The Interactions between Insulin and Androgens in Progression to Castrate-Resistant Prostate Cancer (Q35882782)

10 August 2017

The Interactions between Insulin and Androgens in Progression to Castrate-Resistant Prostate Cancer (English)

1 reference

10 August 2017

1 reference

Jennifer H Gunter

1

0 references

Colleen Nelson

series ordinal

5

object named as

Colleen C Nelson

1 reference

10 August 2017

Amy A Lubik

2

1 reference

PMCID

3324133

10 August 2017

Ian McKenzie

series ordinal

3

1 reference

PMCID

3324133

10 August 2017

Michael Pollak

series ordinal

4

1 reference

10 August 2017

3 April 2012

1 reference

10 August 2017

1 reference

10 August 2017

2012

1 reference

10 August 2017

248607

1 reference

Creative Commons Attribution 3.0 Unported

10 August 2017

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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11 July 2018

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Thiazolidinediones and metformin associated with improved survival of diabetic prostate cancer patients.

11 July 2018

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Docosahexaenoic acid selectively induces human prostate cancer cell sensitivity to oxidative stress through modulation of NF-κB.

11 July 2018

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CaM kinase kinase beta-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells

11 July 2018

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11 July 2018

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11 July 2018

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Integrative genomic profiling of human prostate cancer

11 July 2018

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Diabetes mellitus, hyperglycaemia and cancer

11 July 2018

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Insulin--carcinogen or mitogen? Preclinical and clinical evidence from prostate, breast, pancreatic, and colorectal cancer research

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer

11 July 2018

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11 July 2018

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11 July 2018

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Inactivation of AMPK alters gene expression and promotes growth of prostate cancer cells.

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer

11 July 2018

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The role of exercise and PGC1alpha in inflammation and chronic disease

11 July 2018

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Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth

11 July 2018

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Hypothalamic CaMKK2 contributes to the regulation of energy balance

11 July 2018

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Targeting AMPK: a new therapeutic opportunity in breast cancer

11 July 2018

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Adipocytokines, obesity, and insulin resistance during combined androgen blockade for prostate cancer

11 July 2018

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Obesity, metabolic syndrome, and prostate cancer

11 July 2018

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The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.

11 July 2018

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Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells

11 July 2018

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Cooperative interactions between androgen receptor (AR) and heat-shock protein 27 facilitate AR transcriptional activity

11 July 2018

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AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

11 July 2018

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Obesity and prostate cancer: epidemiology and clinical implications

11 July 2018

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Differential regulation of clusterin and its isoforms by androgens in prostate cells

11 July 2018

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Transcriptional regulation by insulin: from the receptor to the gene.

11 July 2018

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Obesity and cancer risk: the role of the insulin-IGF axis

11 July 2018

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Fatty acid oxidation is a dominant bioenergetic pathway in prostate cancer

11 July 2018

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Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor

11 July 2018

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Adiponectin--a key adipokine in the metabolic syndrome

11 July 2018

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Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer

11 July 2018

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Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis

11 July 2018

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Rho GTPases: biochemistry and biology

11 July 2018

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Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors

11 July 2018

1 reference

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Metformin and reduced risk of cancer in diabetic patients

11 July 2018

1 reference

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Mechanisms of the development of androgen independence in prostate cancer

11 July 2018

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Androgen receptor cross-talk with cell signalling pathways

11 July 2018

1 reference

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Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3324133

AMP-activated protein kinase activators can inhibit the growth of prostate cancer cells by multiple mechanisms

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3324133

The LKB1 tumor suppressor negatively regulates mTOR signaling

11 July 2018

1 reference

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Intermittent androgen deprivation therapy for prostate cancer

11 July 2018

1 reference

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Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition

11 July 2018

1 reference

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Insulin Augmentation of 17α-Hydroxylase Activity Is Mediated by Phosphatidyl Inositol 3-Kinase But Not Extracellular Signal-Regulated Kinase-1/2 in Human Ovarian Theca Cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3324133

Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3324133

A history of prostate cancer treatment

11 July 2018

1 reference

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Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

11 July 2018

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Role of AMP-activated protein kinase in mechanism of metformin action

11 July 2018

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Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen.

11 July 2018

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Insulin regulation of human ovarian androgens

11 July 2018

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Body size and prostate cancer: a 20-year follow-up study among 135006 Swedish construction workers

11 July 2018

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Interrelation between plasma testosterone and plasma insulin in healthy adult men: the Telecom Study

11 July 2018

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High-affinity insulin binding to an atypical insulin-like growth factor-I receptor in human breast cancer cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3324133

Hyperinsulinaemia: a prospective risk factor for lethal clinical prostate cancer

11 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Association between prostate-specific antigen and leptin, adiponectin, HbA1c or C-peptide among African-American and Caucasian men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Decreased testosterone and dehydroepiandrosterone sulfate concentrations are associated with increased insulin and glucose concentrations in nondiabetic men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Sex hormones, inflammation and the metabolic syndrome: a population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Partial androgen deficiency in aging type 2 diabetic men and its relationship to glycemic control

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Metabolic profiling of urine in young obese men using ultra performance liquid chromatography and Q-TOF mass spectrometry (UPLC/Q-TOF MS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Alterations in cholesterol regulation contribute to the production of intratumoral androgens during progression to castration-resistant prostate cancer in a mouse xenograft model

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Insulin sensitivity during combined androgen blockade for prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Hyperglycemia and insulin resistance in men with prostate carcinoma who receive androgen-deprivation therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Low testosterone levels are common and associated with insulin resistance in men with diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

The influence of age on bioavailable and free testosterone is independent of body mass index and glucose levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Frequent occurrence of hypogonadotropic hypogonadism in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Characteristics of secondary, primary, and compensated hypogonadism in aging men: evidence from the European Male Ageing Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Hypothalamic interleukin-1 beta and tumor necrosis factor-alpha, but not interleukin-6, mediate the endotoxin-induced suppression of the reproductive axis in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

The health-promoting school: what role for nursing?

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Effects of testosterone supplementation on markers of the metabolic syndrome and inflammation in hypogonadal men with the metabolic syndrome: the double-blinded placebo-controlled Moscow study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Acute sex steroid withdrawal reduces insulin sensitivity in healthy men with idiopathic hypogonadotropic hypogonadism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

The effect of androgen deprivation therapy on fasting serum lipid and glucose parameters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Increased adiposity in DNA binding-dependent androgen receptor knockout male mice associated with decreased voluntary activity and not insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

The CAG repeat polymorphism in the androgen receptor gene modulates body fat mass and serum concentrations of leptin and insulin in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

PI3K-AKT-mTOR pathway is dominant over androgen receptor signaling in prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Diabetes mellitus and prostate cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Testosterone, obesity and insulin resistance in young males: evidence for an association between gonadal dysfunction and insulin resistance during puberty.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3324133

Testosterone administration suppresses adiponectin levels in men.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3324133

Body mass index, height, and prostate cancer mortality in two large cohorts of adult men in the United States.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3324133

Attenuated luteinizing hormone (LH) pulse amplitude but normal LH pulse frequency, and its relation to plasma androgens in hypogonadism of obese men.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3324133

Essential fatty acids enhance free radical generation and lipid peroxidation to induce apoptosis of tumor cells

24 September 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Prostate cancer risk in the Swedish AMORIS study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Low levels of apolipoprotein A-I and HDL are associated with risk of prostate cancer in the Swedish AMORIS study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F248607

Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer

21 January 2018

1 reference

12 December 2020

Metformin and the incidence of prostate cancer in patients with type 2 diabetes

1 reference

12 December 2020

Does diabetes mellitus increase the risk of high-grade prostate cancer in patients undergoing radical prostatectomy?

1 reference

12 December 2020

Insulin Increases De Novo Steroidogenesis in Prostate Cancer Cells

1 reference

12 December 2020

Serum prostate-specific antigen levels in men with type 2 diabetes

1 reference

12 December 2020

Presence of the metabolic syndrome is associated with shorter time to castration-resistant prostate cancer

1 reference

12 December 2020

Obesity in men: the hypogonadal-estrogen receptor relationship and its effect on glucose homeostasis

1 reference

12 December 2020

Interactions among peroxisome proliferator activated receptor-gamma, insulin signaling pathways, and steroidogenic acute regulatory protein in human ovarian cells

1 reference

12 December 2020

Obesity and the risk of prostate cancer

1 reference

12 December 2020

Obesity and prostate cancer

1 reference

12 December 2020

Identifiers

DOI

10.1155/2012/248607

1 reference

10 August 2017

1 reference

10 August 2017

1 reference

PMCID

3324133