Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells (Q24676386)

Transforming growth factor, beta 1

GOA release 2020-03-11

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GOA release 2020-03-11

5

Richard A Flavell

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author name string

Daniel H Kaplan

1

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Ming O Li

2

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Matthew C Jenison

3

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Warren D Shlomchik

4

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Mark J Shlomchik

Journal of Experimental Medicine

6

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language of work or name

English

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publication date

29 October 2007

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published in

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volume

204

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issue

11

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page(s)

2545-52

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cites work

Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules

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T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation

7 April 2017

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Transforming growth factor-beta regulation of immune responses

7 April 2017

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Langerhans cells arise from monocytes in vivo

7 April 2017

1 reference

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Identification and expression of mouse Langerin (CD207) in dendritic cells

7 April 2017

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Codon-improved Cre recombinase (iCre) expression in the mouse

7 April 2017

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Epidermal langerhans cell-deficient mice develop enhanced contact hypersensitivity

7 April 2017

1 reference

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Mouse lymphoid tissue contains distinct subsets of langerin/CD207 dendritic cells, only one of which represents epidermal-derived Langerhans cells

28 September 2017

1 reference

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Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease

28 September 2017

1 reference

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Langerhans cells - dendritic cells of the epidermis.

28 September 2017

1 reference

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TGF-beta signaling-deficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro

28 September 2017

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Transcriptional profiling identifies Id2 function in dendritic cell development

28 September 2017

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Langerhans cells renew in the skin throughout life under steady-state conditions

28 September 2017

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A role for TGFbeta1 in langerhans cell biology. Further characterization of the epidermal Langerhans cell defect in TGFbeta1 null mice

28 September 2017

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A role for endogenous transforming growth factor beta 1 in Langerhans cell biology: the skin of transforming growth factor beta 1 null mice is devoid of epidermal Langerhans cells

28 September 2017

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Expression of transforming growth factor-beta 1 in specific cells and tissues of adult and neonatal mice

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Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization

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Langerhans cells are strongly reduced in the skin of transgenic mice overexpressing follistatin in the epidermis

28 September 2017

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Transforming growth factor beta1, in the presence of granulocyte/macrophage colony-stimulating factor and interleukin 4, induces differentiation of human peripheral blood monocytes into dendritic Langerhans cells

30 May 2018

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Skin antigens in the steady state are trafficked to regional lymph nodes by transforming growth factor-beta1-dependent cells.

30 May 2018

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Ontogeny of Langerin/CD207 expression in the epidermis of mice.

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Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells.

21 January 2018

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Conditional inactivation of the TGF-beta type II receptor using Cre:Lox

21 January 2018

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A model system using tape stripping for characterization of Langerhans cell-precursors in vivo.

21 January 2018

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Appearance of Langerhans cells in the epidermis of Tgfb1(-/-) SCID mice: paracrine and autocrine effects of transforming growth factor-beta 1 and -beta 2(1)

21 January 2018

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12 December 2020

TGF-beta 1 promotes in vitro development of dendritic cells from CD34+ hemopoietic progenitors

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12 December 2020

Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain

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12 December 2020

A rapid method for targeted modification and screening of recombinant bacterial artificial chromosome

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12 December 2020

Dermal-resident CD14+ cells differentiate into Langerhans cells

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12 December 2020