Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). (Q37380777)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24014644%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11) (English)

1 reference

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20 February 2020

2

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20 February 2020

Edward L. LeCluyse

6

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20 February 2020

Christel A. S. Bergström

3

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20 February 2020

Agneta Norén

5

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20 February 2020

author name string

Jenny M Pedersen

1

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20 February 2020

Janet Hoogstraate

4

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20 February 2020

Per Artursson

7

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20 February 2020

publication date

6 September 2013

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20 February 2020

published in

Toxicological Sciences

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20 February 2020

volume

136

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20 February 2020

page(s)

328-343

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20 February 2020

issue

2

1 reference

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Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification

20 February 2020

cites work

1 reference

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6 September 2017

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6 September 2017

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6 September 2017

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3'-Azido-3'-deoxythymidine (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: a possible mechanism of AZT hepatotoxicity

6 September 2017

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Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin

6 September 2017

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6 September 2017

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6 September 2017

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Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11

6 September 2017

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Drug-induced hepatotoxicity.

6 September 2017

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Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues.

6 September 2017

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Timing of new black box warnings and withdrawals for prescription medications

6 September 2017

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Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver

6 September 2017

1 reference

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Immunological perspectives on chronic hepatitis: virus infection, autoimmunity and xenobiotics

6 September 2017

1 reference

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Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis

6 September 2017

1 reference

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The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver

6 September 2017

1 reference

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Clinical and biochemical findings in progressive familial intrahepatic cholestasis

6 September 2017

1 reference

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Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858191

Effect of membrane cholesterol on BSEP/Bsep activity: species specificity studies for substrates and inhibitors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858191

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858191

Involvement of multiple efflux transporters in hepatic disposition of fexofenadine

14 September 2017

1 reference

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A global drug inhibition pattern for the human ATP-binding cassette transporter breast cancer resistance protein (ABCG2).

14 September 2017

1 reference

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Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines.

14 September 2017

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Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration.

14 September 2017

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A comprehensive evaluation of metabolic activity and intrinsic clearance in suspensions and monolayer cultures of cryopreserved primary human hepatocytes

26 June 2018

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In vivo biliary clearance should be predicted by intrinsic biliary clearance in sandwich-cultured hepatocytes.

2 September 2018

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Cloning of the dog bile salt export pump (BSEP; ABCB11) and functional comparison with the human and rat proteins

2 September 2018

1 reference

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Role of enzymatic N-hydroxylation and reduction in flutamide metabolite-induced liver toxicity

2 September 2018

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Cellular imaging predictions of clinical drug-induced liver injury

2 September 2018

1 reference

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Severe bile salt export pump deficiency: 82 different ABCB11 mutations in 109 families.

2 September 2018

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Suspected drug-induced liver fatalities reported to the WHO database

2 September 2018

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The effect of valproic acid on hepatic and plasma levels of 15-F2t-isoprostane in rats

2 September 2018

1 reference

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FDA-approved drug labeling for the study of drug-induced liver injury

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858191

A new approach on valproic acid induced hepatotoxicity: involvement of lysosomal membrane leakiness and cellular proteolysis

3 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24014644

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Overtaking the DILI Model-T

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24014644

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/TOXSCI/KFT197

1 reference

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20 February 2020

1 reference

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20 February 2020

1 reference

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