Redox regulation of PI 3-kinase signalling via inactivation of PTEN (Q36266420)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14532122%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

title

Redox regulation of PI 3-kinase signalling via inactivation of PTEN (English)

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19 December 2019

1

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19 December 2019

Alexander Gray

5

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19 December 2019

author name string

Deborah Bennett

2

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19 December 2019

Yvonne E Lindsay

3

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19 December 2019

Hazel Stewart

4

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19 December 2019

C Peter Downes

6

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19 December 2019

publication date

1 October 2003

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19 December 2019

language of work or name

0 references

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19 December 2019

volume

22

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19 December 2019

issue

20

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19 December 2019

page(s)

5501-5510

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Membrane-binding and activation mechanism of PTEN.

19 December 2019

cites work

1 reference

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Interfacial kinetic analysis of the tumour suppressor phosphatase, PTEN: evidence for activation by anionic phospholipids

30 September 2017

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IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

30 September 2017

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PTEN function in mammalian cell size regulation

30 September 2017

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Selenomethionine regulation of p53 by a ref1-dependent redox mechanism

30 September 2017

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Regulation of phosphatidylinositol 3-kinase activity and phosphatidylinositol 3,4,5-trisphosphate accumulation by neutrophil priming agents

30 September 2017

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Cell cycle and death control: long live Forkheads

30 September 2017

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30 September 2017

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Negative feedback regulation of the tumor suppressor PTEN by phosphoinositide-induced serine phosphorylation

30 September 2017

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The phosphoinositide 3-kinase pathway

30 September 2017

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ROS, stress-activated kinases and stress signaling in cancer

30 September 2017

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P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

30 September 2017

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Reversible inactivation of the tumor suppressor PTEN by H2O2

30 September 2017

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Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo

30 September 2017

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PTEN: The down side of PI 3-kinase signalling.

30 September 2017

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Free Radicals in the Physiological Control of Cell Function

30 September 2017

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TPIP: a novel phosphoinositide 3-phosphatase

30 September 2017

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Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

30 September 2017

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Constitutively activated Akt-1 is vital for the survival of human monocyte-differentiated macrophages. Role of Mcl-1, independent of nuclear factor (NF)-kappaB, Bad, or caspase activation.

30 September 2017

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Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions

30 September 2017

1 reference

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Protein tyrosine nitration in cytokine-activated murine macrophages. Involvement of a peroxidase/nitrite pathway rather than peroxynitrite

30 September 2017

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Synthesis and function of 3-phosphorylated inositol lipids

30 September 2017

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PTEN and myotubularin: novel phosphoinositide phosphatases

30 September 2017

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Insulin/IGF signalling and ageing: seeing the bigger picture

30 September 2017

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Phosphoinositide 3-kinase signalling pathways

30 September 2017

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Combinatorial control of the specificity of protein tyrosine phosphatases

30 September 2017

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PTEN: life as a tumor suppressor

30 September 2017

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The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation

30 September 2017

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Redox-dependent signal transduction

30 September 2017

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Phosphorylation of the PTEN tail regulates protein stability and function

30 September 2017

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Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2

30 September 2017

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Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase

30 September 2017

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The p66shc adaptor protein controls oxidative stress response and life span in mammals

30 September 2017

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Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity

30 September 2017

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PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

30 September 2017

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30 September 2017

NADPH oxidase: an update

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Activation of phosphatidylinositol 3-kinase, protein kinase B, and p70 S6 kinases in lipopolysaccharide-stimulated Raw 264.7 cells: differential effects of rapamycin, Ly294002, and wortmannin on nitric oxide production.

30 September 2017

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The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells

30 September 2017

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The lipid phosphatase activity of PTEN is critical for its tumor supressor function

30 September 2017

1 reference

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

30 September 2017

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Reversible Inactivation of Protein-tyrosine Phosphatase 1B in A431 Cells Stimulated with Epidermal Growth Factor

30 September 2017

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Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

30 September 2017

1 reference

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

30 September 2017

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Activation of protein kinase B β and γ isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B α

30 September 2017

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Acute regulation of glucose transport in a monocyte-macrophage cell line: Glut-3 affinity for glucose is enhanced during the respiratory burst.

30 September 2017

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Superoxide formation and macrophage resistance to nitric oxide-mediated apoptosis

30 September 2017

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Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine phosphorylation

30 September 2017

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Mechanism of activation of protein kinase B by insulin and IGF-1

30 September 2017

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Requirement for generation of H2O2 for platelet-derived growth factor signal transduction

30 September 2017

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Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN.

30 September 2017

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Distinct phosphatidylinositol 3-kinase lipid products accumulate upon oxidative and osmotic stress and lead to different cellular responses

29 June 2018

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Pyrrolidine Dithiocarbamate Prevents p53 Activation and Promotes p53 Cysteine Residue Oxidation

29 June 2018

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Oxygen radicals and signaling

29 June 2018

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Adenoviral-mediated expression of MMAC/PTEN inhibits proliferation and metastasis of human prostate cancer cells.

29 June 2018

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A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis.

22 September 2018

1 reference

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Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

22 September 2018

1 reference

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The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling

22 September 2018

1 reference

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Antioxidant enzymes suppress nitric oxide production through the inhibition of NF-kappa B activation: role of H(2)O(2) and nitric oxide in inducible nitric oxide synthase expression in macrophages

22 September 2018

1 reference

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Lipopolysaccharide activates Akt in human alveolar macrophages resulting in nuclear accumulation and transcriptional activity of beta-catenin

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213768

Participation of reactive oxygen species in the lysophosphatidic acid-stimulated mitogen-activated protein kinase kinase activation pathway

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14532122

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Specific and Reversible Inactivation of Protein Tyrosine Phosphatases by Hydrogen Peroxide: Evidence for a Sulfenic Acid Intermediate and Implications for Redox Regulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14532122

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/EMBOJ/CDG513

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14532122%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14532122%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

PubMed publication ID

14532122

1 reference