Alkaloids as a source of potential anticholinesterase inhibitors for the treatment of Alzheimer's disease (Q38162961)

30 August 2017

Alkaloids as a source of potential anticholinesterase inhibitors for the treatment of Alzheimer's disease (English)

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30 August 2017

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Eduardo Luis Konrath

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30 August 2017

Carolina dos Santos Passos

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2

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30 August 2017

Luiz Carlos Klein

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3

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30 August 2017

Amélia T Henriques

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4

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30 August 2017

20 June 2013

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Journal of Pharmacy and Pharmacology

30 August 2017

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30 August 2017

65

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30 August 2017

12

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30 August 2017

1701-1725

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Forecasting the global burden of Alzheimer’s disease

30 August 2017

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https://api.crossref.org/works/10.1111%2FJPHP.12090

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Global prevalence of dementia: a Delphi consensus study

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

An Alzheimer's disease-specific beta-amyloid fragment signature in cerebrospinal fluid

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Alzheimer disease: Alzheimer disease neuropathology in the oldest old.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

The significance of the cholinergic system in the brain during aging and in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

New potent acetylcholinesterase inhibitors in the tetracyclic triterpene series

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Current pharmacotherapy for Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Alzheimer's disease: clinical trials and drug development

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Perspective: in search of biomarkers.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Animal models of Alzheimer's disease and evaluation of anti-dementia drugs

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Animal models in the drug discovery pipeline for Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Pathways towards and away from Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Alzheimer's disease: a tangled issue.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Endogenous overproduction of beta-amyloid induces tau hyperphosphorylation and decreases the solubility of tau in N2a cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Emerging beta-amyloid therapies for the treatment of Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Structure and function of amyloid in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Genetics of Alzheimer disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Memory function and brain glucose metabolism

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Oxidative stress and protein aggregation during biological aging

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Anti-amyloidogenic and anti-apoptotic role of melatonin in Alzheimer disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Basal forebrain cholinergic dysfunction in Alzheimer's disease--interrelationship with beta-amyloid, inflammation and neurotrophin signaling

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Tau therapeutic strategies for the treatment of Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

The role of cholinergic agents in the management of behavioural disturbances in Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Cholinesterases: new roles in brain function and in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Interactions between the amyloid and cholinergic mechanisms in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Neurochemical basis for symptomatic treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

The prevalence of dementia is changing over time in Rochester, Minnesota

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Acetylcholinesterase inhibitors as disease-modifying therapies for Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Cholinesterases: roles in the brain during health and disease.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Natural products and their derivatives as cholinesterase inhibitors in the treatment of neurodegenerative disorders: an update

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Novel cholinesterase inhibitors as future effective drugs for the treatment of Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

An overview on natural cholinesterase inhibitors--a multi-targeted drug class--and their mass production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Tacrine in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Donepezil (Aricept) for treatment of Alzheimer's disease and other dementing conditions

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Treatment of Alzheimer's disease: current status and new perspectives.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

The pharmacology of galanthamine and its analogues

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Cholinesterase inhibitors used in the treatment of Alzheimer's disease: the relationship between pharmacological effects and clinical efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Acetylcholinesterase enzyme inhibitory effects of amaryllidaceae alkaloids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Current Treatment for Alzheimer Disease and Future Prospects

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Medicinal plants and Alzheimer's disease: from ethnobotany to phytotherapy

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Natural Product Inhibitors of Acetylcholinesterase

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Acetylcholinesterase inhibitors from plants and fungi

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Acetylcholinesterase inhibitors from plants.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Lead finding for acetyl cholinesterase inhibitors from natural origin: structure activity relationship and scope

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Pharmacological effects of Catharanthus roseus root alkaloids in acetylcholinesterase inhibition and cholinergic neurotransmission.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Screening of non-alkaloidal natural compounds as acetylcholinesterase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

A multicenter double-blind study of controlled-release physostigmine for the treatment of symptoms secondary to Alzheimer's disease. Physostigmine Study Group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Huperzine A from Huperzia species--an ethnopharmacolgical review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Neuroprotective effects of huperzine A: new therapeutic targets for neurodegenerative disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Comparative effects of huperzine A, donepezil and rivastigmine on cortical acetylcholine level and acetylcholinesterase activity in rats

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

A phase II trial of huperzine A in mild to moderate Alzheimer disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJPHP.12090

21 January 2018

The Lycopodium alkaloids

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https://api.crossref.org/works/10.1111%2FJPHP.12090

Acetylcholinesterase inhibitory activity of some Amaryllidaceae alkaloids and Narcissus extracts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Effect of isoquinoline alkaloids from two Hippeastrum species on in vitro acetylcholinesterase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Inhibitory effect of corynoline isolated from the aerial parts of Corydalis incisa on the acetylcholinesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Acetylcholinesterase inhibitors from the aerial parts of Corydalis speciosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Anticholinesterase activity in an alkaloid extract of Huperzia saururus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Investigation of the in vitro and ex vivo acetylcholinesterase and antioxidant activities of traditionally used Lycopodium species from South America on alkaloid extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Indole alkaloids from Tabernaemontana australis (Muell. Arg) Miers that inhibit acetylcholinesterase enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Diterpenoid and steroidal alkaloids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

New pregnane-type steroidal alkaloids from Sarcocca saligna and their cholinesterase inhibitory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Cholinesterase inhibiting and antiplasmodial steroidal alkaloids from Sarcococca hookeriana.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Cholinesterase inhibitory and spasmolytic potential of steroidal alkaloids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Steroidal alkaloids from the leaves of Sarcococca coriacea of Nepalese origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Presence of antispasmodic, antidiarrheal, antisecretory, calcium antagonist and acetylcholinesterase inhibitory steroidal alkaloids in Sarcococca saligna.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Molecular docking studies of natural cholinesterase-inhibiting steroidal alkaloids from Sarcococca saligna

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Structure-fragmentation relationship and rapid dereplication of Buxus steroidal alkaloids by electrospray ionization-quadrupole time-of-flight mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Acetyl and butyrylcholinesterase-inhibiting triterpenoid alkaloids from Buxus papillosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

New cholinesterase-inhibiting triterpenoid alkaloids from Buxus hyrcana.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Triterpenoidal alkaloids from Buxus hyrcana and their enzyme inhibitory, anti-fungal and anti-leishmanial activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Triterpenoidal alkaloids from Buxus natalensis and their acetylcholinesterase inhibitory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Structural basis of acetylcholinesterase inhibition by triterpenoidal alkaloids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Characterization and identification of steroidal alkaloids in Fritillaria species using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Inhibitors of acetylcholine esterase in vitro--screening of steroidal alkaloids from Fritillaria species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Acetylcholinesterase inhibitory activity of lycopodane-type alkaloids from the Icelandic Lycopodium annotinum ssp. alpestre

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Cryptadines A and B, novel C27N3-type pentacyclic alkaloids from Lycopodium cryptomerinum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Carinatumins A-C, new alkaloids from Lycopodium carinatum inhibiting acetylcholinesterase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Sieboldine A, a Novel Tetracyclic Alkaloid from Lycopodium sieboldii, Inhibiting Acetylcholinesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Acetylcholinesterase-inhibiting alkaloids from Zephyranthes concolor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Three-dimensional structure of a complex of galanthamine (Nivalin) with acetylcholinesterase from Torpedo californica: implications for the design of new anti-Alzheimer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Isolation of the acetylcholinesterase inhibitor ungeremine from Nerine bowdenii by preparative HPLC coupled on-line to a flow assay system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Choline esterase inhibitory properties of alkaloids from two Nigerian Crinum species

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Cytotoxicity and acetylcholinesterase inhibitory activity of an isolated crinine alkaloid from Boophane disticha (Amaryllidaceae).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Acetylcholinesterase inhibitors from Stephania venosa tuber.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Cholinesterase inhibitory and anti-amnesic activity of alkaloids from Corydalis turtschaninovii.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Alkaloids from roots of Stephania rotunda and their cholinesterase inhibitory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Anti-Alzheimer and antioxidant activities of Coptidis Rhizoma alkaloids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Berberine: a potential multipotent natural product to combat Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Berberine alters the processing of Alzheimer's amyloid precursor protein to decrease Abeta secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Acetylcholinesterase inhibitors from Corydalis yanhusuo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Acetylcholinesterase and butyrylcholinesterase inhibitory compounds from Corydalis cava Schweigg. & Kort

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Anti-acetylcholinesterase, anti-α-glucosidase, anti-leishmanial and anti-fungal activities of chemical constituents of Beilschmiedia species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

New cholinesterase inhibiting bisbenzylisoquinoline alkaloids from Cocculus pendulus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Acetylcholinesterase inhibitors from the toadstool Cortinarius infractus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Nostocarboline: isolation and synthesis of a new cholinesterase inhibitor from Nostoc 78-12A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Juliflorine: a potent natural peripheral anionic-site-binding inhibitor of acetylcholinesterase with calcium-channel blocking potential, a leading candidate for Alzheimer's disease therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Haloxylines A and B, antifungal and cholinesterase inhibiting piperidine alkaloids from Haloxylon salicornicum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Petrosamine, a potent anticholinesterase pyridoacridine alkaloid from a Thai marine sponge Petrosia n. sp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Alkaloids from stems of Esenbeckia leiocarpa Engl. (Rutaceae) as potential treatment for Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Benzylphenethylamine alkaloids from Hosta plantaginea with inhibitory activity against tobacco mosaic virus and acetylcholinesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

The cholinergic hypothesis of Alzheimer's disease: a review of progress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

In-vitro evaluation of the P-glycoprotein interactions of a series of potentially CNS-active Amaryllidaceae alkaloids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Selective cytochrome P450 3A4 inhibitory activity of Amaryllidaceae alkaloids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Molecular basis of inhibitory activities of berberine against pathogenic enzymes in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12090

Pregnane-Type Steroidal Alkaloids ofSarcococca saligna: a New Class of Cholinesterase Inhibitors

21 January 2018

0 references

Cholinesterase-Inhibiting New Steroidal Alkaloids fromSarcococca hookeriana of Nepalese Origin

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/HLCA.200490100

New Cholinesterase-Inhibiting Steroidal Alkaloids fromSarcococca saligna

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/HLCA.200490042

Current Concepts on Selected Plant Secondary Metabolites With Promising Inhibitory Effects Against Enzymes Linked to Alzheimer's Disease

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.2174/092986712800229032

New cholinesterase inhibiting steroidal alkaloids from the leaves of Sarcococca coriacea of Nepalese origin

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1248/CPB.50.1423

New steroidal alkaloids from Fritillaria imperialis and their cholinesterase inhibiting activities

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1248/CPB.50.1013

Identifiers

DOI

10.1111/JPHP.12090

1 reference

30 August 2017

1 reference