Psoralen-induced DNA interstrand cross-links block transcription and induce p53 in an ataxia-telangiectasia and rad3-related-dependent manner (Q34601470)

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English	Psoralen-induced DNA interstrand cross-links block transcription and induce p53 in an ataxia-telangiectasia and rad3-related-dependent manner	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

3 August 2017

Psoralen-induced DNA interstrand cross-links block transcription and induce p53 in an ataxia-telangiectasia and rad3-related-dependent manner (English)

1 reference

Europe PubMed Central

3 August 2017

author name string

Frederick A Derheimer

1

1 reference

Europe PubMed Central

3 August 2017

J Kevin Hicks

2

1 reference

Europe PubMed Central

3 August 2017

Michelle T Paulsen

3

1 reference

Europe PubMed Central

3 August 2017

Christine E Canman

4

1 reference

Europe PubMed Central

3 August 2017

Mats Ljungman

5

1 reference

Europe PubMed Central

3 August 2017

publication date

8 December 2008

1 reference

Europe PubMed Central

3 August 2017

Molecular Pharmacology

1 reference

Europe PubMed Central

3 August 2017

75

1 reference

Europe PubMed Central

3 August 2017

599-607

1 reference

Europe PubMed Central

3 August 2017

3

1 reference

Europe PubMed Central

3 August 2017

Mechanism of replication-coupled DNA interstrand crosslink repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

DNA polymerase eta reduces the gamma-H2AX response to psoralen interstrand crosslinks in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Central role of mitochondria and p53 in PUVA-induced apoptosis in human keratinocytes cell line NCTC-2544.

1 reference

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7 July 2018

RPA and ATR link transcriptional stress to p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Avoiding and resolving conflicts between DNA replication and transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Senescence of human fibroblasts after psoralen photoactivation is mediated by ATR kinase and persistent DNA damage foci at telomeres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Post-translational modification of p53 in tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells

1 reference

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7 July 2018

Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Ultraviolet light-induced apoptosis is associated with S-phase in primary human fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

The DNA damage signal for Mdm2 regulation, Trp53 induction, and sunburn cell formation in vivo originates from actively transcribed genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

The role of PUVA in the treatment of psoriasis. Photobiology issues related to skin cancer incidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

DNA replication is required To elicit cellular responses to psoralen-induced DNA interstrand cross-links.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

ATR disruption leads to chromosomal fragmentation and early embryonic lethality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

PUVA inhibits DNA replication, but not gene transcription at nonlethal dosages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Persistent DNA damage induced by ultraviolet light inhibits p21waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Prolonged p53 protein accumulation in trichothiodystrophy fibroblasts dependent on unrepaired pyrimidine dimers on the transcribed strands of cellular genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Cutaneous squamous-cell carcinoma in patients treated with PUVA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Thermal denaturation of DNA for immunochemical staining of incorporated bromodeoxyuridine (BrdUrd): critical factors that affect the amount of fluorescence and the shape of BrdUrd/DNA histogram

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Psoralens as photoactive probes of nucleic acid structure and function: organic chemistry, photochemistry, and biochemistry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Impairment of RNA synthesis and its recovery in angelicin photosensitized mammalian cells. A probe for DNA damage and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Photochemistry and photobiology of psoralens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

7 July 2018

Efficient NES-dependent protein nuclear export requires ongoing synthesis and export of mRNAs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

26 October 2018

Phosphorylation and nuclear accumulation are distinct events contributing to the activation of p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

26 October 2018

Induction of DNA replication-mediated double strand breaks by psoralen DNA interstrand cross-links

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

26 October 2018

ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

26 October 2018

Induction of ser15 and lys382 modifications of p53 by blockage of transcription elongation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

26 October 2018

Processing of psoralen adducts in an active human gene: repair and replication of DNA containing monoadducts and interstrand cross-links

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684911

26 October 2018

Transcription - guarding the genome by sensing DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19064630

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light

1 reference

https://pubmed.ncbi.nlm.nih.gov/19064630

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA repair in human cells containing photoadducts of 8-methoxypsoralen or angelicin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19064630

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

U.v.-induced nuclear accumulation of p53 is evoked through DNA damage of actively transcribed genes independent of the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/19064630

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockage of RNA polymerase as a possible trigger for u.v. light-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19064630

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of RNA polymerase II as a trigger for the p53 response

1 reference

https://pubmed.ncbi.nlm.nih.gov/19064630

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-dependent effects of DNA-damaging agents on p53-mediated cell cycle arrest

1 reference

https://pubmed.ncbi.nlm.nih.gov/19064630

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/MOL.108.051698

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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