DNA hypermethylation in tumorigenesis: epigenetics joins genetics (Q33870798)

29 July 2017

title

DNA hypermethylation in tumorigenesis: epigenetics joins genetics (English)

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29 July 2017

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Baylin SB

1

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29 July 2017

Herman JG

series ordinal

2

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29 July 2017

publication date

1 April 2000

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29 July 2017

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29 July 2017

volume

16

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29 July 2017

issue

4

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29 July 2017

page(s)

168-174

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publication type of scholarly work

29 July 2017

review article

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ONCOGENESIS: Landscaping the Cancer Terrain

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Imprinting and the Initiation of Gene Silencing in the Germ Line

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Cancer epigenetics comes of age

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Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

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A cell cycle regulator potentially involved in genesis of many tumor types

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Clues to the pathogenesis of familial colorectal cancer

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Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

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Mutations of the BRCA1 gene in human cancer

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Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas

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MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas

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Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome

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Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon

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Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis

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Aberrant methylation of p16 INK4a is an early event in lung cancer and a potential biomarker for early diagnosis

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Progressive region-specific de novo methylation of the p16 CpG island in primary human mammary epithelial cell strains during escape from M(0) growth arrest

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In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis

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Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

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hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis

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Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

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Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

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MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

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Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

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Transcriptional coregulators in development.

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Histone acetylation and transcriptional regulatory mechanisms

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Suppression of intestinal neoplasia by DNA hypomethylation

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Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis

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De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase

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Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation

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DNA methylation represses transcription in vivo

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7 January 2021

Chromatin remodeling: a marriage between two families?

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Maintenance of genomic methylation requires a SWI2/SNF2-like protein

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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

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Rapid analysis of DNA methylation using new restriction enzyme sites created by bisulfite modification

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Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation

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Role of Estrogen Receptor Gene Demethylation and DNA Methyltransferase·DNA Adduct Formation in 5-Aza-2′deoxycytidine-induced Cytotoxicity In Human Breast Cancer Cells

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Identifiers

DOI

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29 July 2017

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