Endoplasmic reticulum aminopeptidases: Biology and pathogenic potential (Q37763503)

22 August 2017

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title

Endoplasmic reticulum aminopeptidases: Biology and pathogenic potential (English)

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22 August 2017

endoplasmic reticulum

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author name string

Nigil Haroon

series ordinal

1

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22 August 2017

Robert D Inman

series ordinal

2

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22 August 2017

language of work or name

English

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publication date

8 June 2010

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Nature Reviews Rheumatology

22 August 2017

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22 August 2017

6

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22 August 2017

461-467

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22 August 2017

8

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https://scigraph.springernature.com/pub.10.1038/nrrheum.2010.85

22 August 2017

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cites work

Endoplasmic reticulum aminopeptidase associated with antigen processing regulates quality of processed peptides presented by MHC class I molecules

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HLA-B27 misfolding in transgenic rats is associated with activation of the unfolded protein response.

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HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors.

21 January 2018

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Shedding of the type II IL-1 decoy receptor requires a multifunctional aminopeptidase, aminopeptidase regulator of TNF receptor type 1 shedding

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Identification of ARTS-1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain shedding

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Leukocyte receptor complex-encoded immunomodulatory receptors show differing specificity for alternative HLA-B27 structures.

21 January 2018

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Expression of endoplasmic reticulum aminopeptidases in EBV-B cell lines from healthy donors and in leukemia/lymphoma, carcinoma, and melanoma cell lines.

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Susceptibility to ankylosing spondylitis in twins the role of genes, HLA, and the environment

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Occurrence of ankylosing spondylitis in a nationwide series of twins

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Ankylosing spondylitis in Danish and Norwegian twins: occurrence and the relative importance of genetic vs. environmental effectors in disease causation.

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Ankylosing spondylitis and HL-A 27.

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Recurrence risk modelling of the genetic susceptibility to ankylosing spondylitis

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Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci

31 March 2020

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Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

31 March 2020

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Association of a specific ERAP1/ARTS1 haplotype with disease susceptibility in ankylosing spondylitis.

31 March 2020

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Association ofERAP1, but notIL23R, with ankylosing spondylitis in a Han Chinese population

31 March 2020

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ARTS1 polymorphisms are associated with ankylosing spondylitis in Koreans.

31 March 2020

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Investigating the genetic association between ERAP1 and ankylosing spondylitis

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Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis.

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Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidases

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The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a "molecular ruler" mechanism.

31 March 2020

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The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1.

31 March 2020

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Coping with loss of perfection in the MHC class I peptide repertoire

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An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

31 March 2020

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A genome-wide association study of global gene expression

31 March 2020

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ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

31 March 2020

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In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides.

31 March 2020

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The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues

31 March 2020

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Genome sequence of the Brown Norway rat yields insights into mammalian evolution

31 March 2020

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Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.

31 March 2020

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HLA-B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: Implications for the pathogenesis of spondylarthritis-like disease

31 March 2020

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HLA-B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with Th17 activation in transgenic rats

31 March 2020

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Interactions of HLA-B27 with the peptide loading complex as revealed by heavy chain mutations

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Recognition of classical and heavy chain forms of HLA-B27 by leukocyte receptors

31 March 2020

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Consistent patterns of expression of HLA class I free heavy chains in healthy individuals and raised expression in spondyloarthropathy patients point to physiological and pathological roles.

31 March 2020

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Interaction of HLA-B27 homodimers with KIR3DL1 and KIR3DL2, unlike HLA-B27 heterotrimers, is independent of the sequence of bound peptide

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.85

Cell-surface expression and immune receptor recognition of HLA-B27 homodimers

31 March 2020

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An Aminopeptidase, ARTS-1, Is Required for Interleukin-6 Receptor Shedding

31 March 2020

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Extracellular TNFR1 release requires the calcium-dependent formation of a nucleobindin 2-ARTS-1 complex

31 March 2020

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An association between RBMX, a heterogeneous nuclear ribonucleoprotein, and ARTS-1 regulates extracellular TNFR1 release

31 March 2020

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The interleukin-23/interleukin-17 axis in spondyloarthritis

31 March 2020

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Prospective meta-analysis of interleukin 1 gene complex polymorphisms confirms associations with ankylosing spondylitis

31 March 2020

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HLA-B27 misfolding and spondyloarthropathies.

31 March 2020

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HLA-B27 heavy chains contribute to spontaneous inflammatory disease in B27/human beta2-microglobulin (beta2m) double transgenic mice with disrupted mouse beta2m

31 March 2020

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The peptide binding specificity of HLA-B27 subtypes

31 March 2020

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Susceptibility to ankylosing spondylitis correlates with the C-terminal residue of peptides presented by various HLA-B27 subtypes

31 March 2020

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Molecular mimicry: any role in the pathogenesis of spondyloarthropathies?

31 March 2020

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Genetic risk factors in typical haemolytic uraemic syndrome

31 March 2020

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Identification of 33 polymorphisms in the adipocyte-derived leucine aminopeptidase (ALAP) gene and possible association with hypertension

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.85

Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.85

The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.85

Inadequate tolerance induction may induce pre-eclampsia

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.85

Inhibitory receptors sensing HLA-G1 molecules in pregnancy: decidua-associated natural killer cells express LIR-1 and CD94/NKG2A and acquire p49, an HLA-G1-specific receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.85

Possible roles of KIR2DL4 expression on uNK cells in human pregnancy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.85

Endoplasmic reticulum aminopeptidase-1 mediates leukemia inhibitory factor-induced cell surface human leukocyte antigen-G expression in JEG-3 choriocarcinoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.85

Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.85

Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.85

Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.85

Association of antigen processing machinery and HLA class I defects with clinicopathological outcome in cervical carcinoma

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.85

Genetic variation of antigen processing machinery components and association with cervical carcinoma

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.85

Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.85

The effect of mutant beta 2-microglobulins on the conformation of HLA-B27 detected by antibody and by CTL.

31 March 2020

1 reference

12 December 2020

Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences

1 reference

12 December 2020

Serum cytokine receptors in ankylosing spondylitis: relationship to inflammatory markers and endoplasmic reticulum aminopeptidase polymorphisms

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12 December 2020

Association of candidate gene polymorphisms with bone mineral density in community-dwelling Japanese women and men

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12 December 2020

Free HLA class I heavy chain-carrying monocytes--a potential role in the pathogenesis of spondyloarthropathies

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12 December 2020

Association of IL23R and ERAP1 genes with ankylosing spondylitis in a Portuguese population.

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12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2010.85

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Dimensions Publication ID

22 August 2017

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