Do glial cells play an anti-oxidative role in Huntington's disease? (Q38222578)

31 August 2017

Do glial cells play an anti-oxidative role in Huntington's disease? (English)

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31 August 2017

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Y Gao

1

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31 August 2017

S-F Chu

2

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31 August 2017

J-P Li

3

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31 August 2017

W Zuo

4

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31 August 2017

Z-L Wen

5

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31 August 2017

W-B He

6

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31 August 2017

J-Q Yan

7

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31 August 2017

N-H Chen

8

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31 August 2017

14 August 2014

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31 August 2017

Free Radical Research

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31 August 2017

48

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31 August 2017

10

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31 August 2017

1135-1144

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Oxidative stress-mediated regulation of proteasome complexes

31 August 2017

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Ameliorative effects of Bacopa monniera on lead-induced oxidative stress in different regions of rat brain

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation.

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Mitochondria: dynamic organelles in disease, aging, and development

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Increased energy metabolism rescues glia-induced pathology in a Drosophila model of Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Protection by glia-conditioned medium in a cell model of Huntington disease

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Proteomic and oxidative stress analysis in human brain samples of Huntington disease.

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

The selective vulnerability of nerve cells in Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

3-Nitropropionic acid as a tool to study the mechanisms involved in Huntington's disease: past, present and future.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Prospects for neuroprotective therapies in prodromal Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Mitochondrial functions in astrocytes: neuroprotective implications from oxidative damage by rotenone

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Mechanisms of neurodegeneration in Huntington's disease.

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Brain protein oxidation in age-related neurodegenerative disorders that are associated with aggregated proteins

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Increased glutathione levels in cortical and striatal mitochondria of the R6/2 Huntington's disease mouse model

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease?

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Oxidative damage in Huntington's disease pathogenesis

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Animal models of Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

The Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseases

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Oxidative stress and neuronal DNA fragmentation mediate age-dependent vulnerability to the mitochondrial toxin, 3-nitropropionic acid, in the mouse striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Involvement of superoxide in excitotoxicity and DNA fragmentation in striatal vulnerability in mice after treatment with the mitochondrial toxin, 3-nitropropionic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Excitotoxicity is required for induction of oxidative stress and apoptosis in mouse striatum by the mitochondrial toxin, 3-nitropropionic acid

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

White matter damage following systemic injection of the mitochondrial inhibitor 3-nitropropionic acid in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

3-Nitropropionate, the toxic substance of Indigofera , is a suicide inactivator of succinate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Choosing an animal model for the study of Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Proteomic analysis of protein expression and oxidative modification in r6/2 transgenic mice: a model of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Cross talk between activation of microglia and astrocytes in pathological conditions in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Central neuron-glial and glial-glial interactions following axon injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Targeting reactive astrogliosis by novel biotechnological strategies.

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Astrocytes and microglia: responses to neuropathological conditions

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Astrocyte-specific overexpression of Nrf2 protects striatal neurons from mitochondrial complex II inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Cross-talk between neurons and astrocytes in response to bilirubin: early beneficial effects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Astrocytic-neuronal crosstalk: implications for neuroprotection from brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Cytochrome c oxidase isoform IV-2 is involved in 3-nitropropionic acid-induced toxicity in striatal astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Mechanisms of Disease: astrocytes in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Estrogen and the development and protection of nigrostriatal dopaminergic neurons: concerted action of a multitude of signals, protective molecules, and growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Neuroprotective agents in brain injury: a partial failure?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Antioxidant and bioenergetic coupling between neurons and astrocytes.

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Astrocyte-neuron metabolic relationships: for better and for worse

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

The Nrf2-ARE cytoprotective pathway in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Phagocytosis of microglia in the central nervous system diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

The role of microglia and macrophages in the pathophysiology of the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Microglia: Intrinsic immuneffector cell of the brain

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Microglia in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Perineuronal microglial reactivity following proximal and distal axotomy of rat rubrospinal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Microglial cells protect cerebellar granule neurons from apoptosis: evidence for reciprocal signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

The hunt for huntingtin function: interaction partners tell many different stories

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Polyglutamines stop traffic: axonal transport as a common target in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Microglia and neuroinflammation: a pathological perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Astrocyte activation and reactive gliosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Striatal infusion of glial conditioned medium diminishes huntingtin pathology in r6/1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Differential activities of the ubiquitin-proteasome system in neurons versus glia may account for the preferential accumulation of misfolded proteins in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Reactive oxygen species: stuck in the middle of neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Small molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

The Nrf2 system as a potential target for the development of indirect antioxidants.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

The Nrf2-Keap1-ARE signaling pathway: The regulation and dual function of Nrf2 in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Modulation of Nrf2/ARE pathway by food polyphenols: a nutritional neuroprotective strategy for cognitive and neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Mechanisms of Nrf2 protection in astrocytes as identified by quantitative proteomics and siRNA screening

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Role of nicotinamide quinone oxidoreductase 1 (NQO1) in protection against toxicity of electrophiles and reactive oxygen intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Identification of retinoic acid as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Nrf2 as a novel molecular target for chemoprevention

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

Nrf2, a multi-organ protector?

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2014.936432

An important role of Nrf2-ARE pathway in the cellular defense mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

New insights into antioxidant strategies against paraquat toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

The mystery and magic of glia: a perspective on their roles in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2014.936432

10.3109/10715762.2014.936432

21 January 2018

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DOI

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31 August 2017

1 reference