The DNA damage response--repair or despair? (Q37785502)

23 August 2017

The DNA damage response--repair or despair? (English)

1 reference

23 August 2017

0 references

Mats Ljungman

1

1 reference

23 August 2017

1 October 2010

1 reference

Environmental and Molecular Mutagenesis

23 August 2017

1 reference

23 August 2017

51

1 reference

23 August 2017

8-9

1 reference

23 August 2017

879-889

1 reference

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

23 August 2017

1 reference

Activation of DNA damage signaling

21 January 2018

1 reference

The tumor suppressor p53 can both stimulate and inhibit ultraviolet light-induced apoptosis

21 January 2018

1 reference

Somatic Cells Efficiently Join Unrelated DNA Segments End-to-End

21 January 2018

1 reference

Phosphorylation of HuR by Chk2 regulates SIRT1 expression

21 January 2018

1 reference

7 January 2021

p53 and DNA damage-inducible expression of the xeroderma pigmentosum group C gene

1 reference

7 January 2021

The N-terminal domain of the Drosophila retinoblastoma protein Rbf1 interacts with ORC and associates with chromatin in an E2F independent manner

1 reference

7 January 2021

ATR kinase is required for global genomic nucleotide excision repair exclusively during S phase in human cells

1 reference

7 January 2021

MCM proteins: DNA damage, mutagenesis and repair

1 reference

7 January 2021

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

1 reference

7 January 2021

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

1 reference

7 January 2021

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

1 reference

7 January 2021

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2

1 reference

7 January 2021

Isolation and identification of the irradiation product of thymine

1 reference

7 January 2021

Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1.

1 reference

7 January 2021

UV-Induced stabilization of c-fos and other short-lived mRNAs

1 reference

7 January 2021

RELEASE OF ULTRAVIOLET LIGHT-INDUCED THYMINE DIMERS FROM DNA IN E. COLI K-12.

1 reference

7 January 2021

Regulation of protein synthesis by ionizing radiation.

1 reference

7 January 2021

Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

1 reference

7 January 2021

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

1 reference

7 January 2021

ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones.

1 reference

7 January 2021

Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics

1 reference

7 January 2021

Defective Repair Replication of DNA in Xeroderma Pigmentosum

1 reference

7 January 2021

Apoptosis and cancer: the genesis of a research field

1 reference

7 January 2021

Premature aging in mice deficient in DNA repair and transcription

1 reference

7 January 2021

RPA and ATR link transcriptional stress to p53

1 reference

7 January 2021

Psoralen-induced DNA interstrand cross-links block transcription and induce p53 in an ataxia-telangiectasia and rad3-related-dependent manner

1 reference

7 January 2021

Reactivation of ultra-violet-inactivated bacteriophage by visible light

1 reference

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

7 January 2021

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

1 reference

7 January 2021

Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance

1 reference

7 January 2021

Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts

1 reference

7 January 2021

DNA damage-inducible transcripts in mammalian cells

1 reference

7 January 2021

Trading places: how do DNA polymerases switch during translesion DNA synthesis?

1 reference

7 January 2021

Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity

1 reference

7 January 2021

Indirect ultraviolet-reactivation of phage lambda

1 reference

7 January 2021

ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin

1 reference

7 January 2021

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

1 reference

7 January 2021

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

1 reference

7 January 2021

The role of p53 in determining sensitivity to radiotherapy

1 reference

7 January 2021

Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts

1 reference

7 January 2021

H2AX phosphorylation after UV irradiation is triggered by DNA repair intermediates and is mediated by the ATR kinase.

1 reference

7 January 2021

Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint

1 reference

7 January 2021

DNA repair pathways as targets for cancer therapy

1 reference

7 January 2021

DNA damage-induced gene expression: signal transduction and relation to growth factor signaling

1 reference

7 January 2021

DNA Damage, Aging, and Cancer

1 reference

7 January 2021

A mechanism for gene conversion in fungi

1 reference

7 January 2021

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

1 reference

7 January 2021

Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair

1 reference

7 January 2021

The DNA-damage response in human biology and disease

1 reference

7 January 2021

An adaptive response of E. coli to low levels of alkylating agent: Comparison with previously characterised DNA repair pathways

1 reference

7 January 2021

Mismatch repair defects in cancer

1 reference

7 January 2021

Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta

1 reference

7 January 2021

Effect of ultraviolet inactivation and photoreactivation on the induced synthesis of β-galactosidase by Escherichia coli

1 reference

7 January 2021

[Metabolism of nucleic acids by E. coli B after ultraviolet irradiation]

1 reference

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

7 January 2021

Effect of Visible Light on the Recovery of Streptomyces Griseus Conidia from Ultra-violet Irradiation Injury

1 reference

7 January 2021

Radiation-induced gene translation profiles reveal tumor type and cancer-specific components

1 reference

7 January 2021

p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint

1 reference

7 January 2021

Posttranscriptional derepression of GADD45alpha by genotoxic stress.

1 reference

7 January 2021

T antigen is bound to a host protein in SY40-transformed cells

1 reference

7 January 2021

An N -Glycosidase from Escherichia coli That Releases Free Uracil from DNA Containing Deaminated Cytosine Residues

1 reference

7 January 2021

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1 reference

7 January 2021

Targeting the DNA damage response in cancer

1 reference

7 January 2021

Localized torsional tension in the DNA of human cells

1 reference

7 January 2021

Presence of negative torsional tension in the promoter region of the transcriptionally poised dihydrofolate reductase gene in vivo

1 reference

7 January 2021

Transcription - guarding the genome by sensing DNA damage

1 reference

7 January 2021

Inhibition of RNA polymerase II as a trigger for the p53 response

1 reference

7 January 2021

Induction of ser15 and lys382 modifications of p53 by blockage of transcription elongation.

1 reference

7 January 2021

Multiple mutations and cancer

1 reference

7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

7 January 2021

Atm-haploinsufficiency enhances susceptibility to carcinogen-induced mammary tumors

1 reference

7 January 2021

Radiation-induced changes in gene expression involve recruitment of existing messenger RNAs to and away from polysomes.

1 reference

7 January 2021

Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

1 reference

7 January 2021

Failure of ultraviolet-irradiated Escherichia coli to produce a cross-reacting protein

1 reference

7 January 2021

Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity

1 reference

7 January 2021

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

1 reference

7 January 2021

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

1 reference

7 January 2021

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

1 reference

7 January 2021

Role for p53 in the recovery of transcription and protection against apoptosis induced by ultraviolet light

1 reference

7 January 2021

Ultraviolet light-induced apoptosis is associated with S-phase in primary human fibroblasts.

1 reference

7 January 2021

P53 plays a protective role against UV- and cisplatin-induced apoptosis in transcription-coupled repair proficient fibroblasts.

1 reference

7 January 2021

Regulation of ultraviolet light-induced gene expression by gene size

1 reference

7 January 2021

Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

1 reference

7 January 2021

ARTIFICIAL TRANSMUTATION OF THE GENE

1 reference

7 January 2021

DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation.

1 reference

7 January 2021

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

1 reference

7 January 2021

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair

1 reference

7 January 2021

DNA damage-induced apoptosis

1 reference

7 January 2021

Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island

1 reference

7 January 2021

EVIDENCE FOR REPAIR-REPLICATION OF ULTRAVIOLET DAMAGED DNA IN BACTERIA

1 reference

7 January 2021

MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response

1 reference

7 January 2021

Early embryonic lethality due to targeted inactivation of DNA ligase III

1 reference

7 January 2021

EVIDENCE FOR REPAIR OF ULTRA-VIOLET DAMAGED DEOXYRIBONUCLEIC ACID IN CULTURED MAMMALIAN CELLS.

1 reference

7 January 2021

Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2.

1 reference

7 January 2021

Photoreactivation in vitro of ultraviolet-inactivated Hemophilus influenzae transforming factor

1 reference

7 January 2021

Discontinuities in the DNA synthesized in an Excision-defective strain of Escherichia coli following ultraviolet irradiation

1 reference

7 January 2021

A new pathway for DNA repair in Escherichia coli

1 reference

7 January 2021

Gene and transcription unit mapping by radiation effects

1 reference

7 January 2021

THE DISAPPEARANCE OF THYMINE DIMERS FROM DNA: AN ERROR-CORRECTING MECHANISM

1 reference

7 January 2021

Checkpoint kinase ATR promotes nucleotide excision repair of UV-induced DNA damage via physical interaction with xeroderma pigmentosum group A.

1 reference

7 January 2021

RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript

1 reference

7 January 2021

Ionizing radiation-induced oxidative stress alters miRNA expression

1 reference

7 January 2021

Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer.

1 reference

7 January 2021

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

1 reference

7 January 2021

Cancer risks and mortality in heterozygous ATM mutation carriers

1 reference

7 January 2021

A role for ATR in the DNA damage-induced phosphorylation of p53

1 reference

7 January 2021

Distinct mechanisms act in concert to mediate cell cycle arrest

1 reference

7 January 2021

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

1 reference

7 January 2021

Cancer susceptibility and the functions of BRCA1 and BRCA2

1 reference

7 January 2021

Repair tracts in mismatched DNA heteroduplexes

1 reference

7 January 2021

Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

1 reference

7 January 2021

HuR regulates p21 mRNA stabilization by UV light

1 reference

7 January 2021

Genetical Implications of the Structure of Deoxyribonucleic Acid

1 reference

7 January 2021

Segregation of transcription and replication sites into higher order domains

1 reference

7 January 2021

Thermal Enhancement of Ultraviolet Mutability in a tif-1 uvrA Derivative of Escherichia coli B/r: Evidence That Ultraviolet Mutagenesis Depends upon an Inducible Function

1 reference

7 January 2021

ATR-dependent checkpoint modulates XPA nuclear import in response to UV irradiation

1 reference

7 January 2021

The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

1 reference

7 January 2021

RAP80 and RNF8, key players in the recruitment of repair proteins to DNA damage sites

1 reference

7 January 2021

Nucleolin links to arsenic-induced stabilization of GADD5alpha mRNA

1 reference

7 January 2021

Identifiers

DOI

10.1002/EM.20597

1 reference

23 August 2017

1 reference

PubMed ID

20818630