Hypoxia/reoxygenation-experienced cancer cell migration and metastasis are regulated by Rap1- and Rac1-GTPase activation via the expression of thymosin beta-4. (Q35833162)

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scientific article published in April 2015

Language	Label	Description	Also known as
English	Hypoxia/reoxygenation-experienced cancer cell migration and metastasis are regulated by Rap1- and Rac1-GTPase activation via the expression of thymosin beta-4.	scientific article published in April 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Hypoxia/reoxygenation-experienced cancer cell migration and metastasis are regulated by Rap1- and Rac1-GTPase activation via the expression of thymosin beta-4. (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

author name string

Jae-Wook Lee

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Yun-Kyoung Ryu

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Young-Hoon Ji

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Joo Hyun Kang

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Eun-Yi Moon

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

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publication date

1 April 2015

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

9820-9833

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Regulation of glycogen synthase kinase-3 by thymosin beta-4 is associated with gastric cancer cell migration

1 reference

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27 July 2018

Actin-sequestering protein, thymosin beta-4, is a novel hypoxia responsive regulator

1 reference

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27 July 2018

Actin-sequestering protein, thymosin beta-4, induces paclitaxel resistance through ROS/HIF-1alpha stabilization in HeLa human cervical tumor cells

1 reference

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Activation of Rap1 promotes prostate cancer metastasis

1 reference

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Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response

1 reference

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Sequential activation of Rap1 and Rac1 small G proteins by PDGF locally at leading edges of NIH3T3 cells.

1 reference

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Hypoxia-inducible transcription factor (HIF)-1 alpha stabilization by actin-sequestering protein, thymosin beta-4 (TB4) in Hela cervical tumor cells

1 reference

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Metastatic cancer cell

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ERK activation by thymosin-beta-4 (TB4) overexpression induces paclitaxel-resistance

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beta 1 integrin function in vivo: adhesion, migration and more

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Regulation of cancer cell motility through actin reorganization

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Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors

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Rap1 and SPA-1 in hematologic malignancy

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Activation of Rac1 by paxillin-Crk-DOCK180 signaling complex is antagonized by Rap1 in migrating NBT-II cells

1 reference

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27 July 2018

Overexpression of the thymosin beta-4 gene is associated with increased invasion of SW480 colon carcinoma cells and the distant metastasis of human colorectal carcinoma

1 reference

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27 July 2018

The beta-thymosin/WH2 domain; structural basis for the switch from inhibition to promotion of actin assembly

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Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

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27 July 2018

Cofilin promotes actin polymerization and defines the direction of cell motility

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Tyrosine Kinase p56 Regulates Cell Motility and Nuclear Factor κB-mediated Secretion of Urokinase Type Plasminogen Activator through Tyrosine Phosphorylation of IκBα following Hypoxia/Reoxygenation

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Targeting RAS signalling pathways in cancer therapy

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27 July 2018

Hypoxia--a key regulatory factor in tumour growth

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496400

27 July 2018

Rap1 signalling: adhering to new models

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496400

27 July 2018

beta-Thymosins, small acidic peptides with multiple functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496400

27 July 2018

Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

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27 July 2018

Small GTP-binding proteins

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Regulating actin-filament dynamics in vivo

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The hypoxic cell: a target for selective cancer therapy--eighteenth Bruce F. Cain Memorial Award lecture.

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Rapid Ca2+-mediated activation of Rap1 in human platelets

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Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap

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The directed migration of eukaryotic cells

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Thymosin beta 4 and Fx, an actin-sequestering peptide, are indistinguishable

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Overexpression of the thymosin beta-4 gene is associated with malignant progression of SW480 colon cancer cells

1 reference

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Rac1, RhoA, and Cdc42 participate in HeLa cell invasion by group B streptococcus

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Chemical characterization of thymosin beta 4

1 reference

https://pubmed.ncbi.nlm.nih.gov/25888632

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymosin beta4: a new molecular target for antitumor strategies

1 reference

https://pubmed.ncbi.nlm.nih.gov/25888632

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/ONCOTARGET.3218

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

0 references

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