Role of cytokines in thymus- versus peripherally derived-regulatory T cell differentiation and function (Q36938226)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23801992%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Role of cytokines in thymus- versus peripherally derived-regulatory T cell differentiation and function (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23801992%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

5

1 reference

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3 March 2020

Eliane Piaggio

6

1 reference

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3 March 2020

author name string

Jérémie David Goldstein

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23801992%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Louis Pérol

2

1 reference

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3 March 2020

Bruno Zaragoza

3

1 reference

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3 March 2020

Audrey Baeyens

4

1 reference

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3 March 2020

publication date

19 June 2013

1 reference

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3 March 2020

published in

Frontiers in Immunology

1 reference

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3 March 2020

volume

4

1 reference

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3 March 2020

page(s)

155

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23801992%20AND%20SRC:MED&resulttype=core&format=json

Development and maintenance of regulatory T cells

3 March 2020

cites work

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An essential role of the transcription factor GATA-3 for the function of regulatory T cells

29 September 2017

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Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+CD25+Foxp3+ regulatory T cells

29 September 2017

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A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity

29 September 2017

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Continuous activation of the CD122/STAT-5 signaling pathway during selection of antigen-specific regulatory T cells in the murine thymus

29 September 2017

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IL-2 controls the stability of Foxp3 expression in TGF-beta-induced Foxp3+ T cells in vivo

29 September 2017

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TNF optimally activatives regulatory T cells by inducing TNF receptor superfamily members TNFR2, 4-1BB and OX40

29 September 2017

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29 September 2017

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Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

29 September 2017

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The Ets-1 transcription factor controls the development and function of natural regulatory T cells.

29 September 2017

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IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

29 September 2017

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PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

29 September 2017

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29 September 2017

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Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

29 September 2017

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Suppression of murine allergic airway disease by IL-2:anti-IL-2 monoclonal antibody-induced regulatory T cells

29 September 2017

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CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells

29 September 2017

1 reference

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Plasmacytoid dendritic cells mediate oral tolerance

29 September 2017

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How regulatory T cells work

29 September 2017

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Unravelling the association of partial T-cell immunodeficiency and immune dysregulation

29 September 2017

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T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.

29 September 2017

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Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction

29 September 2017

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The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells

29 September 2017

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STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells.

29 September 2017

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Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.

29 September 2017

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A two-step process for thymic regulatory T cell development.

29 September 2017

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TNF-alpha antagonism generates a population of antigen-specific CD4+CD25+ T cells that inhibit protective immunity in murine histoplasmosis

29 September 2017

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Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer

29 September 2017

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Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells

29 September 2017

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Pathobiology of transforming growth factor beta in cancer, fibrosis and immunologic disease, and therapeutic considerations

29 September 2017

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Dendritic cells are specialized accessory cells along with TGF- for the differentiation of Foxp3+ CD4+ regulatory T cells from peripheral Foxp3 precursors

29 September 2017

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Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

29 September 2017

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A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

29 September 2017

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Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

29 September 2017

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Cutting Edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells

29 September 2017

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Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

29 September 2017

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Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta

29 September 2017

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Epigenetic control of the foxp3 locus in regulatory T cells

29 September 2017

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Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity

29 September 2017

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Nonredundant roles for Stat5a/b in directly regulating Foxp3

29 September 2017

1 reference

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Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor

29 September 2017

1 reference

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Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms

29 September 2017

1 reference

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FOXP3 controls regulatory T cell function through cooperation with NFAT

29 September 2017

1 reference

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Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts.

29 September 2017

1 reference

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TNF downmodulates the function of human CD4+CD25hi T-regulatory cells

29 September 2017

1 reference

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An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires

29 September 2017

1 reference

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Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen

29 September 2017

1 reference

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A function for interleukin 2 in Foxp3-expressing regulatory T cells

29 September 2017

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Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling

29 September 2017

1 reference

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Developmental regulation of Foxp3 expression during ontogeny.

29 September 2017

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Oral tolerance in the absence of naturally occurring Tregs

29 September 2017

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TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

29 September 2017

1 reference

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Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms

29 September 2017

1 reference

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T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells

29 September 2017

1 reference

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Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

29 September 2017

1 reference

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A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

29 September 2017

1 reference

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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

29 September 2017

1 reference

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Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

29 September 2017

1 reference

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CD4+ CD25+ T cells responding to serologically defined autoantigens suppress antitumor immune responses

29 September 2017

1 reference

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

29 September 2017

1 reference

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Control of regulatory T cell development by the transcription factor Foxp3

29 September 2017

1 reference

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Interleukin 2 signaling is required for CD4(+) regulatory T cell function

29 September 2017

1 reference

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Tumor necrosis factor-alpha regulation of CD4+CD25+ T cell levels in NOD mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

TNF-R1 signaling: a beautiful pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Pathogenic T cells have a paradoxical protective effect in murine autoimmune diabetes by boosting Tregs.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Stability of the regulatory T cell lineage in vivo.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Protein kinase C-theta mediates negative feedback on regulatory T cell function

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

TNF-α impairs differentiation and function of TGF-β-induced Treg cells in autoimmune diseases through Akt and Smad3 signaling pathway

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Cytokine therapy with interleukin-2/anti-interleukin-2 monoclonal antibody complexes expands CD4+CD25+Foxp3+ regulatory T cells and attenuates development and progression of atherosclerosis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Interplay between TNF and regulatory T cells in a TNF-driven murine model of arthritis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Critical role for TNF in the induction of human antigen-specific regulatory T cells by tolerogenic dendritic cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

TNF activates a NF-kappaB-regulated cellular program in human CD45RA- regulatory T cells that modulates their suppressive function.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

DNA methylation controls Foxp3 gene expression

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Regulatory T cell development in the absence of functional Foxp3.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

In vitro suppression of CD8+ T cell function by Friend virus-induced regulatory T cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

Cytokines and murine autoimmune encephalomyelitis: inhibition or enhancement of disease with antibodies to select cytokines, or by delivery of exogenous cytokines using a recombinant vaccinia virus system

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685818

T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development

4 September 2018

1 reference

12 December 2020

Requirement for receptor-bound urokinase in plasmin-dependent cellular conversion of latent TGF-beta to TGF-beta

1 reference

12 December 2020

Inducing and expanding regulatory T cell populations by foreign antigen

1 reference

12 December 2020

Cutting Edge: TNFR-Shedding by CD4+CD25+ Regulatory T Cells Inhibits the Induction of Inflammatory Mediators

1 reference

12 December 2020

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

1 reference

12 December 2020

Foxp3-dependent programme of regulatory T-cell differentiation

1 reference

12 December 2020

IL-2Rbeta links IL-2R signaling with Foxp3 expression

1 reference

12 December 2020

Natural but not inducible regulatory T cells require TNF-alpha signaling for in vivo function

1 reference

12 December 2020

Tumor necrosis factor (TNF) receptor type 2 mediates thymocyte proliferation independently of TNF receptor type 1

1 reference

12 December 2020

Urokinase receptor. An activation antigen in human T lymphocytes

1 reference

12 December 2020

Impact of protective IL-2 allelic variants on CD4+ Foxp3+ regulatory T cell function in situ and resistance to autoimmune diabetes in NOD mice

1 reference

12 December 2020

Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

1 reference

12 December 2020

IL-2 production by dendritic cells promotes Foxp3(+) regulatory T-cell expansion in autoimmune-resistant NOD congenic mice

1 reference

12 December 2020

Functional and molecular characteristics of T-cell growth factor

1 reference

12 December 2020

Tracing the action of IL-2 in tolerance to islet-specific antigen

1 reference

12 December 2020

Upregulation of Foxp3 expression in mouse and human Treg is IL-2/STAT5 dependent: implications for the NOD STAT5B mutation in diabetes pathogenesis

1 reference

12 December 2020

A critical function for TGF-beta signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells

1 reference

12 December 2020

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

1 reference

12 December 2020

Foxp3 Transcription-Factor-Dependent and -Independent Regulation of the Regulatory T Cell Transcriptional Signature

1 reference

12 December 2020

Indexation as a novel mechanism of lymphocyte homeostasis: the number of CD4+CD25+ regulatory T cells is indexed to the number of IL-2-producing cells

1 reference

12 December 2020

Identifiers

DOI

10.3389/FIMMU.2013.00155

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23801992%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23801992%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23801992%20AND%20SRC:MED&resulttype=core&format=json