Talking about a Revolution (Q30050478)

https://doi.org/10.1016%2FS1534-5807%2803%2900399-X

25 May 2017

author name string

Catherine S. Branda

series ordinal

1

1 reference

https://doi.org/10.1016%2FS1534-5807%2803%2900399-X

25 May 2017

Susan M. Dymecki

series ordinal

2

1 reference

https://doi.org/10.1016%2FS1534-5807%2803%2900399-X

25 May 2017

publication date

January 2004

1 reference

https://doi.org/10.1016%2FS1534-5807%2803%2900399-X

25 May 2017

language of work or name

English

0 references

number of pages

22

1 reference

inferred from page(s)

published in

Developmental Cell

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https://doi.org/10.1016%2FS1534-5807%2803%2900399-X

25 May 2017

volume

6

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https://doi.org/10.1016%2FS1534-5807%2803%2900399-X

25 May 2017

issue

1

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https://doi.org/10.1016%2FS1534-5807%2803%2900399-X

25 May 2017

page(s)

7-28

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https://doi.org/10.1016%2FS1534-5807%2803%2900399-X

Cre-mediated somatic site-specific recombination in mice

25 May 2017

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Simplified generation of targeting constructs using ET recombination

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Targeted integration of DNA using mutant lox sites in embryonic stem cells

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7 January 2021

Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders

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Site-directed point mutations in embryonic stem cells: a gene-targeting tag-and-exchange strategy

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7 January 2021

An Flp indicator mouse expressing alkaline phosphatase from the ROSA26 locus.

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7 January 2021

Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation

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Coping with kinetic and thermodynamic barriers: RMCE, an efficient strategy for the targeted integration of transgenes

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Site-specific cassette exchange and germline transmission with mouse ES cells expressing phiC31 integrase

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7 January 2021

Segmental genomic replacement by Cre-mediated recombination: genotoxic stress activation of the p53 promoter in single-copy transformants

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7 January 2021

Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines

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7 January 2021

Spatio-temporally controlled site-specific somatic mutagenesis in the mouse.

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7 January 2021

Alteration of Cre recombinase site specificity by substrate-linked protein evolution.

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7 January 2021

Different thermostabilities of FLP and Cre recombinases: implications for applied site-specific recombination

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7 January 2021

Improved properties of FLP recombinase evolved by cycling mutagenesis

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7 January 2021

Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP-mediated recombination in the mouse.

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7 January 2021

An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy

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7 January 2021

Lineage analysis using retrovirus vectors

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7 January 2021

Recombination deficient mutants of E. coli and other bacteria

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7 January 2021

A gene-driven approach to the identification of ENU mutants in the mouse

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7 January 2021

Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development.

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7 January 2021

Use of a yeast site-specific recombinase to generate embryonic mosaics in Drosophila

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7 January 2021

Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase

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7 January 2021

Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice

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7 January 2021

Using Flp-Recombinase to Characterize Expansion ofWnt1-Expressing Neural Progenitors in the Mouse

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7 January 2021

Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation

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7 January 2021

Establishment in culture of pluripotential cells from mouse embryos

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7 January 2021

Widespread recombinase expression using FLPeR (flipper) mice

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7 January 2021

Ligand-activated site-specific recombination in mice

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7 January 2021

Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains

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7 January 2021

Site-specific chromosomal integration in mammalian cells: highly efficient CRE recombinase-mediated cassette exchange

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7 January 2021

A recombinant retrovirus encoding alkaline phosphatase confirms clonal boundary assignment in lineage analysis of murine retina

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7 January 2021

Neurons and glia arise from a common progenitor in chicken optic tectum: demonstration with two retroviruses and cell type-specific antibodies

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7 January 2021

The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome

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7 January 2021

Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication

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7 January 2021

A gene expression atlas of the central nervous system based on bacterial artificial chromosomes

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7 January 2021

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

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7 January 2021

Transgenesis by means of blastocyst-derived embryonic stem cell lines

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7 January 2021

Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes

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7 January 2021

A phage integrase directs efficient site-specific integration in human cells

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7 January 2021

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

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7 January 2021

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

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7 January 2021

A Cre recombinase transgene with mosaic, widespread tamoxifen-inducible action

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7 January 2021

A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome

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7 January 2021

Gene-trap-based target site for cre-mediated transgenic insertion

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7 January 2021

Long-term, noninvasive imaging of regulated gene expression in living mice

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7 January 2021

Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse

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7 January 2021

Bac to the future: The use of bac transgenic mice for neuroscience research

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7 January 2021

Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis

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7 January 2021

P1 site-specific recombination: nucleotide sequence of the recombining sites

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7 January 2021

Formation of small circular DNA molecules via an in vitro site-specific recombination system

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7 January 2021

The role of the loxP spacer region in P1 site-specific recombination

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7 January 2021

Genome-wide, large-scale production of mutant mice by ENU mutagenesis.

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7 January 2021

Cre/loxP recombination-activated neuronal markers in mouse neocortex and hippocampus

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7 January 2021

Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases

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7 January 2021

Normal fate and altered function of the cardiac neural crest cell lineage in retinoic acid receptor mutant embryos

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7 January 2021

Mouse ENU mutagenesis

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7 January 2021

Removal of the floxed neo gene from a conditional knockout allele by the adenoviral Cre recombinase in vivo

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7 January 2021

A novel reporter mouse strain that expresses enhanced green fluorescent protein upon Cre-mediated recombination

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7 January 2021

Regulation of Cre recombinase activity by the synthetic steroid RU 486.

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7 January 2021

Vital dye mapping of the gastrula and neurula of Xenopus laevis. I. Prospective areas and morphogenetic movements of the superficial layer

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7 January 2021

Vital dye mapping of the gastrula and neurula of Xenopus laevis. II. Prospective areas and morphogenetic movements of the deep layer

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7 January 2021

Functional genetic analysis of mouse chromosome 11

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7 January 2021

Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice

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7 January 2021

Selection-marker-free modification of the murine beta-casein gene using a lox2272 [correction of lox2722] site

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7 January 2021

Inactivating the beta 2-microglobulin locus in mouse embryonic stem cells by homologous recombination

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7 January 2021

A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice

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7 January 2021

Inducible gene targeting in mice

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7 January 2021

Targeted oncogene activation by site-specific recombination in transgenic mice

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7 January 2021

Initial sequencing and analysis of the human genome

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A genetic screen identifies novel non-compatible loxP sites.

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7 January 2021

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7 January 2021

Role of nucleotide sequences of loxP spacer region in Cre-mediated recombination

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7 January 2021

Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles

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Zp3-cre, a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ line

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7 January 2021

Fgf8 signalling from the AER is essential for normal limb development.

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7 January 2021

Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis

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7 January 2021

Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells

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7 January 2021

Progress in sequencing the mouse genome

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7 January 2021

Efficient Cre-loxP–induced mitotic recombination in mouse embryonic stem cells

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7 January 2021

A highly efficient recombineering-based method for generating conditional knockout mutations

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7 January 2021

The segregation of the SbcA and Rac phenotypes in an Escherichia coli recB − mutant

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7 January 2021

Z/AP, a double reporter for cre-mediated recombination

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7 January 2021

Ligand-regulated site-specific recombination

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7 January 2021

Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells

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7 January 2021

Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice

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7 January 2021

Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain

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7 January 2021

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

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7 January 2021

Identification of the crossover site during FLP-mediated recombination in the Saccharomyces cerevisiae plasmid 2 microns circle

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7 January 2021

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

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7 January 2021

Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase

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7 January 2021

An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

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7 January 2021

Efficient gene-specific expression of cre recombinase in the mouse embryo by targeted insertion of a novel IRES-Cre cassette into endogenous loci.

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7 January 2021

From mouse to man: generating megabase chromosome rearrangements

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7 January 2021

Functional analysis of secreted and transmembrane proteins critical to mouse development.

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7 January 2021

Use of bacteriophage lambda recombination functions to promote gene replacement in Escherichia coli

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7 January 2021

Rapid modification of bacterial artificial chromosomes by ET-recombination.

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7 January 2021

Point mutation of bacterial artificial chromosomes by ET recombination

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7 January 2021

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

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7 January 2021

Efficient selection for high-expression transfectants with a novel eukaryotic vector

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7 January 2021

Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p

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7 January 2021

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse

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7 January 2021

Recombinase-mediated gene activation and site-specific integration in mammalian cells

1 reference

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7 January 2021

Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Tissue- and site-specific DNA recombination in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes

1 reference

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7 January 2021

Flp recombinase regulated lacZ expression at the ROSA26 locus

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Mouse models of human chromosomal translocations and approaches to cancer therapy

1 reference

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7 January 2021

Chromosome engineering in mice

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Origin of the precerebellar system.

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Directed evolution of the site specificity of Cre recombinase

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Stringent doxycycline dependent control of CRE recombinase in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Temporally and spatially regulated somatic mutagenesis in mice

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Rapid generation of inducible mouse mutants

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

DNA recognition by the FLP recombinase of the yeast 2 mu plasmid. A mutational analysis of the FLP binding site

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7 January 2021

Codon-improved Cre recombinase (iCre) expression in the mouse

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

The temporal requirement for endothelin receptor-B signalling during neural crest development

1 reference

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7 January 2021

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Capturing genes encoding membrane and secreted proteins important for mouse development

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Generalized lacZ expression with the ROSA26 Cre reporter strain

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Temporal control of the Cre recombinase in transgenic mice by a tetracycline responsive promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Gene-trap mutagenesis: past, present and beyond

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Efficient control of tetracycline-responsive gene expression from an autoregulated bi-directional expression vector

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Nested chromosomal deletions induced with retroviral vectors in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Creating a transloxation. Engineering interchromosomal translocations in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Endothelium-specific replacement of the connexin43 coding region by a lacZ reporter gene

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Selective Disruption of Genes Transiently Induced in Differentiating Mouse Embryonic Stem Cells by Using Gene Trap Mutagenesis and Site-Specific Recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Mammalian genomes contain active recombinase recognition sites

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Subregion- and cell type-restricted gene knockout in mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Lineage-independent determination of cell type in the embryonic mouse retina

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Cre-mediated site-specific translocation between nonhomologous mouse chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

The Sequence of the Human Genome

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Stepwise manipulation of DNA specificity in Flp recombinase: progressively adapting Flp to individual and combinatorial mutations in its target site

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Widespread Dispersion of Neuronal Clones Across Functional Regions of the Cerebral Cortex

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: phenotypic consequences of gene dosage imbalance.

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Identification of genes differentially regulated by glucocorticoids and progestins using a Cre/loxP-mediated retroviral promoter-trapping strategy

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Initial sequencing and comparative analysis of the mouse genome

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Double replacement: strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by homologous recombination in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

New variants of inducible Cre recombinase: a novel mutant of Cre-PR fusion protein exhibits enhanced sensitivity and an expanded range of inducibility

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Homologous recombination based modification in Esherichia coli and germline transmission in transgenic mice of a bacterial artificial chromsome

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Recombineering with overlapping single-stranded DNA oligonucleotides: testing a recombination intermediate

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Engineering chromosomal rearrangements in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Towards genetic genome projects: genomic library screening and gene-targeting vector construction in a single step

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

A new logic for DNA engineering using recombination in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

DNA cloning by homologous recombination in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Engineering mouse chromosomes with Cre-loxP: range, efficiency, and somatic applications

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Introducing defined chromosomal rearrangements into the mouse genome

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

In utero activation of K5.CrePR1 induces gene deletion

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Fate mapping of the mouse midbrain–hindbrain constriction using a site-specific recombination system

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Transient expression of the bHLH factor neurogenin-2 marks a subpopulation of neural crest cells biased for a sensory but not a neuronal fate

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021

Cre-loxP-mediated gene replacement: a mouse strain producing humanized antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900399-X

7 January 2021