Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia (Q29616650)

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22101433

30 April 2017

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Metallo CM

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22101433

30 April 2017

Gameiro PA

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30 April 2017

Bell EL

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30 April 2017

Mattaini KR

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30 April 2017

Yang J

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30 April 2017

Hiller K

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30 April 2017

Jewell CM

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30 April 2017

Johnson ZR

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30 April 2017

Irvine DJ

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30 April 2017

Guarente L

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30 April 2017

Kelleher JK

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30 April 2017

Vander Heiden MG

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30 April 2017

Iliopoulos O

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30 April 2017

Stephanopoulos G

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22101433

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22101433

30 April 2017

language of work or name

1 reference

30 April 2017

publication date

20 November 2011

1 reference

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30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22101433

30 April 2017

volume

481

1 reference

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30 April 2017

page(s)

380-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22101433

30 April 2017

issue

7381

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22101433

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

30 April 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

HIF-1: upstream and downstream of cancer metabolism

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

ATP-citrate lyase links cellular metabolism to histone acetylation

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

Molecular basis of the VHL hereditary cancer syndrome

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

Proton-translocating transhydrogenase and NAD- and NADP-linked isocitrate dehydrogenases operate in a substrate cycle which contributes to fine regulation of the tricarboxylic acid cycle activity in mitochondria

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

Isotopomer analysis of citric acid cycle and gluconeogenesis in rat liver. Reversibility of isocitrate dehydrogenase and involvement of ATP-citrate lyase in gluconeogenesis

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

Pyruvate carboxylase is required for glutamine-independent growth of tumor cells

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

Quiescent fibroblasts exhibit high metabolic activity.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

Small-molecule inhibitors of HIF-2a translation link its 5'UTR iron-responsive element to oxygen sensing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

Identification of metabolic fluxes in hepatic cells from transient 13C-labeling experiments: Part II. Flux estimation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

Metabolic networks in motion: 13C-based flux analysis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710581

ATP citrate lyase inhibition can suppress tumor cell growth

3 June 2018

1 reference

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Cell and environment interactions in tumor microregions: the multicell spheroid model

3 June 2018

1 reference

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Isotopomer spectral analysis of triglyceride fatty acid synthesis in 3T3-L1 cells

3 June 2018

1 reference

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Defective RNA ribose synthesis in fibroblasts from patients with thiamine-responsive megaloblastic anemia (TRMA).

3 June 2018

1 reference

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An elementary metabolite unit (EMU) based method of isotopically nonstationary flux analysis.

21 January 2018

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Tumour suppression by the human von Hippel-Lindau gene product

21 January 2018

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T cell receptor antagonist peptides induce positive selection

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE10602

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10602

Determination of confidence intervals of metabolic fluxes estimated from stable isotope measurements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10602

Elementary metabolite units (EMU): a novel framework for modeling isotopic distributions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10602

Effect of anaplerotic fluxes and amino acid availability on hepatic lipoapoptosis

21 January 2018

1 reference

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Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10602

Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10602

[The enzymatic properties of isocitric dehydrogenase]

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22101433

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evidence for an InsP3-gated channel protein in isolated rat olfactory cilia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10602

inferred from DOI database lookup

7 January 2021

based on heuristic

Correction of 13C mass isotopomer distributions for natural stable isotope abundance

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10602

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22101433

30 April 2017

Dimensions Publication ID

100387

1053544093

0 references

100387

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22101433

2 references

30 April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22101433

2 references

30 April 2017