Quantification of transthyretin kinetic stability in human plasma using subunit exchange. (Q37688196)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661308%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Quantification of transthyretin kinetic stability in human plasma using subunit exchange (English)

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12 March 2020

10

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12 March 2020

Marta Novais

3

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12 March 2020

Gregory M Solis

5

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R. Luke Wiseman

6

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Jeffery W Kelly

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12 March 2020

author name string

Irit Rappley

1

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Cecília Monteiro

2

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12 March 2020

Aleksandra Baranczak

4

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12 March 2020

Stephen Helmke

7

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12 March 2020

Mathew S Maurer

8

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12 March 2020

Teresa Coelho

9

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language of work or name

English

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publication date

24 March 2014

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12 March 2020

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12 March 2020

volume

53

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12 March 2020

issue

12

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12 March 2020

page(s)

1993-2006

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Repurposing diflunisal for familial amyloid polyneuropathy: a randomized clinical trial

12 March 2020

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A stilbene that binds selectively to transthyretin in cells and remains dark until it undergoes a chemoselective reaction to create a bright blue fluorescent conjugate

23 August 2017

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23 August 2017

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Orally administered diflunisal stabilizes transthyretin against dissociation required for amyloidogenesis

23 August 2017

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23 August 2017

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The pathway by which the tetrameric protein transthyretin dissociates.

23 August 2017

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23 August 2017

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New insights into the mechanisms of protein misfolding and aggregation in amyloidogenic diseases derived from pressure studies

23 August 2017

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A peculiar form of peripheral neuropathy; familiar atypical generalized amyloidosis with special involvement of the peripheral nerves

23 August 2017

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23 August 2017

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Benzoxazoles as transthyretin amyloid fibril inhibitors: synthesis, evaluation, and mechanism of action

23 August 2017

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Prevention of transthyretin amyloid disease by changing protein misfolding energetics.

23 August 2017

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Sequence-dependent denaturation energetics: A major determinant in amyloid disease diversity

23 August 2017

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The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis

23 August 2017

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23 August 2017

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An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured

23 August 2017

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Transthyretin slowly exchanges subunits under physiological conditions: A convenient chromatographic method to study subunit exchange in oligomeric proteins.

23 August 2017

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23 August 2017

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The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid

23 August 2017

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Structure of a complex of two plasma proteins: transthyretin and retinol-binding protein

23 August 2017

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23 August 2017

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Fibril in senile systemic amyloidosis is derived from normal transthyretin

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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6 September 2017

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L55P transthyretin accelerates subunit exchange and leads to rapid formation of hybrid tetramers.

6 September 2017

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The most pathogenic transthyretin variant, L55P, forms amyloid fibrils under acidic conditions and protofilaments under physiological conditions

23 June 2018

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The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways

23 June 2018

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The evolution of gene expression, structure and function of transthyretin

23 June 2018

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Comparison of lethal and nonlethal transthyretin variants and their relationship to amyloid disease

23 June 2018

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Persistent organic pollutants and transthyretin-bound thyroxin in plasma of Inuit women of childbearing age.

23 June 2018

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Genetic stabilization of transthyretin, cerebrovascular disease, and life expectancy.

1 September 2018

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Retinol and retinol-binding protein stabilize transthyretin via formation of retinol transport complex

1 September 2018

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Structure and intermolecular dynamics of aggregates populated during amyloid fibril formation studied by hydrogen/deuterium exchange.

1 September 2018

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Trapping the monomer of a non-amyloidogenic variant of transthyretin: exploring its possible use as a therapeutic strategy against transthyretin amyloidogenic diseases.

1 September 2018

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C-Terminal truncation affects subunit exchange of human alphaA-crystallin with alphaB-crystallin.

1 September 2018

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Kinetic stabilization of an oligomeric protein under physiological conditions demonstrated by a lack of subunit exchange: implications for transthyretin amyloidosis.

1 September 2018

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Kinetic stabilization of the native state by protein engineering: implications for inhibition of transthyretin amyloidogenesis

1 September 2018

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Transthyretin aggregation under partially denaturing conditions is a downhill polymerization

1 September 2018

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Native state stabilization by NSAIDs inhibits transthyretin amyloidogenesis from the most common familial disease variants

1 September 2018

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Screening transthyretin amyloid fibril inhibitors: characterization of novel multiprotein, multiligand complexes by mass spectrometry

1 September 2018

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Anion shielding of electrostatic repulsions in transthyretin modulates stability and amyloidosis: insight into the chaotrope unfolding dichotomy

1 September 2018

1 reference

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Protein subunit interactions and structural integrity of amyloidogenic transthyretins: evidence from electrospray mass spectrometry.

1 September 2018

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Tabulation of human transthyretin (TTR) variants, 2003

1 September 2018

1 reference

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METABOLISM OF IODINE-131--LABELED THYROXINE-BINDING PREALBUMIN IN MAN

3 December 2018

1 reference

12 December 2020

Discovering transthyretin amyloid fibril inhibitors by limited screening

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12 December 2020

Cardiac amyloidosis: a treatable disease, often overlooked

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12 December 2020

Sequence Communication: Tabulation of transthyretin (TTR) variants as of 1/1/2000

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12 December 2020

Clusterin is an extracellular chaperone that specifically interacts with slowly aggregating proteins on their off-folding pathway

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12 December 2020

Clusterin Has Chaperone-like Activity Similar to That of Small Heat Shock Proteins

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12 December 2020

Identifiers

DOI

10.1021/BI500171J

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661308%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661308%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661308%20AND%20SRC:MED&resulttype=core&format=json