Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis (Q27734827)

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V Bellotti

3

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C V Robinson

4

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W L Hutchinson

5

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P E Fraser

6

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P N Hawkins

7

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C M Dobson

8

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C C Blake

10

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M B Pepys

11

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language of work or name

English

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publication date

27 February 1997

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published in

Nature

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volume

385

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page(s)

787-93

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issue

6619

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7 January 2021

Amyloid deposits and amyloidosis. The beta-fibrilloses (first of two parts).

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7 January 2021

Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibril is a continuous β-sheet helix

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7 January 2021

Fibril formation by primate, rodent, and Dutch-hemorrhagic analogues of Alzheimer amyloid beta-protein

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7 January 2021

Synthetic peptides corresponding to different mutated regions of the amyloid gene in familial Creutzfeldt-Jakob disease show enhanced in vitro formation of morphologically different amyloid fibrils

1 reference

7 January 2021

Increased body temperature accelerates aggregation of the Leu-68-->Gln mutant cystatin C, the amyloid-forming protein in hereditary cystatin C amyloid angiopathy.

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7 January 2021

A role for destabilizing amino acid replacements in light-chain amyloidosis

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7 January 2021

Fibril formation from recombinant human serum amyloid A.

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7 January 2021

Comparison of lethal and nonlethal transthyretin variants and their relationship to amyloid disease

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7 January 2021

Structural model for the beta-amyloid fibril based on interstrand alignment of an antiparallel-sheet comprising a C-terminal peptide

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7 January 2021

Alternative conformations of amyloidogenic proteins govern their behavior

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7 January 2021

Hereditary hepatic and systemic amyloidosis caused by a new deletion/insertion mutation in the apolipoprotein AI gene

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7 January 2021

Human lysozyme gene mutations cause hereditary systemic amyloidosis

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7 January 2021

Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 Å Resolution

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7 January 2021

X-ray studies of water in crystals of lysozyme

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7 January 2021

Refinement of human lysozyme at 1.5 A resolution analysis of non-bonded and hydrogen-bond interactions

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7 January 2021

Lysozyme and alpha-lactalbumin: structure, function, and interrelationships

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7 January 2021

The folding of hen lysozyme involves partially structured intermediates and multiple pathways

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7 January 2021

Insights into Protein Folding Using Physical Techniques: Studies of Lysozyme and $\alpha $ -lactalbumin

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7 January 2021

The molten globule state as a clue for understanding the folding and cooperativity of globular-protein structure.

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7 January 2021

Electrospray ionization for mass spectrometry of large biomolecules

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7 January 2021

Thermal stability determinants of chicken egg-white lysozyme core mutants: hydrophobicity, packing volume, and conserved buried water molecules

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7 January 2021

'Fragile' liver and massive hepatic haemorrhage due to hereditary amyloidosis

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7 January 2021

Incorporation of glutamine repeats makes protein oligomerize: implications for neurodegenerative diseases

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7 January 2021

Isolation and characterization of the integral glycosaminoglycan constituents of human amyloid A and monoclonal light-chain amyloid fibrils.

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7 January 2021

An equilibrium partially folded state of human lysozyme at low pH

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7 January 2021

Bipartite structure of the alpha-lactalbumin molten globule

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7 January 2021

Kinetic Consequences of the Removal of a Disulfide Bridge on the Folding of Hen Lysozyme

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7 January 2021

Conformation of GroEL-bound alpha-lactalbumin probed by mass spectrometry.

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7 January 2021

Far-UV Circular Dichroism Reveals a Conformational Switch in a Peptide Fragment from the .beta.-Sheet of Hen Lysozyme

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7 January 2021

Context-dependent secondary structure formation of a designed protein sequence

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7 January 2021

Finding the right fold

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7 January 2021

Folding intermediates are involved in genetic diseases?

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7 January 2021

NMR structure of the mouse prion protein domain PrP(121-231)

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7 January 2021

Cloning the human lysozyme cDNA: inverted Alu repeat in the mRNA and in situ hybridization for macrophages and Paneth cells

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7 January 2021

Serum and urinary lysozyme (muramidase) in monocytic and monomyelocytic leukemia

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7 January 2021

p-nitrophenyl penta-N-acetyl-beta-chitopentaoside as a novel synthetic substrate for the colorimetric assay of lysozyme

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7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

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7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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7 January 2021

Unpaired cysteine-54 interferes with the ability of an engineered disulfide to stabilize T4 lysozyme

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7 January 2021

Primary structure effects on peptide group hydrogen exchange

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7 January 2021

The structure, stability, and folding process of amyloidogenic mutant human lysozyme

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7 January 2021

Identifiers

DOI

10.1038/385787A0

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

2058794

1030864357

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2058794

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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