3'-Azido-3'-deoxythymidine (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: a possible mechanism of AZT hepatotoxicity (Q34652444)

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English	3'-Azido-3'-deoxythymidine (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: a possible mechanism of AZT hepatotoxicity	scientific article

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

3'-Azido-3'-deoxythymidine (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: a possible mechanism of AZT hepatotoxicity (English)

1 reference

Europe PubMed Central

3 August 2017

phosphorylation

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based on heuristic

inferred from title

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based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Matthew D Lynx

1

1 reference

Europe PubMed Central

3 August 2017

Alice T Bentley

2

1 reference

Europe PubMed Central

3 August 2017

Edward E McKee

3

1 reference

Europe PubMed Central

3 August 2017

language of work or name

0 references

publication date

10 February 2006

1 reference

Europe PubMed Central

3 August 2017

Biochemical Pharmacology

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Europe PubMed Central

3 August 2017

71

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Europe PubMed Central

3 August 2017

1342-1348

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Europe PubMed Central

3 August 2017

9

1 reference

Europe PubMed Central

3 August 2017

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Adverse effects of antiretroviral therapy in HIV-1 infected children

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DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity.

1 reference

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Phosphorylation of thymidine and AZT in heart mitochondria: elucidation of a novel mechanism of AZT cardiotoxicity

1 reference

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Mitochondrial deoxyribonucleoside triphosphate pools in thymidine kinase 2 deficiency

1 reference

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mtDNA depletion myopathy: elucidation of the tissue specificity in the mitochondrial thymidine kinase (TK2) deficiency

1 reference

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Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy

1 reference

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1 reference

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Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase.

1 reference

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Human thymidine kinase 2: molecular cloning and characterisation of the enzyme activity with antiviral and cytostatic nucleoside substrates

1 reference

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1 reference

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Physiological concentrations of purines and pyrimidines

1 reference

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Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis

1 reference

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Metabolic abnormalities in skeletal muscle of patients receiving zidovudine therapy observed by 31P in vivo magnetic resonance spectroscopy

1 reference

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Mitochondrial toxicity of antiviral drugs

1 reference

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Regulation of thymidine kinase activity in the cell cycle by a labile protein

1 reference

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1 reference

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1 reference

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Zidovudine induces molecular, biochemical, and ultrastructural changes in rat skeletal muscle mitochondria

1 reference

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Site specific alterations of adipose tissue mitochondria in 3'-azido-3'-deoxythymidine (AZT)-treated rats: an early stage in lipodystrophy?

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Zidovudine phosphorylation and mitochondrial toxicity in vitro

1 reference

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Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma

1 reference

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Zidovudine-induced mitochondrial disorder with massive liver steatosis, myopathy, lactic acidosis, and mitochondrial DNA depletion.

1 reference

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1 reference

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Early features of zidovudine-associated myopathy: histopathological findings and clinical correlations

1 reference

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Massive hepatic steatosis and lactic acidosis in a patient with AIDS who was receiving zidovudine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16472780

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Hepatic Morphological alterations induced by zidovudine (ZDV) in an experimental model

1 reference

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1 reference

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inferred from PubMed ID database lookup

The bottleneck in AZT activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16472780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BCP.2006.01.003

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

ResearchGate publication ID

0 references

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