The effect of valproic acid on hepatic and plasma levels of 15-F2t-isoprostane in rats (Q44448216)

3 December 2017

The effect of valproic acid on hepatic and plasma levels of 15-F2t-isoprostane in rats (English)

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3 December 2017

Vincent Tong

1

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3 December 2017

Thomas K H Chang

series ordinal

2

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3 December 2017

Jie Chen

series ordinal

3

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3 December 2017

Frank S Abbott

series ordinal

4

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3 December 2017

1 June 2003

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Free Radical Biology and Medicine

3 December 2017

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3 December 2017

34

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3 December 2017

11

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3 December 2017

1435-1446

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Valproate-induced hepatic injury: analyses of 23 fatal cases

3 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Valproic acid hepatic fatalities: a retrospective review

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Valproic acid hepatic fatalities. II. US experience since 1984.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Valproic acid hepatic fatalities. III. U.S. experience since 1986.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Protection against sodium valproate injury in isolated hepatocytes by alpha-tocopherol and N,N'-diphenyl-p-phenylenediamine

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Selenium, zinc, and copper changes with valproic acid: possible relation to drug side effects.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Early changes in hepatic redox homeostasis following treatment with a single dose of valproic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Cytotoxicity of unsaturated metabolites of valproic acid and protection by vitamins C and E in glutathione-depleted rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Biochemical basis of sodium valproate hepatotoxicity and renal tubular disorder: time dependence of peroxidative injury

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Altered antioxidant enzyme activities in children with a serious adverse experience related to valproic acid therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Assessing the mechanism of metabolism-dependent valproic acid-induced in vitro cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Effect of acute and chronic administration of sodium valproate on lipid peroxidation and antioxidant system in rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Evidence for a trigger function of valproic acid in xenobiotic-induced hepatotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Aspects of the metabolism of valproic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

In vitro effects of valproate and valproate metabolites on mitochondrial oxidations. Relevance of CoA sequestration to the observed inhibitions.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Reye-like syndrome associated with valproic acid therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Valproate-induced hepatic steatogenesis in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

The hepatotoxicity of valproic acid and its metabolites in rats. I. Toxicologic, biochemical and histopathologic studies

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Effects of polytherapy with phenytoin, carbamazepine, and stiripentol on formation of 4-ene-valproate, a hepatotoxic metabolite of valproic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

A rapid in vitro assay for evaluation of metabolism-dependent cytotoxicity of antiepileptic drugs on isolated human lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

LC/MS analysis of hydroxylation products of salicylate as an indicator of in vivo oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Isoprostanes as a biomarker of lipid peroxidation in humans: physiology, pharmacology and clinical implications

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Analysis of F2-isoprostanes as indicators of non-enzymatic lipid peroxidation in vivo by gas chromatography-mass spectrometry: development of a solid-phase extraction procedure

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Metabolic profiling of valproic acid by cDNA-expressed human cytochrome P450 enzymes using negative-ion chemical ionization gas chromatography-mass spectrometry.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Autocatalytic alkylation of the cytochrome P-450 prosthetic haem group by 1-aminobenzotriazole. Isolation of an NN-bridged benzyne-protoporphyrin IX adduct.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

1-Aminobenzotriazole-induced destruction of hepatic and renal cytochromes P450 in male Sprague-Dawley rats

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Complexation of cytochrome P-450 isozymes in hepatic microsomes from SKF 525-A-induced rats

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Fluorinated analogues as mechanistic probes in valproic acid hepatotoxicity: hepatic microvesicular steatosis and glutathione status

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Metabolism of valproate to hepatotoxic intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Metabolic activation of unsaturated derivatives of valproic acid. Identification of novel glutathione adducts formed through coenzyme A-dependent and -independent processes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Bioactivation of a toxic metabolite of valproic acid, (E)-2-propyl-2,4-pentadienoic acid, via glucuronidation. LC/MS/MS characterization of the GSH-glucuronide diconjugates

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Measurement of urinary F(2)-isoprostanes as markers of in vivo lipid peroxidation-A comparison of enzyme immunoassay with gas chromatography/mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

An improved method for the measurement of urinary and plasma F2-isoprostanes using gas chromatography-mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Determination of isoprostaglandin F2alpha type III in human urine by gas chromatography-electronic impact mass spectrometry. Comparison with enzyme immunoassay.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Changes in the antioxidant system in epileptic children receiving antiepileptic drugs: two-year prospective studies.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Oxidative injury induced cyclooxygenase activation in experimental hepatotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Vitamin E reduces lipid peroxidation in experimental hepatotoxicity in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Contribution of hepatic cytochrome P450 systems to the generation of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Association of cytochrome P450 induction with oxidative stress in vivo as evidenced by 3-hydroxylation of salicylate

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

The peroxisome proliferator response element of the gene encoding the peroxisomal beta-oxidation enzyme enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase is a target for constitutive androstane receptor beta/9-cis-retinoic acid receptor-mediated t

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900151-5

7 January 2021

10.1016/S0891-5849(03)00151-5

Identifiers

DOI

1 reference

3 December 2017

1 reference