Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene (Q35599430)

9 August 2017

title

Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene (English)

1 reference

9 August 2017

0 references

1 reference

Hongyu Ying

1

1 reference

9 August 2017

Sanja Turturro

2

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9 August 2017

Tara Nguyen

3

1 reference

9 August 2017

Xiang Shen

4

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9 August 2017

Ruth Zelkha

5

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9 August 2017

Elaine C Johnson

6

1 reference

9 August 2017

John C Morrison

7

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9 August 2017

Beatrice Y J T Yue

8

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9 August 2017

publication date

6 May 2015

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9 August 2017

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9 August 2017

volume

16

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9 August 2017

page(s)

14

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Creative Commons Attribution 4.0 International

9 August 2017

copyright license

start time

6 May 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/s12860-015-0060-x

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cites work

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Activation of autophagy induces retinal ganglion cell death in a chronic hypertensive glaucoma model

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Overexpressed mutant optineurin(E50K) induces retinal ganglion cells apoptosis via the mitochondrial pathway

27 July 2018

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Cellular and molecular biology of optineurin

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Current understanding of conventional outflow dysfunction in glaucoma

27 July 2018

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Optineurin is required for CYLD-dependent inhibition of TNFα-induced NF-κB activation

27 July 2018

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Processing of optineurin in neuronal cells

27 July 2018

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Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429416

Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infection

27 July 2018

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Methods in mammalian autophagy research

27 July 2018

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Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant

27 July 2018

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Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth

27 July 2018

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Individual molecular response to elevated intraocular pressure in perfused postmortem human eyes

27 July 2018

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NF-kappaB mediates tumor necrosis factor alpha-induced expression of optineurin, a negative regulator of NF-kappaB.

27 July 2018

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The genetics of primary open-angle glaucoma: a review

27 July 2018

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Rat models for glaucoma research

27 July 2018

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SIRT1 activation confers neuroprotection in experimental optic neuritis

27 July 2018

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Studies of optineurin, a glaucoma gene: Golgi fragmentation and cell death from overexpression of wild-type and mutant optineurin in two ocular cell types

27 July 2018

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Light-driven cone arrestin translocation in cones of postnatal guanylate cyclase-1 knockout mouse retina treated with AAV-GC1.

27 July 2018

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Elevated intraocular pressure and optic nerve injury models in the rat.

27 July 2018

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Understanding mechanisms of pressure-induced optic nerve damage

27 July 2018

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Molecular cloning, genomic structure, and protein characterization of mouse optineurin

27 July 2018

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Gene therapy for optic nerve disease

27 July 2018

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

27 July 2018

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Optineurin in primary open angle glaucoma

27 July 2018

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Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model.

27 July 2018

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Expression of optineurin, a glaucoma-linked gene, is influenced by elevated intraocular pressure

27 July 2018

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Adult-onset primary open-angle glaucoma caused by mutations in optineurin

27 July 2018

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FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis

27 July 2018

1 reference

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Phorbol esters and cytokines regulate the expression of the NEMO-related protein, a molecule involved in a NF-kappa B-independent pathway

27 July 2018

1 reference

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Growing knowledge of the mTOR signaling network

27 July 2018

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Effects of mutations and deletions in the human optineurin gene.

26 September 2018

1 reference

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Medicine. A common pathway for a rare disease?

26 September 2018

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26 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429416

Adeno-associated virus-mediated expression of growth-associated protein-43 aggravates retinal ganglion cell death in experimental chronic glaucomatous injury

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429416

Plk1-dependent phosphorylation of optineurin provides a negative feedback mechanism for mitotic progression

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429416

Differential involvement of optineurin in amyotrophic lateral sclerosis with or without SOD1 mutations

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429416

Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429416

Impairment of protein trafficking upon overexpression and mutation of optineurin

26 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429416

Functional and behavioral restoration of vision by gene therapy in the guanylate cyclase-1 (GC1) knockout mouse.

26 September 2018

1 reference

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Mutations of optineurin in amyotrophic lateral sclerosis

26 September 2018

1 reference

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Posttranslational modifications, localization, and protein interactions of optineurin, the product of a glaucoma gene

26 September 2018

1 reference

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Recharacterization of the RGC-5 retinal ganglion cell line

26 September 2018

1 reference

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Monitoring autophagic degradation of p62/SQSTM1.

26 September 2018

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Activation of autophagy in retinal ganglion cells

26 September 2018

1 reference

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Rab8-optineurin-myosin VI: analysis of interactions and functions in the secretory pathway

26 September 2018

1 reference

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Focus on molecules: optineurin

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429416

Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429416

Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

26 September 2018

1 reference

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Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells

26 September 2018

1 reference

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The mutant human ND4 subunit of complex I induces optic neuropathy in the mouse

26 September 2018

1 reference

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Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.

26 September 2018

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Distribution of optineurin sequence variations in an ethnically diverse population of low-tension glaucoma patients from the United States

26 September 2018

1 reference

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The effect of experimental glaucoma and optic nerve transection on amacrine cells in the rat retina

26 September 2018

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Activation of the extracellular signal-regulated kinase 1/2 pathway by AAV gene transfer protects retinal ganglion cells in glaucoma

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429416

Activation of caspase 9 in a rat model of experimental glaucoma

26 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429416

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

26 September 2018

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Gene delivery to the eye using adeno-associated viral vectors

26 September 2018

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Intravitreal injection of adeno-associated viral vectors results in the transduction of different types of retinal neurons in neonatal and adult rats: a comparison with lentiviral vectors.

26 September 2018

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Baculoviral IAP repeat-containing-4 protects optic nerve axons in a rat glaucoma model

26 September 2018

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Mammalian target of rapamycin (mTOR): pro- and anti-apoptotic

26 September 2018

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Effects of donor age on proteasome activity and senescence in trabecular meshwork cells

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12860-015-0060-X

The majority of the genetic risk for Paget’s disease of bone is explained by genetic variants close to the CSF1, OPTN, TM7SF4, and TNFRSF11A genes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12860-015-0060-X

A rat model of chronic pressure-induced optic nerve damage

21 January 2018

1 reference

12 December 2020

Overexpression of proteasome beta5 assembled subunit increases the amount of proteasome and confers ameliorated response to oxidative stress and higher survival rates

1 reference

12 December 2020

Optineurin: a new vision of cell division control

1 reference

12 December 2020

The cell and molecular biology of complex forms of glaucoma: updates on genetic, environmental, and epigenetic risk factors

1 reference

12 December 2020

1 reference

12 December 2020

Clinical features and course of patients with glaucoma with the E50K mutation in the optineurin gene

1 reference

12 December 2020

10.1186/S12860-015-0060-X

Identifiers

DOI

1 reference

Dimensions Publication ID

9 August 2017

1026731084

0 references

Fatcat ID

release_amjlyfqxwrgdpb66t7kyaamu7q

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/amjlyfqxwrgdpb66t7kyaamu7q

24 November 2022

mapped directly with Wikidata item

PMC publication ID

4429416

1 reference

9 August 2017

1 reference