Screening transthyretin amyloid fibril inhibitors: characterization of novel multiprotein, multiligand complexes by mass spectrometry (Q44022725)

29 November 2017

Screening transthyretin amyloid fibril inhibitors: characterization of novel multiprotein, multiligand complexes by mass spectrometry (English)

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29 November 2017

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Jeffery W Kelly

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29 November 2017

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Carol V Robinson

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Hans E Purkey

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29 November 2017

Margaret G McCammon

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29 November 2017

Catherine A Keetch

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29 November 2017

Lesley H Greene

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29 November 2017

H Michael Petrassi

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29 November 2017

1 June 2002

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29 November 2017

851-863

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describes a project that uses

29 November 2017

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Amyloid diseases: abnormal protein aggregation in neurodegeneration

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Amyloid fibril formation and protein misassembly: a structural quest for insights into amyloid and prion diseases

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Clinical improvement after liver transplantation for type I familial amyloid polyneuropathy

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

A comparative analysis of 23 structures of the amyloidogenic protein transthyretin

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Comparison of lethal and nonlethal transthyretin variants and their relationship to amyloid disease

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Computer graphics in drug design: molecular modeling of thyroid hormone-prealbumin interactions

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Inhibiting transthyretin amyloid fibril formation via protein stabilization

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Inhibiting transthyretin conformational changes that lead to amyloid fibril formation

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Discovering transthyretin amyloid fibril inhibitors by limited screening

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Electrospray ionization mass spectrometry in the study of biomolecular non-covalent interactions

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Analysis of transcription complexes and effects of ligands by microelectrospray ionization mass spectrometry

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Mass spectrometry as a novel approach to probe cooperativity in multimeric enzymatic systems

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Protein subunit interactions and structural integrity of amyloidogenic transthyretins: evidence from electrospray mass spectrometry.

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Dissection of multi-protein complexes using mass spectrometry: Subunit interactions in transthyretin and retinol-binding protein complexes

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Carbonic Anhydrase-Inhibitor Binding: From Solution to the Gas Phase

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Specificity and interactions of the protein OppA: partitioning solvent binding effects using mass spectrometry 1 1Edited by P. E. Wright

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Effects of anions on the positive ion electrospray ionization mass spectra of peptides and proteins

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits*

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

The structure of human retinol-binding protein (RBP) with its carrier protein transthyretin reveals an interaction with the carboxy terminus of RBP

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

The interaction between retinol-binding proteins and prealbumins studied by fluorescence polarization

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Synthesis and evaluation of inhibitors of transthyretin amyloid formation based on the non-steroidal anti-inflammatory drug, flufenamic acid

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Rational design of potent human transthyretin amyloid disease inhibitors

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

The transthyretin-retinol-binding protein complex

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

The crystal structure of amyloidogenic Leu55 --> Pro transthyretin variant reveals a possible pathway for transthyretin polymerization into amyloid fibrils

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Arresting amyloidosis in vivo using small-molecule anionic sulphonates or sulphates: implications for Alzheimer's disease.

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Fenchylamine sulfonamide inhibitors of amyloid beta peptide production by the gamma-secretase proteolytic pathway: potential small-molecule therapeutic agents for the treatment of Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Controlling polymerization of beta-amyloid and prion-derived peptides with synthetic small molecule ligands.

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Role of conserved residues in structure and stability: Tryptophans of human serum retinol-binding protein, a model for the lipocalin superfamily

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties

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https://api.crossref.org/works/10.1016%2FS0969-2126%2802%2900771-2

7 January 2021

10.1016/S0969-2126(02)00771-2

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DOI

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29 November 2017

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