In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides. (Q53586381)

15 May 2018

title

In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides. (English)

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15 May 2018

author name string

Gianna Elena Hammer

1

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15 May 2018

Federico Gonzalez

2

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15 May 2018

Edward James

3

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15 May 2018

Hector Nolla

4

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15 May 2018

Nilabh Shastri

5

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15 May 2018

language of work or name

English

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publication date

26 November 2006

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15 May 2018

published in

Nature Immunology

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volume

8

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15 May 2018

page(s)

101-108

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issue

1

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15 May 2018

Producing nature's gene-chips: the generation of peptides for display by MHC class I molecules

cites work

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Mechanisms of MHC class I-restricted antigen processing and cross-presentation

21 January 2018

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All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen-processing pathway

21 January 2018

1 reference

The Group II Chaperonin TRiC Protects Proteolytic Intermediates from Degradation in the MHC Class I Antigen Processing Pathway

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1 reference

Hsp90alpha chaperones large C-terminally extended proteolytic intermediates in the MHC class I antigen processing pathway

21 January 2018

1 reference

Post-proteasomal antigen processing for major histocompatibility complex class I presentation

21 January 2018

1 reference

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells

21 January 2018

1 reference

ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

21 January 2018

1 reference

The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues

21 January 2018

1 reference

The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules

21 January 2018

1 reference

In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules

21 January 2018

1 reference

Single H2Kb, H2Db and double H2KbDb knockout mice: peripheral CD8+ T cell repertoire and anti-lymphocytic choriomeningitis virus cytolytic responses

21 January 2018

1 reference

The molecular basis of allorecognition

21 January 2018

1 reference

Maternally transmitted histocompatibility antigen of mice: a hydrophobic peptide of a mitochondrially encoded protein

21 January 2018

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ER aminopeptidases generate a unique pool of peptides for MHC class I molecules.

21 January 2018

1 reference

The nature of the MHC class I peptide loading complex

21 January 2018

1 reference

Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance.

21 January 2018

1 reference

Beyond the proteasome: trimming, degradation and generation of MHC class I ligands by auxiliary proteases

21 January 2018

1 reference

Export of antigenic peptides from the endoplasmic reticulum intersects with retrograde protein translocation through the Sec61p channel

21 January 2018

1 reference

Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants

21 January 2018

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Quantitative and qualitative influences of tapasin on the class I peptide repertoire.

21 January 2018

1 reference

Generation of CD8+ T cells specific for transporter associated with antigen processing deficient cells.

21 January 2018

1 reference

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

21 January 2018

1 reference

An alternative open reading frame of the human macrophage colony-stimulating factor gene is independently translated and codes for an antigenic peptide of 14 amino acids recognized by tumor-infiltrating CD8 T lymphocytes

21 January 2018

1 reference

Potent T cell response to a class I-binding 13-mer viral epitope and the influence of HLA micropolymorphism in controlling epitope length

21 January 2018

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Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle

21 January 2018

1 reference

Conformational restraints and flexibility of 14-meric peptides in complex with HLA-B*3501.

21 January 2018

1 reference

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide

21 January 2018

1 reference

Three-dimensional structure of a peptide extending from one end of a class I MHC binding site

21 January 2018

1 reference

The immunogenomics of minor histocompatibility antigens.

21 January 2018

1 reference

The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation

21 January 2018

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Brefeldin A specifically inhibits presentation of protein antigens to cytotoxic T lymphocytes

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NI1409

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15 May 2018

PubMed ID

17128277

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15 May 2018