TNF-alpha: an activator of CD4+FoxP3+TNFR2+ regulatory T cells. (Q37696079)

22 August 2017

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title

TNF-alpha: an activator of CD4+FoxP3+TNFR2+ regulatory T cells (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314650&resulttype=core&format=json

13 May 2020

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314650&resulttype=core&format=json

13 May 2020

author name string

Joost J Oppenheim

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314650&resulttype=core&format=json

13 May 2020

publication date

18 February 2010

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Current directions in autoimmunity

22 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314650&resulttype=core&format=json

13 May 2020

volume

11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314650&resulttype=core&format=json

13 May 2020

page(s)

119-134

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314650&resulttype=core&format=json

Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific

13 May 2020

cites work

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12 December 2020

Inhibition of IL-12 production in human monocyte-derived macrophages by TNF

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12 December 2020

CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells

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12 December 2020

Accelerated autoimmunity and lupus nephritis in NZB mice with an engineered heterozygous deficiency in tumor necrosis factor

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12 December 2020

TNF regulates thymocyte production by apoptosis and proliferation of the triple negative (CD3-CD4-CD8-) subset

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12 December 2020

Divergent roles for p55 and p75 tumor necrosis factor receptors in the pathogenesis of MOG(35-55)-induced experimental autoimmune encephalomyelitis.

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12 December 2020

Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: implications for pathogenesis and therapy of autoimmune demyelination

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12 December 2020

Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells

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12 December 2020

Transforming growth factor beta enhances the expression of CD154 (CD40L) and production of tumor necrosis factor alpha by human T lymphocytes

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12 December 2020

TNF type 2 receptor (p75) lowers the threshold of T cell activation

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12 December 2020

The role of TNF/TNFR in organ-specific and systemic autoimmunity: implications for the design of optimized 'anti-TNF' therapies

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12 December 2020

The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells

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12 December 2020

Development of anti-TNF therapy for rheumatoid arthritis

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12 December 2020

Native and Genetically Inactivated Pertussis Toxins Induce Human Dendritic Cell Maturation and Synergize with Lipopolysaccharide in Promoting T Helper Type 1 Responses

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12 December 2020

Phenotype, localization, and mechanism of suppression of CD4(+)CD25(+) human thymocytes

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12 December 2020

Role of TNF/TNFR in autoimmunity: specific TNF receptor blockade may be advantageous to anti-TNF treatments

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12 December 2020

Tumor necrosis factor-alpha regulation of CD4+CD25+ T cell levels in NOD mice

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12 December 2020

Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells

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12 December 2020

Bordetella pertussis toxin induces the release of inflammatory cytokines and dendritic cell activation in whole blood: impaired responses in human newborns

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12 December 2020

Inflammation and cancer

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12 December 2020

Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis

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12 December 2020

Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes

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12 December 2020

Human CD4+ CD25+ regulatory T cells suppress NKT cell functions

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12 December 2020

Signalling pathways of the TNF superfamily: a double-edged sword

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12 December 2020

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

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12 December 2020

CD4+CD25bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis.

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12 December 2020

CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease

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12 December 2020

Function and regulation of tumor necrosis factor receptor type 2.

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12 December 2020

Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy

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12 December 2020

CD4+CD25+ T regulatory cells inhibit cytotoxic activity of T CD8+ and NK lymphocytes in the direct cell-to-cell interaction

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12 December 2020

Tolerance, not immunity, crucially depends on IL-2.

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12 December 2020

Critical role of TNF receptor type-2 (p75) as a costimulator for IL-2 induction and T cell survival: a functional link to CD28.

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12 December 2020

CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid

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12 December 2020

CD25+CD4+ regulatory T cells generated by exposure to a model protein antigen prevent allograft rejection: antigen-specific reactivation in vivo is critical for bystander regulation

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12 December 2020

Natural regulatory T cells in infectious disease

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12 December 2020

Opposing effects of tumor necrosis factor receptor 1 and 2 in sepsis due to cecal ligation and puncture

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12 December 2020

CD4+ CD25+ T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis

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12 December 2020

TNF pathophysiology in murine models of chronic inflammation and autoimmunity.

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12 December 2020

Regulatory T cells in rheumatoid arthritis

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12 December 2020

Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia

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12 December 2020

Increased spontaneous apoptosis of CD4+CD25+ T cells in patients with active rheumatoid arthritis is reduced by infliximab.

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12 December 2020

Paradoxical Anti-Inflammatory Actions of TNF- : Inhibition of IL-12 and IL-23 via TNF Receptor 1 in Macrophages and Dendritic Cells

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12 December 2020

What does tumour necrosis factor excess do to the immune system long term?

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12 December 2020

TNF receptor type 2 (p75) functions as a costimulator for antigen-driven T cell responses in vivo.

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12 December 2020

Pertussis toxin as an adjuvant suppresses the number and function of CD4+CD25+ T regulatory cells

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12 December 2020

An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires

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12 December 2020

TNF downmodulates the function of human CD4+CD25hi T-regulatory cells

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12 December 2020

Regulatory T cells, tumour immunity and immunotherapy

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12 December 2020

Glucocorticoid amplifies IL-2-dependent expansion of functional FoxP3(+)CD4(+)CD25(+) T regulatory cells in vivo and enhances their capacity to suppress EAE

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12 December 2020

Pertussis toxin reduces the number of splenic Foxp3+ regulatory T cells.

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12 December 2020

Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta

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12 December 2020

Natural regulatory T cells: mechanisms of suppression

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12 December 2020

Where FoxP3-dependent regulatory T cells impinge on the development of inflammatory arthritis

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12 December 2020

FOXP3 modifies the phenotypic and functional properties of regulatory T cells

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12 December 2020

Foxp3 in control of the regulatory T cell lineage

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12 December 2020

Pertussis toxin by inducing IL-6 promotes the generation of IL-17-producing CD4 cells

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12 December 2020

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

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12 December 2020

Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells.

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12 December 2020

Myocarditis following adeno-associated viral gene expression of human soluble TNF receptor (TNFRII-Fc) in baboon hearts.

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12 December 2020

Regulatory T cell populations in sepsis and trauma.

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12 December 2020

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked: forkhead box protein 3 mutations and lack of regulatory T cells

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12 December 2020

AAV vectors and cardiovascular disease: targeting TNF receptor in the heart: clue to way forward with AAV?

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12 December 2020

CD4+CD25+FoxP3+ regulatory T cells in autoimmune diseases

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12 December 2020

The inhibitory cytokine IL-35 contributes to regulatory T-cell function

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12 December 2020

Accumulation of FoxP3-expressing CD4+CD25+ T cells with distinct chemokine receptors in synovial fluid of patients with active rheumatoid arthritis

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12 December 2020

TNF-alpha antagonism generates a population of antigen-specific CD4+CD25+ T cells that inhibit protective immunity in murine histoplasmosis

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12 December 2020

Cutting Edge: TNFR-Shedding by CD4+CD25+ Regulatory T Cells Inhibits the Induction of Inflammatory Mediators

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12 December 2020

Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4+CD25+FoxP3+ T regulatory cells: applicability to tumor-infiltrating T regulatory cells.

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12 December 2020

Physiological functions of tumor necrosis factor and the consequences of its pathologic overexpression or blockade: mouse models

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12 December 2020

Regulatory T cells and immune tolerance

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12 December 2020

In vitro suppression of xenoimmune-mediated macrophage activation by human CD4+CD25+ regulatory T cells

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12 December 2020

CTLA-4 control over Foxp3+ regulatory T cell function

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12 December 2020

Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells

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12 December 2020

Human CD4+ CD25+ Foxp3+ regulatory T cells do not constitutively express IL-35.

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12 December 2020

Suppression of murine allergic airway disease by IL-2:anti-IL-2 monoclonal antibody-induced regulatory T cells

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12 December 2020

Increased number and function of FoxP3 regulatory T cells during experimental arthritis

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12 December 2020

Inducible reprogramming of human T cells into Treg cells by a conditionally active form of FOXP3

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12 December 2020

Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cells: a role for cycling TNFR2-expressing effector-suppressor T cells in limiting effective chemotherapy

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12 December 2020

CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance

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12 December 2020

Cytokine/Antibody complexes: an emerging class of immunostimulants

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12 December 2020

Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1.

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12 December 2020

Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis

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12 December 2020

Cell interactions in the induction of tolerance: the role of thymic lymphocytes

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12 December 2020

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

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12 December 2020

Stimulation of human T-cell proliferation by specific activation of the 75-kDa tumor necrosis factor receptor

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12 December 2020

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

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12 December 2020

Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells

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12 December 2020

Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling

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12 December 2020

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

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12 December 2020

Regulation of autoimmunity by proinflammatory cytokines

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12 December 2020

Identifiers

DOI

10.1159/000289201

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314650&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314650&resulttype=core&format=json

13 May 2020

1 reference