From abnormal hippocampal synaptic plasticity in down syndrome mouse models to cognitive disability in down syndrome (Q36111747)

12 August 2017

8 references

22 April 2019

25 April 2019

24 June 2019

12 September 2019

12 October 2019

6 July 2020

6 April 2021

26 October 2022

From abnormal hippocampal synaptic plasticity in down syndrome mouse models to cognitive disability in down syndrome (English)

1 reference

12 August 2017

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6 references

22 April 2019

25 April 2019

24 June 2019

12 September 2019

12 October 2019

6 July 2020

6 references

22 April 2019

25 April 2019

24 June 2019

12 September 2019

12 October 2019

6 July 2020

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12 September 2019

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12 October 2019

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6 April 2021

1 reference

Nathan Cramer

1

1 reference

PMCID

3403629

12 August 2017

Zygmunt Galdzicki

series ordinal

2

1 reference

PMCID

3403629

12 August 2017

language of work or name

1 reference

12 July 2012

9 references

12 August 2017

22 April 2019

25 April 2019

24 June 2019

12 September 2019

12 October 2019

6 July 2020

6 April 2021

26 October 2022

9 references

12 August 2017

22 April 2019

25 April 2019

24 June 2019

12 September 2019

12 October 2019

6 July 2020

6 April 2021

26 October 2022

2012

1 reference

12 August 2017

101542

1 reference

Creative Commons Attribution 3.0 Unported

12 August 2017

8 references

22 April 2019

25 April 2019

24 June 2019

12 September 2019

12 October 2019

6 July 2020

6 April 2021

on focus list of Wikimedia project

26 October 2022

copyright status

copyrighted

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cites work

Mechanisms of CaMKII action in long-term potentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Trisomy of the G protein-coupled K+ channel gene, Kcnj6, affects reward mechanisms, cognitive functions, and synaptic plasticity in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Environmental enrichment decreases GABAergic inhibition and improves cognitive abilities, synaptic plasticity, and visual functions in a mouse model of Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Trisomy 21 and early brain development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Myeloid leukemia in Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Exaggerated NMDA mediated LTD in a mouse model of Down syndrome and pharmacological rescuing by memantine

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Chronic Treatment with a Promnesiant GABA-A α5-Selective Inverse Agonist Increases Immediate Early Genes Expression during Memory Processing in Mice and Rectifies Their Expression Levels in a Down Syndrome Mouse Model

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Alterations of brain circuits in Down syndrome murine models

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Functional magnetic resonance imaging of cognitive processing in young adults with Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

On the promise of pharmacotherapies targeted at cognitive and neurodegenerative components of Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Environmental enrichment rescues postnatal neurogenesis defect in the male and female Ts65Dn mouse model of Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

The use of mouse models to understand and improve cognitive deficits in Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Specific targeting of the GABA-A receptor α5 subtype by a selective inverse agonist restores cognitive deficits in Down syndrome mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down syndrome: activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

GABAB-GIRK2-mediated signaling in Down syndrome.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Down's syndrome-like cardiac developmental defects in embryos of the transchromosomic Tc1 mouse

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Neuropsychological components of intellectual disability: the contributions of immediate, working, and associative memory

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Prevalence of congenital heart defects and persistent pulmonary hypertension of the neonate with Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Dendritic spines: the stuff that memories are made of?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

AMPA receptor incorporation into synapses during LTP: the role of lateral movement and exocytosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Evaluation of early stimulation programs for enhancing brain development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Balancing structure and function at hippocampal dendritic spines

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Place cells, grid cells, and the brain's spatial representation system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Sleep and EEG features in genetic models of Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Neurotransmitters and the development of neuronal circuits

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Synaptic plasticity, memory and the hippocampus: a neural network approach to causality.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Behavioral functions of the CA3 subregion of the hippocampus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Convergence of entorhinal and CA3 inputs onto pyramidal neurons and interneurons in hippocampal area CA1--an anatomical study in the rat.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

The postsynaptic architecture of excitatory synapses: a more quantitative view

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Responsive teaching: early intervention for children with Down syndrome and other disabilities

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

The proteins of human chromosome 21.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Spike timing-dependent plasticity: from synapse to perception.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Deficits in hippocampal CA1 LTP induced by TBS but not HFS in the Ts65Dn mouse: a model of Down syndrome.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Mitogen-activated protein kinases in synaptic plasticity and memory.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Structural basis of long-term potentiation in single dendritic spines

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Understanding mental retardation in Down's syndrome using trisomy 16 mouse models

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Down's syndrome: a genetic disorder in biobehavioral perspective

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Alterations of neocortical pyramidal cell phenotype in the Ts65Dn mouse model of Down syndrome: effects of environmental enrichment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Introduction. Long-term potentiation and structure of the issue

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

The neuropsychology of Down syndrome: evidence for hippocampal dysfunction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Fetal life in Down syndrome starts with normal neuronal density but impaired dendritic spines and synaptosomal structure

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Trk receptors: mediators of neurotrophin action

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

2 October 2017

Consolidation of memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Behavioral phenotype of individuals with Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Recruitment of long-lasting and protein kinase A-dependent long-term potentiation in the CA1 region of hippocampus requires repeated tetanization.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Ca2+/calmodulin-kinase II enhances channel conductance of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate type glutamate receptors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Identification of the Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in the alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate-type glutamate receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

A requirement for the mitogen-activated protein kinase cascade in hippocampal long term potentiation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

A synaptic model of memory: long-term potentiation in the hippocampus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Segmental trisomy as a mouse model for Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Development of the superior temporal neocortex is anomalous in trisomy 21.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Requirement of a critical period of transcription for induction of a late phase of LTP.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Potentiated transmission and prevention of further LTP by increased CaMKII activity in postsynaptic hippocampal slice neurons

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Autophosphorylation reversibly regulates the Ca2+/calmodulin-dependence of Ca2+/calmodulin-dependent protein kinase II.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Segmental trisomy of murine chromosome 16: a new model system for studying Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Growth and development of the brain in Down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Pyramidal cell abnormalities in the motor cortex of a child with Down's syndrome. A Golgi study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Normal and Aberrant Neuronal Development in the Cerebral Cortex of Human Fetus and Young Infant

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

A volumetric magnetic resonance imaging study of brain structures in children with Down syndrome.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

An increase in basal BDNF provokes hyperactivation of the Akt-mammalian target of rapamycin pathway and deregulation of local dendritic translation in a mouse model of Down's syndrome.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Cranial base, maxillary and mandibular morphology in Down syndrome

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Locally dynamic synaptic learning rules in pyramidal neuron dendrites

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Hippocampal synaptic metaplasticity requires inhibitory autophosphorylation of Ca2+/calmodulin-dependent kinase II.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Behavioral comparison of 4 and 6 month-old Ts65Dn mice: age-related impairments in working and reference memory

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

The MAPK/ERK cascade targets both Elk-1 and cAMP response element-binding protein to control long-term potentiation-dependent gene expression in the dentate gyrus in vivo.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Protein kinase A inhibitors prevent the maintenance of hippocampal long-term potentiation.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Dendritic and histochemical development and ageing in patients with Down's syndrome

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

A mouse model for Down syndrome exhibits learning and behaviour deficits.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Dendritic atrophy in children with Down's syndrome.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Calcium/calmodulin-independent autophosphorylation sites of calcium/calmodulin-dependent protein kinase II. Studies on the effect of phosphorylation of threonine 305/306 and serine 314 on calmodulin binding using synthetic peptides

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Down syndrome children often have brain with maturation delay, retardation of growth, and cortical dysgenesis.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Brain growth in Down syndrome subjects 15 to 22 weeks of gestational age and birth to 60 months.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice.

2 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Fetal Down syndrome brains exhibit aberrant levels of neurotransmitters critical for normal brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Synaptic development in the human fetus: a morphometric analysis of normal and Down's syndrome neocortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Neuroanatomy of Down's syndrome: a high-resolution MRI study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Amygdala and hippocampal volumes in children with Down syndrome: a high-resolution MRI study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Relation of corpus callosum and hippocampal size to age in nondemented adults with Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Early impairment of synaptic plasticity in patients with Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Abnormal fMRI activation pattern during story listening in individuals with Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Pattern of increased cerebral FDG uptake in Down syndrome patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Pharmacotherapy for cognitive impairment in a mouse model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Effects of chronic administration of SGS-111 during adulthood and during the pre- and post-natal periods on the cognitive deficits of Ts65Dn mice, a model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Rescue of synaptic failure and alleviation of learning and memory impairments in a trisomic mouse model of down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Synaptic and cognitive abnormalities in mouse models of Down syndrome: exploring genotype-phenotype relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Synaptic structural abnormalities in the Ts65Dn mouse model of Down Syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Memantine normalizes several phenotypic features in the Ts65Dn mouse model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Intracellular injections of EGTA block induction of hippocampal long-term potentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Plasticity-specific phosphorylation of CaMKII, MAP-kinases and CREB during late-LTP in rat hippocampal slices in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Rescue of neurological deficits in a mouse model for Angelman syndrome by reduction of alphaCaMKII inhibitory phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Altered signaling pathways underlying abnormal hippocampal synaptic plasticity in the Ts65Dn mouse model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Involvement of a postsynaptic protein kinase A substrate in the expression of homosynaptic long-term depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

NMDA induces long-term synaptic depression and dephosphorylation of the GluR1 subunit of AMPA receptors in hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Protein kinase A phosphorylates Down syndrome critical region 1 (RCAN1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Regulation of NMDA channel function by endogenous Ca(2+)-dependent phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Protein kinase C and ERK involvement in dendritic spine plasticity in cultured rodent hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

BDNF regulates the translation of a select group of mRNAs by a mammalian target of rapamycin-phosphatidylinositol 3-kinase-dependent pathway during neuronal development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Transport of brain-derived neurotrophic factor across the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Ts65Dn, a mouse model of Down syndrome, exhibits increased GABAB-induced potassium current.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Compartment-dependent colocalization of Kir3.2-containing K+ channels and GABAB receptors in hippocampal pyramidal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Cortical sources of EEG rhythms are abnormal in down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Differential effects of environmental enrichment on behavior and learning of male and female Ts65Dn mice, a model for Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Behavioral, cognitive and biochemical responses to different environmental conditions in male Ts65Dn mice, a model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

The hippocampus in Down's syndrome.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Dendrites, dementia and the Down syndrome.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403629

Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity

23 September 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F101542

Abnormal synaptic plasticity in the Ts1Cje segmental trisomy 16 mouse model of Down syndrome

21 January 2018

1 reference

12 December 2020

Phenotypic and dermatological manifestations in Down Syndrome

1 reference

12 December 2020

Diffusion laws in dendritic spines

1 reference

12 December 2020

Passive propagation of LTD to stratum oriens-alveus inhibitory neurons modulates the temporoammonic input to the hippocampal CA1 region

1 reference

12 December 2020

Identifiers

DOI

10.1155/2012/101542

1 reference

12 August 2017

1 reference

12 August 2017

1 reference

PMCID

3403629