A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions (Q30495192)

2 October 2017

A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions (English)

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2 October 2017

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15

George Stoica

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2 October 2017

Tao Yu

1

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2 October 2017

Zhongyou Li

2

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2 October 2017

Zhengping Jia

3

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2 October 2017

Steven J Clapcote

4

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2 October 2017

Chunhong Liu

5

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2 October 2017

Shaomin Li

6

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2 October 2017

Suhail Asrar

7

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2 October 2017

Annie Pao

8

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2 October 2017

Rongqing Chen

9

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2 October 2017

Ni Fan

10

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2 October 2017

Sandra Carattini-Rivera

11

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2 October 2017

Allison R Bechard

12

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2 October 2017

Shoshana Spring

13

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2 October 2017

R Mark Henkelman

14

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2 October 2017

Sei-Ichi Matsui

16

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2 October 2017

Norma J Nowak

17

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2 October 2017

John C Roder

18

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2 October 2017

Chu Chen

19

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2 October 2017

Allan Bradley

20

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2 October 2017

Y Eugene Yu

21

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2 October 2017

4 May 2010

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2 October 2017

Human Molecular Genetics

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2 October 2017

19

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2 October 2017

2780-2791

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2 October 2017

14

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A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Deficits in hippocampal CA1 LTP induced by TBS but not HFS in the Ts65Dn mouse: a model of Down syndrome.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Identification and characterization of a new Down syndrome model, Ts[Rb(12.1716)]2Cje, resulting from a spontaneous Robertsonian fusion between T(171)65Dn and mouse chromosome 12.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Down syndrome and genetics - a case of linked histories.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Chromosome 21 and down syndrome: from genomics to pathophysiology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Survey of embryonic stem cell line source strains in the water maze reveals superior reversal learning of 129S6/SvEvTac mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Long-Term Potentiation and Memory

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

The neuropsychology of Down syndrome: evidence for hippocampal dysfunction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Comparative analysis of an improved thioflavin-s stain, Gallyas silver stain, and immunohistochemistry for neurofibrillary tangle demonstration on the same sections.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Chromosome 21: from sequence to applications

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Behavioral phenotype of individuals with Down syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Synaptic plasticity and memory: an evaluation of the hypothesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Long-term potentiation--a decade of progress?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Thirteen years of manipulating the mouse genome: a personal history

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Embryonic lethality and tumorigenesis caused by segmental aneuploidy on mouse chromosome 11.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

The neuropsychology of mental retardation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Enhanced LTP in mice deficient in the AMPA receptor GluR2.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Long-term depression in hippocampus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

A synaptic model of memory: long-term potentiation in the hippocampus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Hippocampus, theta, and spatial memory

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

A mouse model for Down syndrome exhibits learning and behaviour deficits.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Chromosome engineering in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Neuropsychological evaluation of adults with Down's syndrome: patterns of selective impairment in non-demented old adults.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Isokinetic arm and leg strength of adults with Down syndrome: a comparative study

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Down's syndrome with hydrocephalus treated by compressive head binding

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Hydrocephalus in Down's syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Chromosomal abnormality rates at amniocentesis and in live-born infants

28 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Ts65Dn -- localization of the translocation breakpoint and trisomic gene content in a mouse model for Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Ca2+-dependent induction of TRPM2 currents in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Duplication of the entire 22.9 Mb human chromosome 21 syntenic region on mouse chromosome 16 causes cardiovascular and gastrointestinal abnormalities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Down syndrome mouse models are looking up.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Down syndrome--recent progress and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

DYRK1A BAC transgenic mice show altered synaptic plasticity with learning and memory defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

A behavioral assessment of Ts65Dn mice: a putative Down syndrome model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Down syndrome with congenital hydrocephalus: case report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Enlarged brain ventricles and impaired neurogenesis in the Ts1Cje and Ts2Cje mouse models of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Trisomy represses Apc Min -mediated tumours in mouse models of Down’s syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Mutagenic insertion and chromosome engineering resource (MICER).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Effects of the rd1 mutation and host strain on hippocampal learning in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Mildly impaired water maze performance in male Fmr1 knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

The use of behavioral test batteries: effects of training history.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Oxidative stress induced by intense and exhaustive exercise impairs murine cognitive function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Abnormal spine morphology and enhanced LTP in LIMK-1 knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Neuronal differentiation of NTE-deficient embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

BACE1 inhibition reduces endogenous Abeta and alters APP processing in wild-type mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

Male pachytene pairing in single and double translocation heterozygotes and spermatogenic impairment in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ179

App gene dosage modulates endosomal abnormalities of Alzheimer's disease in a segmental trisomy 16 mouse model of down syndrome

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Contextual and cued fear conditioning in C57BL/6J and DBA/2J mice: context discrimination and the effects of retention interval.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Anomalies in Down syndrome individuals in a large population-based registry

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893810

Improved national prevalence estimates for 18 selected major birth defects--United States, 1999-2001

26 November 2018

1 reference

12 December 2020

Gene targeting in embryonic stem cells

1 reference

12 December 2020

Strength deficit of knee extensor muscles of individuals with Down syndrome from childhood to adolescence

1 reference

12 December 2020

Evolutionary breakpoints on human chromosome 21

1 reference

12 December 2020

Measurements of neuromuscular tone and strength in Down's syndrome children

1 reference

12 December 2020

A reciprocal autosomal translocation which causes male sterility in the mouse also impairs oogenesis.

1 reference

12 December 2020

[Apropos of a case of combined mongolism and hydrocephalus. Discussion of the etiological factor.]

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDQ179

1 reference

release_dm4hloeklrhwjp6rusyq2ushbi

2 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/dm4hloeklrhwjp6rusyq2ushbi

24 November 2022

mapped directly with Wikidata item

1 reference

2 October 2017

1 reference