Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice. (Q31104439)

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26 December 2019

title

Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice (English)

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26 December 2019

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1

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26 December 2019

Randall J. Roper

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26 December 2019

author name string

Crystal L Sengstaken

3

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26 December 2019

Elizabeth A Peterson

4

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26 December 2019

Veronica Aquino

5

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26 December 2019

Zygmunt Galdzicki

6

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26 December 2019

Richard Siarey

7

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26 December 2019

Mikhail Pletnikov

8

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26 December 2019

Timothy H Moran

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26 December 2019

Roger H Reeves

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26 December 2019

publication date

5 March 2007

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26 December 2019

published in

Human Molecular Genetics

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26 December 2019

volume

16

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26 December 2019

page(s)

774-782

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26 December 2019

issue

7

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Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome

26 December 2019

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Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities

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A chromosome 21 critical region does not cause specific Down syndrome phenotypes.

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Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.

21 January 2018

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21 January 2018

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Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome

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Identifiers

DOI

10.1093/HMG/DDM022

1 reference

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26 December 2019

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