The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1. (Q33382992)

26 July 2017

The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1. (English)

1 reference

26 July 2017

Shih-Chung Chang

6

0 references

Athanasios Papakyriakou

object named as

Athanasios Papakyriakou

3

0 references

Efstratios Stratikos

object named as

Efstratios Stratikos

8

0 references

author name string

Irini Evnouchidou

1

1 reference

26 July 2017

Frank Momburg

2

1 reference

26 July 2017

Angeliki Chroni

4

1 reference

26 July 2017

Leondios Leondiadis

5

1 reference

26 July 2017

Alfred L Goldberg

7

1 reference

26 July 2017

language of work or name

English

0 references

publication date

6 November 2008

1 reference

26 July 2017

1 reference

26 July 2017

3

1 reference

26 July 2017

e3658

1 reference

26 July 2017

11

1 reference

Creative Commons Attribution 4.0 International

26 July 2017

start time

6 November 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum

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21 June 2018

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The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a "molecular ruler" mechanism.

21 June 2018

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Crystal structures of the tricorn interacting factor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations

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The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation

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The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues

21 June 2018

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An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

21 June 2018

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ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

21 June 2018

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The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides.

21 June 2018

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Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase

21 June 2018

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26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide

21 June 2018

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Antigen processing by the proteasome

21 June 2018

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Cut and trim: generating MHC class I peptide ligands

21 June 2018

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Molecular characterization of a puromycin-insensitive leucyl-specific aminopeptidase, PILS-AP

21 June 2018

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Characterization of a recombinant soluble form of human placental leucine aminopeptidase/oxytocinase expressed in Chinese hamster ovary cells

21 June 2018

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The proteasome: a macromolecular assembly designed for controlled proteolysis

21 June 2018

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Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells

21 June 2018

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Degradation of cell proteins and the generation of MHC class I-presented peptides

21 June 2018

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Molecular cloning of adipocyte-derived leucine aminopeptidase highly related to placental leucine aminopeptidase/oxytocinase

21 June 2018

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21 June 2018

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21 June 2018

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Peptide size selection by the major histocompatibility complex-encoded peptide transporter

21 June 2018

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21 June 2018

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Trimming of TAP-translocated peptides in the endoplasmic reticulum and in the cytosol during recycling

21 June 2018

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Analysis of the fine specificity of rat, mouse and human TAP peptide transporters

21 June 2018

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Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.

21 June 2018

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The final cut: how ERAP1 trims MHC ligands to size

21 January 2018

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The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules

21 January 2018

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In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides.

21 January 2018

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The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/18987748

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of endoplasmic reticulum-associated aminopeptidase 1 in immunity to infection and in cross-presentation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18987748

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Simulated interactions between angiotensin-converting enzyme and substrate gonadotropin-releasing hormone: novel insights into domain selectivity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18987748

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0003658

1 reference

26 July 2017

0 references

1 reference

26 July 2017

1 reference