Stress and mTORture signaling (Q36623669)

15 August 2017

1 reference

title

Stress and mTORture signaling (English)

1 reference

15 August 2017

Reiling JH

1

1 reference

15 August 2017

Sabatini DM

series ordinal

2

1 reference

15 August 2017

language of work or name

English

0 references

publication date

1 October 2006

1 reference

15 August 2017

1 reference

15 August 2017

25

1 reference

15 August 2017

48

1 reference

15 August 2017

6373-6383

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209889

15 August 2017

0 references

cites work

Dietary restriction in long-lived dwarf flies.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

How are the sizes of cells, organs, and bodies controlled?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

Genetics: influence of TOR kinase on lifespan in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Hydrogen peroxide activates p70(S6k) signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

ROS, stress-activated kinases and stress signaling in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Signaling pathways used in trabecular matrix metalloproteinase response to mechanical stretch.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Advances in protein kinase B signalling: AKTion on multiple fronts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Activation of p70 ribosomal protein S6 kinase is an essential step in the DNA damage-dependent signaling pathway responsible for the ultraviolet B-mediated increase in interstitial collagenase (MMP-1) and stromelysin-1 (MMP-3) protein levels in huma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

TSC2 regulates VEGF through mTOR-dependent and -independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

A nutrient sensor mechanism controls Drosophila growth.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Regulation of the phosphorylation and integrity of protein synthesis initiation factor eIF4GI and the translational repressor 4E-BP1 by p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Hypertonic shock inhibits growth factor receptor signaling, induces caspase-3 activation, and causes reversible fragmentation of the mitochondrial network.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Hypothalamic mTOR signaling regulates food intake

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

The GATA transcription factors GLN3 and GAT1 link TOR to salt stress in Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Mammalian TOR: a homeostatic ATP sensor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Fluid shear stress stimulates phosphorylation of Akt in human endothelial cells: involvement in suppression of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Differential role of hydrogen peroxide in UV-induced signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Tsc2 is not a critical target of Akt during normal Drosophila development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Cap-binding protein (eukaryotic initiation factor 4E) and 4E-inactivating protein BP-1 independently regulate cap-dependent translation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

The coordinate regulation of the p53 and mTOR pathways in cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Cytoplasmic p53 polypeptide is associated with ribosomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

p53 is covalently linked to 5.8S rRNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Interactive effects of rearing temperature and oxygen on the development of Drosophila melanogaster.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Amino acid signaling through the mammalian target of rapamycin (mTOR) pathway: Role of glutamine and of cell shrinkage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Identification of FIP200 interaction with the TSC1-TSC2 complex and its role in regulation of cell size control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Genetic pathways that regulate ageing in model organisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Functional genomics identifies TOR-regulated genes that control growth and division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

An expanding role for mTOR in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Target of rapamycin-dependent activation of S6 kinase is a central step in the transduction of nutritional signals during egg development in a mosquito

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

The AMP-activated protein kinase pathway--new players upstream and downstream.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

AMP-activated protein kinase--development of the energy sensor concept.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Hypoxia--a key regulatory factor in tumour growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

The p53 pathway: positive and negative feedback loops

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Mechanical stimuli and nutrients regulate rapamycin-sensitive signaling through distinct mechanisms in skeletal muscle.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Regulation of translation factors during hindlimb unloading and denervation of skeletal muscle in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

p53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

TSC2 mediates cellular energy response to control cell growth and survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Hydrogen peroxide mediates arsenite activation of p70(s6k) and extracellular signal-regulated kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Heat shock induces two distinct S6 protein kinase activities in quiescent mammalian fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Intracellular signaling during skeletal muscle atrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Mutations in the PI3K/PTEN/TSC2 pathway contribute to mammalian target of rapamycin activity and increased translation under hypoxic conditions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

A C. elegans mutant that lives twice as long as wild type

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Autophagy as a regulated pathway of cellular degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Activation of protein kinase B (Akt/RAC-protein kinase) by cellular stress and its association with heat shock protein Hsp27.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Flow-induced DNA synthesis requires signaling to a translational control pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Redox regulation of PI 3-kinase signalling via inactivation of PTEN

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Involvement of S6 kinase and p38 mitogen activated protein kinase pathways in strain-induced alignment and proliferation of bovine aortic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Induction of autophagy and inhibition of tumorigenesis by beclin 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Heat shock activates c-Src tyrosine kinases and phosphatidylinositol 3-kinase in NIH3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Hypoxia-induced energy stress regulates mRNA translation and cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Rheb binds and regulates the mTOR kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Autophagy in metazoans: cell survival in the land of plenty

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Arabidopsis TARGET OF RAPAMYCIN interacts with RAPTOR, which regulates the activity of S6 kinase in response to osmotic stress signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Activation of the N-Ras-PI3K-Akt-mTOR pathway by hepatitis C virus: control of cell survival and viral replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Synthesis of the translational apparatus is regulated at the translational level

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Suppression of the mTOR-raptor signaling pathway by the inhibitor of heat shock protein 90 geldanamycin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Osmotic stress inhibits p70/85 S6 kinase through activation of a protein phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Drosophila Rheb GTPase is required for cell cycle progression and cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Insulin regulation of hepatic insulin-like growth factor-binding protein-1 (IGFBP-1) gene expression and mammalian target of rapamycin (mTOR) signalling is impaired by the presence of hydrogen peroxide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Reduced oxygen at high altitude limits maximum size

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Akt regulates growth by directly phosphorylating Tsc2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Hypoxia signalling in cancer and approaches to enforce tumour regression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Extension of chronological life span in yeast by decreased TOR pathway signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Regulation of mammalian translation factors by nutrients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Ribosomal protein S6 phosphorylation: from protein synthesis to cell size.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Heat shock factors and the control of the stress response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Rheb promotes cell growth as a component of the insulin/TOR signalling network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Heat-shock-induced alterations of ribosomal protein phosphorylation in plant cell cultures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Regulation of hypoxic death in C. elegans by the insulin/IGF receptor homolog DAF-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

The WD repeat: a common architecture for diverse functions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Regulation of PTEN transcription by p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Rheb is an essential regulator of S6K in controlling cell growth in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

4E-BP functions as a metabolic brake used under stress conditions but not during normal growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Starvation and oxidative stress resistance in Drosophila are mediated through the eIF4E-binding protein, d4E-BP.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Performance of a Brazilian population sample in the Boston Diagnostic Aphasia Examination: a pilot study.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Hypoxia increases the association of 4E-binding protein 1 with the initiation factor 4E in isolated rat hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Combinatorial control of the specificity of protein tyrosine phosphatases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

A heat-sensitive Arabidopsis thaliana kinase substitutes for human p70s6k function in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Free radicals, metals and antioxidants in oxidative stress-induced cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Heat shock increases the association of binding protein-1 with initiation factor 4E

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

The fission yeast TOR homolog, tor1+, is required for the response to starvation and other stresses via a conserved serine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Regulation of hunger-driven behaviors by neural ribosomal S6 kinase in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

TOR signaling in growth and metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Molecular organization of target of rapamycin complex 2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Drosophila target of rapamycin kinase functions as a multimer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Signal transduction pathways involved in phosphorylation and activation of p70S6K following exposure to UVA irradiation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209889

1 reference

Dimensions Publication ID

15 August 2017

0 references

1 reference