Redox regulation of the epigenetic landscape in cancer: a role for metabolic reprogramming in remodeling the epigenome (Q36428635)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022407%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Redox regulation of the epigenetic landscape in cancer: a role for metabolic reprogramming in remodeling the epigenome (English)

1 reference

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9 March 2020

2

1 reference

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9 March 2020

author name string

Michael J Hitchler

series ordinal

1

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9 March 2020

publication date

26 September 2012

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022407%20AND%20SRC:MED&resulttype=core&format=json

Free Radical Biology and Medicine

9 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022407%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

volume

53

1 reference

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9 March 2020

page(s)

2178-2187

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022407%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022407%20AND%20SRC:MED&resulttype=core&format=json

Fatty acid synthase expression and esophageal cancer

9 March 2020

cites work

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30 September 2017

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Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

30 September 2017

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IDH1 and IDH2 mutation analysis in Chinese patients with acute myeloid leukemia and myelodysplastic syndrome

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Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production

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The metabolic advantage of tumor cells

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IDH1 and IDH2 mutations in pediatric acute leukemia

30 September 2017

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The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

30 September 2017

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Developing histone deacetylase inhibitors as anti-cancer therapeutics

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Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.

30 September 2017

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Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

30 September 2017

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Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma.

30 September 2017

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Mendelian genetics of rare--and not so rare--cancers

30 September 2017

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The redox basis of epigenetic modifications: from mechanisms to functional consequences.

30 September 2017

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p53 downregulates the gene expression of mitochondrial aconitase in human prostate carcinoma cells.

30 September 2017

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MTHFR, MTR, and MTRR polymorphisms in relation to p16INK4A hypermethylation in mucosa of patients with colorectal cancer

30 September 2017

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Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease

30 September 2017

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30 September 2017

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Metabolic defects provide a spark for the epigenetic switch in cancer

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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HDAC expression and clinical prognosis in human malignancies

30 September 2017

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30 September 2017

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30 September 2017

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An epigenetic perspective on the free radical theory of development

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases

30 September 2017

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30 September 2017

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Mechanism and significance of increased glutathione level in human hepatocellular carcinoma and liver regeneration

30 September 2017

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The quantitatively important relationship between homocysteine metabolism and glutathione synthesis by the transsulfuration pathway and its regulation by redox changes

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30 September 2017

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Glucose deprivation-induced oxidative stress in human tumor cells. A fundamental defect in metabolism?

30 September 2017

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The Hallmarks of Cancer

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Expression and functional interaction of the catalytic and regulatory subunits of human methionine adenosyltransferase in mammalian cells

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Circular Permutations in the Molecular Evolution of DNA Methyltransferases

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Superoxide radical and iron modulate aconitase activity in mammalian cells

30 September 2017

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DNA adduct 8-hydroxyl-2'-deoxyguanosine (8-hydroxyguanine) affects function of human DNA methyltransferase

30 September 2017

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S-adenosyl-L-methionine synthetase and methionine metabolism deficiencies in cirrhosis

30 September 2017

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Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells

30 September 2017

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The presence of 5-hydroxymethylcytosine in animal deoxyribonucleic acid

30 September 2017

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Mutator phenotype may be required for multistage carcinogenesis

30 September 2017

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The role of cysteine-150 in the structure and activity of rat liver S-adenosyl-L-methionine synthetase

30 September 2017

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Deviant energetic metabolism of glycolytic cancer cells

30 September 2017

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Role of superoxide dismutase in cancer: a review

30 September 2017

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The polymorphisms in methylenetetrahydrofolate reductase, methionine synthase, methionine synthase reductase, and the risk of colorectal cancer

30 September 2017

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The Role of Mitochondrial NADPH-Dependent Isocitrate Dehydrogenase in Cancer Cells

28 June 2018

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Breathless cancer cells get fat on glutamine

28 June 2018

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Active DNA demethylation by oxidation and repair

28 June 2018

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

28 June 2018

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Changes in S-adenosylmethionine synthetase in human liver cancer: molecular characterization and significance

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Correlation between S-adenosyl-L-methionine content and production of c-myc, c-Ha-ras, and c-Ki-ras mRNA transcripts in the early stages of rat liver carcinogenesis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508253

Cell division in normal and transformed cells: The possible role of superoxide and hydrogen peroxide

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508253

The effect of growth conditions on NAD+ and NADH concentrations and the NAD+:NADH ratio in normal and transformed fibroblasts.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508253

Protooncogene methylation and expression in regenerating liver and preneoplastic liver nodules induced in the rat by diethylnitrosamine: effect of variations of S-adenosylmethionine:S-adenosylhomocysteine ratio.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508253

Inhibition of glutathione synthesis in the liver leads to S-adenosyl-L-methionine synthetase reduction

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508253

Comparative effects of L-methionine, S-adenosyl-L-methionine and 5'-methylthioadenosine on the growth of preneoplastic lesions and DNA methylation in rat liver during the early stages of hepatocarcinogenesis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508253

Modulation of rat liver S-adenosylmethionine synthetase activity by glutathione

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508253

Chemoprevention of rat liver carcinogenesis by S-adenosyl-L-methionine: a long-term study

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508253

Glycolytic metabolism in cultured cells of the nervous system. II. Regulation of pyruvate and lactate metabolism in the C-6 glioma cell line

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508253

Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter.

27 July 2018

1 reference

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Redox signaling in cancer biology.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508253

Global histone modification patterns predict risk of prostate cancer recurrence

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508253

The presence of acetyl groups of histones

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508253

5-Methylcytosine attack by hydroxyl free radicals and during carbon tetrachloride promoted liver microsomal lipid peroxidation: structure of reaction products.

21 September 2018

1 reference

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Fatty acid synthase is a predictive marker for aggressiveness in meningiomas

21 September 2018

1 reference

12 December 2020

Global histone modification pattern associated with recurrence and disease-free survival in non-small cell lung cancer patients

1 reference

12 December 2020

Glutathione depletion-induced thymidylate insufficiency for DNA repair synthesis

1 reference

12 December 2020

Fatty acid synthase hyperactivation in human colorectal cancer: relationship with tumor side and sex

1 reference

12 December 2020

Mechanism of reductive activation of cobalamin-dependent methionine synthase: an electron paramagnetic resonance spectroelectrochemical study

1 reference

12 December 2020

S-adenosylmethionine treatment prevents carbon tetrachloride-induced S-adenosylmethionine synthetase inactivation and attenuates liver injury

1 reference

12 December 2020

Methyl-donor deficiency due to chemically induced glutathione depletion

1 reference

12 December 2020

Alterations of DNA methylation by glutathione depletion

1 reference

12 December 2020

10.1016/J.FREERADBIOMED.2012.09.028

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022407%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022407%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022407%20AND%20SRC:MED&resulttype=core&format=json