Role of β-hairpin formation in aggregation: the self-assembly of the amyloid-β(25-35) peptide. (Q36150710)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22947874%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Role of β-hairpin formation in aggregation: the self-assembly of the amyloid-β(25-35) peptide (English)

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12 February 2020

1 reference

1

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12 February 2020

2

Joan-Emma Shea

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12 February 2020

language of work or name

English

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publication date

1 August 2012

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12 February 2020

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12 February 2020

volume

103

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12 February 2020

issue

3

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12 February 2020

page(s)

576-586

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GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

12 February 2020

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Subcellular and metabolic examination of amyloid-beta peptides in Alzheimer disease pathogenesis: evidence for Abeta(25-35).

2 October 2017

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2 October 2017

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Structural characterization of a soluble amyloid beta-peptide oligomer.

2 October 2017

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Replica exchange simulations of the thermodynamics of Abeta fibril growth

2 October 2017

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2 October 2017

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Role of the familial Dutch mutation E22Q in the folding and aggregation of the 15-28 fragment of the Alzheimer amyloid-beta protein.

2 October 2017

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Stabilization of a -hairpin in monomeric Alzheimer's amyloid- peptide inhibits amyloid formation

2 October 2017

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Alzheimer's Abeta peptides containing an isostructural backbone mutation afford distinct aggregate morphologies but analogous cytotoxicity. Evidence for a common low-abundance toxic structure(s)?

2 October 2017

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Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils

2 October 2017

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Structural reorganisation and potential toxicity of oligomeric species formed during the assembly of amyloid fibrils

2 October 2017

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Generic cell dysfunction in neurodegenerative disorders: role of surfaces in early protein misfolding, aggregation, and aggregate cytotoxicity.

2 October 2017

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Monomer adds to preformed structured oligomers of Abeta-peptides by a two-stage dock-lock mechanism.

2 October 2017

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Effects of solvent on the structure of the Alzheimer amyloid-beta(25-35) peptide

2 October 2017

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Protein misfolding, functional amyloid, and human disease

2 October 2017

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The stability of monomeric intermediates controls amyloid formation: Abeta25-35 and its N27Q mutant

2 October 2017

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2 October 2017

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Opinion: What is the role of protein aggregation in neurodegeneration?

2 October 2017

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Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Protein aggregation: folding aggregates, inclusion bodies and amyloid

2 October 2017

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2 October 2017

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2 October 2017

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Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25-35 region to aggregation and neurotoxicity

2 October 2017

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

2 October 2017

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2 October 2017

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2 October 2017

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Oligomers of the prion protein fragment 106-126 are likely assembled from beta-hairpins in solution, and methionine oxidation inhibits assembly without altering the peptide's monomeric conformation

2 October 2017

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2 July 2018

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2 July 2018

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23 September 2018

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23 September 2018

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23 September 2018

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23 September 2018

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23 September 2018

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23 September 2018

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23 September 2018

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Amyloid-beta(29-42) dimer formations studied by a multicanonical-multioverlap molecular dynamics simulation.

23 September 2018

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The structure of the Alzheimer amyloid beta 10-35 peptide probed through replica-exchange molecular dynamics simulations in explicit solvent.

23 September 2018

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Folding landscapes of the Alzheimer amyloid-beta(12-28) peptide.

23 September 2018

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Prefibrillar amyloid aggregates could be generic toxins in higher organisms.

23 September 2018

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Abeta(31-35) and Abeta(25-35) fragments of amyloid beta-protein induce cellular death through apoptotic signals: Role of the redox state of methionine-35.

23 September 2018

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Abeta(31-35) peptide induce apoptosis in PC 12 cells: contrast with Abeta(25-35) peptide and examination of underlying mechanisms.

23 September 2018

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Beta-hairpin conformation of fibrillogenic peptides: structure and alpha-beta transition mechanism revealed by molecular dynamics simulations

23 September 2018

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Kinetic analysis of beta-amyloid fibril elongation

23 September 2018

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Solution NMR studies of the A beta(1-40) and A beta(1-42) peptides establish that the Met35 oxidation state affects the mechanism of amyloid formation

23 September 2018

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23 September 2018

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23 September 2018

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23 September 2018

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23 September 2018

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Suppression of mitochondrial succinate dehydrogenase, a primary target of beta-amyloid, and its derivative racemized at Ser residue.

23 September 2018

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23 September 2018

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21 October 2018

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21 October 2018

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12 December 2020

Conformations of beta-amyloid in solution

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12 December 2020

Studies of the effects of fragment (25-35) of beta-amyloid peptide on the behavior of rats in a radial maze

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Studies of the effects of central administration of beta-amyloid peptide (25-35): pathomorphological changes in the Hippocampus and impairment of spatial memory

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Disordered versus fibril-like amyloid β (25-35) dimers in water: structure and thermodynamics

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12 February 2020

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