The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis (Q39538459)

12 September 2017

The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis (English)

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12 September 2017

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1

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19

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Rory Stark

5

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James Hadfield

James Hadfield

17

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Gina M DeNicola

Gina M Denicola

14

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Scott K Lyons

Scott K Lyons

20

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Andy G. Lynch

Andy Lynch

2

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Madhu Basetti

Basetti Madhu

9

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David E. Neal

David E Neal

25

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author name string

Antonio Ramos-Montoya

3

1 reference

12 September 2017

Joan Boren

4

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12 September 2017

Ladan Fazli

6

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12 September 2017

Anne Warren

7

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Helen Scott

8

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Naomi Sharma

10

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Helene Bon

11

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Vinny Zecchini

12

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12 September 2017

Donna-Michelle Smith

13

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Nik Mathews

15

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Michelle Osborne

16

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Stewart Macarthur

18

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Kevin M Brindle

21

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John Griffiths

22

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12 September 2017

Martin E Gleave

23

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12 September 2017

Paul S Rennie

24

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Ian G Mills

26

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language of work or name

English

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publication date

20 May 2011

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30

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13

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2719-2733

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describes a project that uses

12 September 2017

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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Hypothalamic CaMKK2 contributes to the regulation of energy balance

13 September 2017

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AMPK phosphorylation of raptor mediates a metabolic checkpoint

13 September 2017

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

13 September 2017

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Cell- and gene-specific regulation of primary target genes by the androgen receptor

13 September 2017

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A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth

13 September 2017

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Identification of novel androgen receptor target genes in prostate cancer

13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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Identification of novel androgen response genes in prostate cancer cells by coupling chromatin immunoprecipitation and genomic microarray analysis

13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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Identification and validation of novel androgen-regulated genes in prostate cancer

13 September 2017

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13 September 2017

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13 September 2017

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MEK5 overexpression is associated with metastatic prostate cancer, and stimulates proliferation, MMP-9 expression and invasion

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease

13 September 2017

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STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase

13 September 2017

1 reference

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P504S: a new molecular marker for the detection of prostate carcinoma

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

13 September 2017

1 reference

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In vivo amplification of the androgen receptor gene and progression of human prostate cancer

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

The value of prior knowledge in discovering motifs with MEME.

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

A consensus DNA-binding site for the androgen receptor

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

CaM kinase kinase beta-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Androgen receptor amplification is reflected in the transcriptional responses of Vertebral-Cancer of the Prostate cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Inactivation of AMPK alters gene expression and promotes growth of prostate cancer cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

In vivo knockdown of the androgen receptor results in growth inhibition and regression of well-established, castration-resistant prostate tumors.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Androgen receptor and invasion in prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

New androgen receptor genomic targets show an interaction with the ETS1 transcription factor.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Androgen receptor-mediated repression of novel target genes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Identification and functional analysis of consensus androgen response elements in human prostate cancer cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Identification of an androgen response element in intron 8 of the sterol regulatory element-binding protein cleavage-activating protein gene allowing direct regulation by the androgen receptor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

BASH: a tool for managing BeadArray spatial artefacts

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Androgen receptor down regulation by small interference RNA induces cell growth inhibition in androgen sensitive as well as in androgen independent prostate cancer cells.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Discovery of BMS-641988, a novel and potent inhibitor of androgen receptor signaling for the treatment of prostate cancer

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

The stable isotope-based dynamic metabolic profile of butyrate-induced HT29 cell differentiation

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Androgens stimulate lipogenic gene expression in prostate cancer cells by activation of the sterol regulatory element-binding protein cleavage activating protein/sterol regulatory element-binding protein pathway

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Multiple G1 regulatory elements control the androgen-dependent proliferation of prostatic carcinoma cells.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression

21 August 2018

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Alpha-methylacyl coenzyme A racemase as a marker for prostate cancer

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21602788

12 December 2020

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Rat liver phosphofructokinase. Purification and characterization of its reaction mechanism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21602788

12 December 2020

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Zinc inhibition of mitochondrial aconitase and its importance in citrate metabolism of prostate epithelial cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21602788

12 December 2020

inferred from PubMed ID database lookup

Using galaxy to perform large-scale interactive data analyses

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.158

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/EMBOJ.2011.158

1 reference

12 September 2017

1 reference

12 September 2017

1 reference