Epigenetic silencing of the proapoptotic gene BIM in anaplastic large cell lymphoma through an MeCP2/SIN3a deacetylating complex. (Q36801093)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23633923%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Epigenetic silencing of the proapoptotic gene BIM in anaplastic large cell lymphoma through an MeCP2/SIN3a deacetylating complex (English)

1 reference

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29 February 2020

0 references

2

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29 February 2020

Chiara Ambrogio

5

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29 February 2020

Roberto Chiarle

6

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29 February 2020

Richard B Lock

9

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29 February 2020

Paola Collini

10

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Carlo Gambacorti-Passerini

29 February 2020

12

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29 February 2020

author name string

Rocco Piazza

1

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29 February 2020

Angela Mogavero

3

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29 February 2020

Federica Andreoni

4

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29 February 2020

Luca Mologni

7

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29 February 2020

Petra S Bachmann

8

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29 February 2020

Giuseppe Pelosi

11

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29 February 2020

language of work or name

1 reference

1 May 2013

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29 February 2020

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29 February 2020

volume

15

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29 February 2020

page(s)

511-522

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29 February 2020

issue

5

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Role of ERK-BIM and STAT3-survivin signaling pathways in ALK inhibitor-induced apoptosis in EML4-ALK-positive lung cancer

29 February 2020

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.

29 September 2017

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Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM.

29 September 2017

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Bim is a suppressor of Myc-induced mouse B cell leukemia

29 September 2017

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NPM-ALK fusion kinase of anaplastic large-cell lymphoma regulates survival and proliferative signaling through modulation of FOXO3a

29 September 2017

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Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim.

29 September 2017

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CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK)

29 September 2017

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Profiling aberrant DNA methylation in hematologic neoplasms: a view from the tip of the iceberg

29 September 2017

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Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

29 September 2017

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N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso

29 September 2017

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Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

29 September 2017

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The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties

29 September 2017

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Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation

29 September 2017

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Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.

29 September 2017

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The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

29 September 2017

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29 September 2017

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Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim

29 September 2017

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The Ski protein family is required for MeCP2-mediated transcriptional repression

29 September 2017

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Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors

29 September 2017

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Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

29 September 2017

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Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3

29 September 2017

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DNA hypermethylation in tumorigenesis: epigenetics joins genetics

29 September 2017

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

29 September 2017

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Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

29 September 2017

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Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

29 September 2017

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Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

29 September 2017

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Effects of DNA methylation on DNA-binding proteins and gene expression.

29 September 2017

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The 5-methylcytosine content of DNA from human tumors

29 September 2017

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Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter

29 September 2017

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NPM-ALK oncogenic tyrosine kinase controls T-cell identity by transcriptional regulation and epigenetic silencing in lymphoma cells

29 September 2017

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MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.

27 June 2018

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DNA hypermethylation promotes the low expression of pro-apoptotic BCL2L11 associated with BCR-ABL1 fusion gene of chronic myeloid leukaemia.

27 June 2018

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Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition.

5 September 2018

1 reference

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Epigenetic down-regulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukaemia.

5 September 2018

1 reference

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Cell type-specific methylation of an intronic CpG island controls expression of the MCJ gene.

5 September 2018

1 reference

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JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

5 September 2018

1 reference

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Hypermethylation of the gene promoter and enhancer region can regulate Fas expression and sensitivity in colon carcinoma

5 September 2018

1 reference

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5 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23633923

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential methylation pattern of the X-linked lymphoproliferative (XLP) disease gene SH2D1A correlates with the cell lineage-specific transcription

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23633923

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1593/NEO.121784

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23633923%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23633923%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23633923%20AND%20SRC:MED&resulttype=core&format=json