An Aminopeptidase, ARTS-1, Is Required for Interleukin-6 Receptor Shedding (Q24301863)

https://api.crossref.org/works/10.1074/JBC.M300456200

2 January 2024

main subject

interleukins

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Interleukin 6 receptor

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Endoplasmic reticulum aminopeptidase 1

GOA release 2020-03-11

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regulation of innate immune response

GOA release 2020-03-11

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GOA release 2020-03-11

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https://api.crossref.org/works/10.1074/JBC.M300456200

2 January 2024

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https://api.crossref.org/works/10.1074/JBC.M300456200

2 January 2024

author name string

Xinle Cui

1

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Feras Hawari

3

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Farshid N. Rouhani

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12748171

2 January 2024

Stewart J. Levine

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12748171

2 January 2024

language of work or name

English

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publication date

1 August 2003

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14 May 2003

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12748171

full work available at URL

2 January 2024

http://www.jbc.org/article/S0021925820843609/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12748171

https://api.elsevier.com/content/article/PII:S0021925820843609?httpAccept=text/xml

2 January 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M300456200

https://api.elsevier.com/content/article/PII:S0021925820843609?httpAccept=text/plain

2 January 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M300456200

https://syndication.highwire.org/content/doi/10.1074/jbc.M300456200

2 January 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M300456200

Journal of Biological Chemistry

2 January 2024

published in

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volume

278

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page(s)

28677-85

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issue

31

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cites work

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C-reactive protein: a physiological activator of interleukin 6 receptor shedding.

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Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

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The conserved box 1 motif of cytokine receptors is required for association with JAK kinases

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Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

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Shedding of the interleukin-6 (IL-6) receptor (gp80) determines the ability of IL-6 to induce gp130 phosphorylation in human osteoblasts

21 January 2018

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Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

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Chemotactic agents induce IL-6Ralpha shedding from polymorphonuclear cells: involvement of a metalloproteinase of the TNF-alpha-converting enzyme (TACE) type

21 January 2018

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The soluble interleukin-6 receptor is generated by shedding

21 January 2018

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Soluble interleukin-6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism

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Shedding of interleukin-6 receptor and tumor necrosis factor alpha. Contribution of the stalk sequence to the cleavage pattern of transmembrane proteins

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Human myeloma cells shed the interleukin-6 receptor: inhibition by tissue inhibitor of metalloproteinase-3 and a hydroxamate-based metalloproteinase inhibitor.

21 January 2018

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Genomic organization of the human adipocyte-derived leucine aminopeptidase gene and its relationship to the placental leucine aminopeptidase/oxytocinase gene

21 January 2018

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Zinc coordination, function, and structure of zinc enzymes and other proteins

21 January 2018

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Production of homozygous mutant ES cells with a single targeting construct

21 January 2018

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Histidine residue in the zinc-binding motif of aminopeptidase A is critical for enzymatic activity

21 January 2018

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MEROPS: the protease database

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ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

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Molecular cloning of adipocyte-derived leucine aminopeptidase highly related to placental leucine aminopeptidase/oxytocinase

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Characterization of recombinant human adipocyte-derived leucine aminopeptidase expressed in Chinese hamster ovary cells

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Molecular characterization of a puromycin-insensitive leucyl-specific aminopeptidase, PILS-AP

21 January 2018

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Identification of 33 polymorphisms in the adipocyte-derived leucine aminopeptidase (ALAP) gene and possible association with hypertension

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A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

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Remarkable roles of proteolysis on and beyond the cell surface

21 January 2018

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Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

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Differential Activation of Acute Phase Response Factor/STAT3 and STAT1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130

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IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation

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A soluble interleukin 6 receptor isolated from conditioned medium of human breast cancer cells is encoded by a differentially spliced mRNA

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A metalloproteinase inhibitor blocks the shedding of soluble cytokine receptors and processing of transmembrane cytokine precursors in human monocytic cells

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Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. I. Definition of a novel phosphotyrosine motif mediating STAT1 activation

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inferred from DOI database lookup

7 January 2021

based on heuristic

The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300456200

inferred from DOI database lookup

7 January 2021

based on heuristic

Cellular and Molecular Biology

3

47

583

Montero-Julian

2001

1 reference

https://api.crossref.org/works/10.1074/JBC.M300456200

IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses

2 January 2024

8

1 reference

https://api.crossref.org/works/10.1074/JBC.M300456200

Identification of ARTS-1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain shedding

2 January 2024

29

1 reference

https://api.crossref.org/works/10.1074/JBC.M300456200

2 January 2024

Identifiers

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