Activation of Rac1 by paxillin-Crk-DOCK180 signaling complex is antagonized by Rap1 in migrating NBT-II cells (Q40525953)

21 September 2017

Activation of Rac1 by paxillin-Crk-DOCK180 signaling complex is antagonized by Rap1 in migrating NBT-II cells (English)

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21 September 2017

Ana M Vallés

1

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21 September 2017

Maud Beuvin

series ordinal

2

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21 September 2017

Brigitte Boyer

series ordinal

3

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21 September 2017

language of work or name

English

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publication date

12 August 2004

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Journal of Biological Chemistry

21 September 2017

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21 September 2017

279

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21 September 2017

43

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21 September 2017

44490-44496

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Assembly of Cell Regulatory Systems Through Protein Interaction Domains

21 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M405144200

Paxillin and focal adhesion signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M405144200

A fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migration

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M405144200

Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M405144200

Crk family adaptors-signalling complex formation and biological roles

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M405144200

Interaction between the amino-terminal SH3 domain of CRK and its natural target proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M405144200

Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

The adapter protein Crkl links Cbl to C3G after integrin ligation and enhances cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

The guanine nucleotide exchange factor C3G is necessary for the formation of focal adhesions and vascular maturation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M405144200

Rap1 signalling: adhering to new models

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M405144200

Cellular functions of the Rap1 GTP-binding protein: a pattern emerges

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M405144200

Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M405144200

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Activity of Rap1 is regulated by bombesin, cell adhesion, and cell density in NIH3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Rapid Ca2+-mediated activation of Rap1 in human platelets

21 January 2018

1 reference

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Ras and Rho GTPases: a family reunion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Rho GTPases in cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Dbl family guanine nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Laminin-10/11 and fibronectin differentially regulate integrin-dependent Rho and Rac activation via p130(Cas)-CrkII-DOCK180 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Tyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Integrins regulate Rac targeting by internalization of membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Localized Rac activation dynamics visualized in living cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M405144200

Membrane recruitment of DOCK180 by binding to PtdIns(3,4,5)P3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Cell migration: integrating signals from front to back

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Localized suppression of RhoA activity by Tyr31/118-phosphorylated paxillin in cell adhesion and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Cell-cell adhesion and signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Role of Rho family GTPases in epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Rap1 GTPase regulation of adherens junction positioning and cell adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405144200

21 January 2018

Identifiers

DOI

10.1074/JBC.M405144200

1 reference

21 September 2017

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