Endogenous overproduction of beta-amyloid induces tau hyperphosphorylation and decreases the solubility of tau in N2a cells (Q40271638)

19 September 2017

Endogenous overproduction of beta-amyloid induces tau hyperphosphorylation and decreases the solubility of tau in N2a cells (English)

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19 September 2017

Y-P Wang

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19 September 2017

X-C Wang

2

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19 September 2017

Q Tian

3

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19 September 2017

Y Yang

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19 September 2017

Q Zhang

5

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19 September 2017

J-Y Zhang

6

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19 September 2017

Y-C Zhang

7

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19 September 2017

Z-F Wang

8

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19 September 2017

Q Wang

9

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19 September 2017

H Li

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19 September 2017

J-Z Wang

11

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19 September 2017

6 June 2006

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Journal of Neural Transmission

19 September 2017

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19 September 2017

113

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19 September 2017

11

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19 September 2017

1723-1732

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https://scigraph.springernature.com/pub.10.1007/s00702-006-0507-5

19 September 2017

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The phosphorylation state of the microtubule-associated protein tau as affected by glutamate, colchicine and beta-amyloid in primary rat cortical neuronal cultures

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Mechanisms of beta-amyloid neurotoxicity: perspectives of pharmacotherapy

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Amyloid beta-protein and the genetics of Alzheimer's disease

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Calpain activation in neurodegenerative diseases: confocal immunofluorescence study with antibodies specifically recognizing the active form of calpain 2.

21 January 2018

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12 December 2020

Alzheimer's amyloid-beta peptide inhibits sodium/calcium exchange measured in rat and human brain plasma membrane vesicles.

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12 December 2020

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

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12 December 2020

Modulation of Ca2+ channel currents in primary cultures of rat cortical neurones by amyloid beta protein (1-40) is dependent on solubility status

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12 December 2020

Calpain inhibitors reduce depolarization induced loss of tau protein in primary septo-hippocampal cultures

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12 December 2020

Implants containing beta-amyloid protein are not neurotoxic to young and old rat brain

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12 December 2020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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12 December 2020

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

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12 December 2020

Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease

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12 December 2020

Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species.

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12 December 2020

Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofibrillary degeneration: sequestration of microtubule-associated proteins 1 and 2 and the disassembly of microtubules by the abnormal tau

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12 December 2020

Tau aggregation into fibrillar polymers: taupathies

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12 December 2020

[Effect of calpain on the degradation of tau protein in rat brain cortex extracts]

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12 December 2020

Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta

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12 December 2020

Beta/A4-evoked degeneration of differentiated SH-SY5Y human neuroblastoma cells

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12 December 2020

Amyloid beta peptide induces tau phosphorylation and loss of cholinergic neurons in rat primary septal cultures

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12 December 2020

Identification and localization of a tau peptide to paired helical filaments of Alzheimer disease

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12 December 2020

Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease

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12 December 2020

Tau cleavage and dephosphorylation in cerebellar granule neurons undergoing apoptosis

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12 December 2020

Purification, ultrastructure, and chemical analysis of Alzheimer disease amyloid plaque core protein

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12 December 2020

Neurotoxicity induced by amyloid beta-peptide and ibotenic acid in organotypic hippocampal cultures: protection by S-allyl-L-cysteine, a garlic compound

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12 December 2020

Lack of Alzheimer pathology after beta-amyloid protein injections in rat brain.

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12 December 2020

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

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12 December 2020

The role of Abeta peptides in Alzheimer's disease

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12 December 2020

Amyloids beta40 and beta42 are generated intracellularly in cultured human neurons and their secretion increases with maturation

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12 December 2020

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

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12 December 2020

Proteolysis of tau by calpain.

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12 December 2020

Different tau epitopes define Abeta42-mediated tau insolubility

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12 December 2020

beta-amyloid neurotoxicity is mediated by a glutamate-triggered excitotoxic cascade in rat nucleus basalis

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12 December 2020

Beta-amyloid-induced neurotoxicity of a hybrid septal cell line associated with increased tau phosphorylation and expression of beta-amyloid precursor protein

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12 December 2020

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

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12 December 2020

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

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12 December 2020

Melatonin attenuates beta-amyloid-induced inhibition of neurofilament expression

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12 December 2020

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

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12 December 2020

beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.

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12 December 2020

Free radicals in the neurotoxic actions of beta-amyloid.

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12 December 2020

Suppression of cyclin-dependent kinase 5 activation by amyloid precursor protein: a novel excitoprotective mechanism involving modulation of tau phosphorylation.

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12 December 2020

10.1007/S00702-006-0507-5

Identifiers

DOI

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Dimensions Publication ID

19 September 2017

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