis-sequence and a highly repetitive sequence in the subterminal region essential for transposition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Sleeping beauty transposon-based phenotypic analysis of mice: lack of Arpc3 results in defective trophoblast outgrowth

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Sleeping beauty: a novel cancer gene discovery tool

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

RNA as a source of transposase for Sleeping Beauty-mediated gene insertion and expression in somatic cells and tissues

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

A transposon-mediated gene trap approach identifies developmentally regulated genes in zebrafish

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Genome-wide phenotype analysis in ES cells by regulated disruption of Bloom's syndrome gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

A public gene trap resource for mouse functional genomics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Transposition of the Tol2 element, an Ac-like element from the Japanese medaka fish Oryzias latipes, in mouse embryonic stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Development of hyperactive sleeping beauty transposon vectors by mutational analysis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Characterization of Sleeping Beauty transposition and its application to genetic screening in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

The Frog Prince: a reconstructed transposon from Rana pipiens with high transpositional activity in vertebrate cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Transposon Mutagenesis of the Mouse Germline

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Human L1 element target-primed reverse transcription in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Mammalian germ-line transgenesis by transposition.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Twin priming: a proposed mechanism for the creation of inversions in L1 retrotransposition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

In vivo transposition of Minos, a Drosophila mobile element, in mammalian tissues

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Efficient chromosomal transposition of a Tc1/mariner- like transposon Sleeping Beauty in mice.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Transposition and gene disruption in the male germline of the mouse

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Dual-tagging gene trap of novel genes in Drosophila melanogaster

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Identification of a functional transposase of the Tol2 element, an Ac-like element from the Japanese medaka fish, and its transposition in the zebrafish germ lineage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Sleeping Beauty, a wide host-range transposon vector for genetic transformation in vertebrates

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Target-selected gene inactivation in Caenorhabditis elegans by using a frozen transposon insertion mutant bank

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Site-selected insertion of the transposon Tc1 into a Caenorhabditis elegans myosin light chain gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Insertional mutagenesis of the Drosophila genome with single P elements

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Tol2 transposon-mediated enhancer trap to identify developmentally regulated zebrafish genes in vivo.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

The Tol1 element of medaka fish is transposed with only terminal regions and can deliver large DNA fragments into the chromosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Transposons for gene therapy!

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Generation of an inducible and optimized piggyBac transposon system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Germ-line transgenesis of the Tc1/mariner superfamily transposon Minos in Ciona intestinalis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Germline transgenesis of zebrafish using the medaka Tol1 transposon system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Tol2 transposon-mediated transgenesis in Xenopus tropicalis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Efficient gene delivery and gene expression in zebrafish using the Sleeping Beauty transposon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Generation of trangenic Xenopus laevis using the Sleeping Beauty transposon system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Transposon-mediated enhancer trapping in medaka.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Insertional mutagenesis of the mouse germline with Sleeping Beauty transposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Transposon-tagged mutagenesis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Transposition of the Drosophila hydei Minos transposon in the mouse germ line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Toward simpler and faster genome-wide mutagenesis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Passport, a native Tc1 transposon from flatfish, is functionally active in vertebrate cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Trans-kingdom transposition of the maize dissociation element

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

A highly active synthetic mammalian retrotransposon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Targeting of human retrotransposon integration is directed by the specificity of the L1 endonuclease for regions of unusual DNA structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

Target-site preferences of Sleeping Beauty transposons.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Common physical properties of DNA affecting target site selection of sleeping beauty and other Tc1/mariner transposable elements.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Mechanisms of tolerance to DNA damaging therapeutic drugs

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Mobilization of a Drosophila transposon in the Caenorhabditis elegans germ line.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Selection for transgene homozygosity in embryonic stem cells results in extensive loss of heterozygosity

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867038

Genotype-based screen for ENU-induced mutations in mouse embryonic stem cells

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19478801

12 December 2020

inferred from PubMed ID database lookup

Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon system

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19478801

12 December 2020

inferred from PubMed ID database lookup

Gene-breaking transposon mutagenesis reveals an essential role for histone H2afza in zebrafish larval development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19478801

12 December 2020

inferred from PubMed ID database lookup

Sleeping Beauty transposon for efficient gene delivery.

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

7 January 2021

inferred from DOI database lookup

A piggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

7 January 2021

inferred from DOI database lookup

Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1332

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NMETH.1332

1 reference

Dimensions Publication ID

829679

1046510479

0 references

829679

1 reference

1 reference

1 reference