Essential fatty acids enhance free radical generation and lipid peroxidation to induce apoptosis of tumor cells (Q56699406)

Requirement for generation of H2O2 for platelet-derived growth factor signal transduction

21 January 2018

1 reference

Regulation of reactive-oxygen-species generation in fibroblasts by Rac1.

21 January 2018

1 reference

Studies on lipid peroxidation in normal and tumour tissues. The Yoshida rat liver tumour

21 January 2018

1 reference

The acyl-CoA desaturases of microsomes from rat liver and the Morris 7777 hepatoma

21 January 2018

1 reference

The effect of chemical hepatocarcinogenesis on liver phospholipid composition in rats fed N-6 and N-3 fatty acid-supplemented diets

21 January 2018

1 reference

Essential Fatty acids - a review

21 January 2018

1 reference

Essential fatty acids: biochemistry, physiology and pathology

21 January 2018

1 reference

Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered epimers

21 January 2018

1 reference

Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals

21 January 2018

1 reference

Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing

21 January 2018

1 reference

Formation of endogenous "antiinflammatory" lipid mediators by transcellular biosynthesis. Lipoxins and aspirin-triggered lipoxins inhibit neutrophil recruitment and vascular permeability.

21 January 2018

1 reference

Elevated prostaglandin synthetase activity in methylcholanthrene-transformed mouse BALB/3T3

21 January 2018

1 reference

Elevated levels of prostaglandin E2 in Yoshida hepatoma and the inhibition of tumour growth by non-steroidal anti-inflammatory drugs

21 January 2018

1 reference

Elevated prostaglandin E2 production by monocytes is responsible for the depressed levels of natural killer and lymphokine-activated killer cell function in patients with breast cancer

21 January 2018

1 reference

Selected eicosanoids increase the proliferation rate of human colon carcinoma cell lines and mouse colonocytes in vivo.

21 January 2018

1 reference

Activities of free radical metabolizing enzymes in tumours

21 January 2018

1 reference

Lipid peroxidation and prostaglandins in colorectal cancer.

21 January 2018

1 reference

The mitochondrial theory of aging: insight from transgenic and knockout mouse models

21 January 2018

1 reference

Role of peroxide and superoxide anion during tumour cell apoptosis

21 January 2018

1 reference

Induction of necrotic-like cell death by tumor necrosis factor alpha and caspase inhibitors: novel mechanism for killing virus-infected cells

21 January 2018

1 reference

The use of transgenic and mutant mice to study oxygen free radical metabolism

21 January 2018

1 reference

Reactive oxygen species and mitochondria mediate the induction of apoptosis in human hepatoma HepG2 cells by the rodent peroxisome proliferator and hepatocarcinogen, perfluorooctanoic acid

21 January 2018

1 reference

Programmed cell death and Bcl-2 protection in very low oxygen.

21 January 2018

1 reference

Involvement of oxidative stress in tumor cytotoxic activity of hepatocyte growth factor/scatter factor

21 January 2018

1 reference

Growth factors prevent changes in Bcl-2 and Bax expression and neuronal apoptosis induced by nitric oxide

21 January 2018

1 reference

Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts

21 January 2018

1 reference

Reduced tumour necrosis factor-induced cytotoxicity by inhibitors of the arachidonic acid metabolism

21 January 2018

1 reference

Tumor necrosis factor is cytotoxic to human fibroblasts in the presence of exogenous arachidonic acid.

21 January 2018

1 reference

Cell killing and induction of manganous superoxide dismutase by tumor necrosis factor-alpha is mediated by lipoxygenase metabolites of arachidonic acid

21 January 2018

1 reference

The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor alpha activation of microglia and extends survival of G93A-SOD1 transgenic mice

21 January 2018

1 reference

The effects of TNF-alpha and inhibitors of arachidonic acid metabolism on human colon HT-29 cells depend on differentiation status

21 January 2018

1 reference

Induction of apoptosis by arachidonic acid in human retinoblastoma Y79 cells: involvement of oxidative stress.

21 January 2018

1 reference

Tumoricidal action of cis-unsaturated fatty acids and their relationship to free radicals and lipid peroxidation

21 January 2018

1 reference

Copper chelator enhancement of bleomycin cytotoxicity

21 January 2018

1 reference

Relationships between cellular superoxide dismutase and susceptibility to chemically induced cancer in the rat mammary gland

21 January 2018

1 reference

Stimulation of Mn-superoxide dismutase expression by tumor necrosis factor-alpha: quantitative determination of Mn-SOD protein levels in TNF-resistant and sensitive cells by ELISA.

21 January 2018

1 reference

The role of oxygen-derived free radicals in the cytotoxicity of doxorubicin in multidrug resistant and sensitive human ovarian cancer cells

21 January 2018

1 reference

Suppression of the malignant phenotype of human glioma cells by overexpression of manganese superoxide dismutase.

21 January 2018

1 reference

Expression of superoxide dismutases, catalase, and glutathione peroxidase in glioma cells

21 January 2018

1 reference

Decreased expression of manganese superoxide dismutase in transformed cells is associated with increased cytosine methylation of the SOD2 gene

21 January 2018

1 reference

Reactive oxygen intermediates regulate cellular response to apoptotic stimuli: an hypothesis

21 January 2018

1 reference

Reactive oxygen species mediate lysophosphatidic acid induced signaling in ovarian cancer cells.

21 January 2018

1 reference

Multi-mechanisms are involved in reactive oxygen species regulation of mTORC1 signaling

21 January 2018

1 reference

Fatty acid metabolism and cell proliferation. V. Evaluation of pathways for the generation of lipid peroxides

21 January 2018

1 reference

Fatty acid specificity in the inhibition of cell proliferation and its relationship to lipid peroxidation and prostaglandin biosynthesis

21 January 2018

1 reference

Regulation of cell division in a human glioma cell clone by arachidonic acid and alpha-tocopherolquinone.

21 January 2018

1 reference

Studies on the hyperplasia ('regeneration') of the rat liver following partial hepatectomy. Changes in lipid peroxidation and general biochemical aspects

21 January 2018

1 reference

P53, cell cycle control and apoptosis: Implications for cancer

21 January 2018

1 reference

Hydrogen peroxide induces nuclear translocation of p53 and apoptosis in cells of oligodendroglia origin

21 January 2018

1 reference

Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts.

21 January 2018

1 reference

Inactivation of Bcl-2 by phosphorylation

21 January 2018

1 reference

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

21 January 2018

1 reference

Essential fatty acids, lipid peroxidation and apoptosis

21 January 2018

1 reference

Bcl-2 and mitochondrial oxygen radicals. New approaches with reactive oxygen species-sensitive probes.

21 January 2018

1 reference

Combinatorial antileukemic disruption of oxidative homeostasis and mitochondrial stability by the redox reactive thalidomide 2-(2,4-difluoro-phenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione (CPS49) and flavopiridol.

21 January 2018

1 reference

Mechanisms of action of eicosapentaenoic acid in bladder cancer cells in vitro: alterations in mitochondrial metabolism, reactive oxygen species generation and apoptosis induction

21 January 2018

1 reference

Intratumoral gamma-linoleic acid therapy of human gliomas

21 January 2018

1 reference

Gamma-linolenic acid therapy of human gliomas

21 January 2018

1 reference

Intratumoural injection of gamma leinolenic acid in malignant gliomas.

21 January 2018

1 reference

Eicosanoid effects on cell proliferation in vitro: relevance to atherosclerosis

21 January 2018

1 reference

Intracellular unesterified arachidonic acid signals apoptosis

21 January 2018

1 reference

Effect of free fatty acids on two-stage skin carcinogenesis in mice.

21 January 2018

1 reference

n-3 polyunsaturated fatty acids and colon cancer prevention

21 January 2018

1 reference

n-3 PUFAs reduce VEGF expression in human colon cancer cells modulating the COX-2/PGE2 induced ERK-1 and -2 and HIF-1alpha induction pathway

21 January 2018

1 reference

Anti-angiogenesis effect of the novel anti-inflammatory and pro-resolving lipid mediators

21 January 2018

1 reference

Correlation Between Lipid Synthesis in Tumor Cells and Their Sensitivity to Humoral Immune Attack

21 January 2018

1 reference

Role of membrane lipids in the immunological killing of tumor cells: I. Target cell lipids.

21 January 2018

1 reference

Effects of N-6 essential fatty acids on glioma invasion and growth: experimental studies with glioma spheroids in collagen gels.

21 January 2018

1 reference

Highly unsaturated fatty acid induced tumour regression in glioma pharmacodynamics and bioavailability of gamma linolenic acid in an implantation glioma model: effects on tumour biomass, apoptosis and neuronal tissue histology

21 January 2018

1 reference

Gamma-linolenic acid alters Ku80, E2F1, and bax expression and induces micronucleus formation in C6 glioma cells in vitro

21 January 2018

1 reference

Effects of dietary polyunsaturated fatty acids on mitochondria

21 January 2018

1 reference

Long-term exposure of INS-1 rat insulinoma cells to linoleic acid and glucose in vitro affects cell viability and function through mitochondrial-mediated pathways

21 January 2018

1 reference

Protective effect of dietary n-3 polyunsaturated fatty acids on myocardial resistance to ischemia-reperfusion injury in rats

21 January 2018

1 reference

Complex I-associated hydrogen peroxide production is decreased and electron transport chain enzyme activities are altered in n-3 enriched fat-1 mice

21 January 2018

1 reference

Evaluation of the role of oxidative stress in chemopreventive action of fish oil and celecoxib in the initiation phase of 7,12-dimethyl benz(α)anthracene-induced mammary carcinogenesis.

21 January 2018

1 reference

The novel ruthenium-gamma-linolenic complex [Ru(2)(aGLA)(4)Cl] inhibits C6 rat glioma cell proliferation and induces changes in mitochondrial membrane potential, increased reactive oxygen species generation and apoptosis in vitro

21 January 2018

1 reference

Regulation of colorectal cancer cell apoptosis by the n-3 polyunsaturated fatty acids Docosahexaenoic and Eicosapentaenoic.

21 January 2018

1 reference

Effect of polyunsaturated fatty acids on diphenyl hydantoin-induced genetic damage in vitro and in vivo

21 January 2018

1 reference

Effect of gamma-linolenic acid and prostaglandins E1 on gamma-radiation and chemical-induced genetic damage to the bone marrow cells of mice

21 January 2018

1 reference

Tumoricidal and anti-angiogenic actions of gamma-linolenic acid and its derivatives

21 January 2018

1 reference

Pharmacological characterization of the cytoprotective effects of polyunsaturated fatty acids in insulin-secreting BRIN-BD11 cells

21 January 2018

1 reference

Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection

21 January 2018

1 reference

Long-chain polyunsaturated fatty acids and chemically induced diabetes mellitus: effect of omega-6 fatty acids

21 January 2018

1 reference

Long-chain polyunsaturated fatty acids and chemically induced diabetes mellitus. Effect of omega-3 fatty acids

21 January 2018

1 reference

Effect of n-6 and n-3 fatty acids on the survival of vincristine sensitive and resistant human cervical carcinoma cells in vitro.

21 January 2018

1 reference

Can tumour cell drug resistance be reversed by essential fatty acids and their metabolites?

21 January 2018

1 reference

Enhancement of doxorubicin cytotoxicity by polyunsaturated fatty acids in the human breast tumor cell line MDA-MB-231: relationship to lipid peroxidation.

21 January 2018

1 reference

Differential sensitization of cancer cells to doxorubicin by DHA: a role for lipoperoxidation.

21 January 2018

1 reference

Synergistic interaction between vinorelbine and gamma-linolenic acid in breast cancer cells

21 January 2018

1 reference

Gamma-linolenic acid modulates the response of multidrug-resistant K562 leukemic cells to anticancer drugs

21 January 2018

1 reference

Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells

21 January 2018

1 reference

Characterization of arachidonic acid-induced apoptosis

21 January 2018

1 reference

15-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells

21 January 2018

1 reference

Activation of different lipoxygenase isozymes induces apoptosis in human erythroleukemia and neuroblastoma cells

21 January 2018

1 reference

Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma

21 January 2018

1 reference

Inhibition of fatty acid synthase-dependent neoplastic lipogenesis as the mechanism of gamma-linolenic acid-induced toxicity to tumor cells: an extension to Nwankwo's hypothesis.

21 January 2018

1 reference

Why does tumor-associated fatty acid synthase (oncogenic antigen-519) ignore dietary fatty acids?

21 January 2018

1 reference

Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis

21 January 2018

1 reference

Proteasome inhibitors: their effects on arachidonic acid release from cells in culture and arachidonic acid metabolism in rat liver cells

21 January 2018

1 reference

Polyunsaturated fatty acids inhibit telomerase activity in DLD-1 human colorectal adenocarcinoma cells: a dual mechanism approach

21 January 2018

1 reference

Dual mechanisms for telomerase inhibition in DLD-1 human colorectal adenocarcinoma cells by polyunsaturated fatty acids.

21 January 2018

1 reference

Gamma linolenic acid regulates gap junction communication in endothelial cells and their interaction with tumour cells

21 January 2018

1 reference

Inhibition of phagocyte-endothelium interactions by oxidized fatty acids: a natural anti-inflammatory mechanism?

21 January 2018

1 reference

Ca2+ entry in T cells is activated by emptying the inositol 1,4,5-triphosphate sensitive Ca2+ pool

21 January 2018

1 reference

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

1 reference

N-6 and n-3 polyunsaturated fatty acids stimulate translocation of protein kinase Calpha, -betaI, -betaII and -epsilon and enhance agonist-induced NADPH oxidase in macrophages

21 January 2018

1 reference

Polyunsaturated fatty acids stimulate superoxide formation in tumor cells: a mechanism for specific cytotoxicity and a model for tumor necrosis factor?

21 January 2018

1 reference

Docosahexaenoic acid, a major constituent of fish oil diets, prevents activation of cyclin-dependent kinases and S-phase entry by serum stimulation in HT-29 cells

21 January 2018

1 reference

G alpha(i) and G alpha(o) are target proteins of reactive oxygen species

21 January 2018

1 reference

Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid

21 January 2018

1 reference

Occlusion of infusion vessels on gamma-linolenic acid infusion

21 January 2018

1 reference

Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model

21 January 2018

1 reference

A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease

21 January 2018

1 reference

Effect of ω-3 and ω-9 fatty acid rich oils on lipoxygenases and cyclooxygenases enzymes and on the growth of a mammary adenocarcinoma model

21 January 2018

1 reference

12(S)-HETE enhancement of prostate tumor cell invasion: selective role of PKC alpha

21 January 2018

1 reference

12-lipoxygenase metabolite 12(S)-HETE stimulates human pancreatic cancer cell proliferation via protein tyrosine phosphorylation and ERK activation

21 January 2018

1 reference

15‐hydroxy‐eicosatetraenoic acid arrests growth of colorectal cancer cells via a peroxisome proliferator‐activated receptor gamma‐dependent pathway

21 January 2018

1 reference

The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells

21 January 2018

1 reference

15-Lipoxygenase-1 has anti-tumorigenic effects in colorectal cancer

21 January 2018

1 reference

Lipoxin A4 and Its Analogue Suppress the Tumor Growth of Transplanted H22 in Mice: The Role of Antiangiogenesis

21 January 2018

1 reference

Docosahexaenoic acid metabolome in neural tumors: identification of cytotoxic intermediates.

21 January 2018

1 reference

Mechanisms and optimization of in vivo delivery of lipophilic siRNAs.

21 January 2018

1 reference

A novel method of modifying immune responses by vaccination with lipiodol-siRNA mixtures

21 January 2018

1 reference

Physico-chemical characteristics of lipoplexes influence cell uptake mechanisms and transfection efficacy

21 January 2018

1 reference

Lipid-like materials for low-dose, in vivo gene silencing

21 January 2018

1 reference

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

21 January 2018

1 reference

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

21 January 2018

1 reference

Modulation of intracellular second messengers by dietary fat during colonic tumor development

21 January 2018

1 reference

A radical approach to treatment

21 January 2018

1 reference

Superoxide dismutase as a target for the selective killing of cancer cells

21 January 2018

1 reference

The role of hydroxyl radical as a messenger in Cr(VI)-induced p53 activation

21 January 2018

1 reference

COCI

https://opencitations.net/index/coci/api/v1/citations/10.1152/AJPCELL.2000.279.3.C868

Hydrogen peroxide inhibits activation, not activity, of cellular caspase-3 in vivo

1 November 2021

1 reference

COCI