Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP (Q24337587)

positive regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

Receptor (TNFRSF)-interacting serine-threonine kinase 1

1 reference

Tumor necrosis factor receptor superfamily, member 1a

1 reference

Inhibitor of kappaB kinase gamma

1 reference

Optineurin

1 reference

Lack of association of mutations in optineurin with disease in patients with adult-onset primary open-angle glaucoma

protein ubiquitination

1 reference

Guozhi Zhu

1

0 references

Chuan-Jin Wu

series ordinal

2

0 references

Yongge Zhao

series ordinal

3

0 references

Jonathan D Ashwell

series ordinal

4

0 references

language of work or name

English

0 references

publication date

21 August 2007

0 references

published in

Current Biology

0 references

volume

17

0 references

page(s)

1438-43

0 references

issue

16

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Tumor necrosis factor-alpha: a potentially neurodestructive cytokine produced by glia in the human glaucomatous optic nerve head

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Essential role for IKKgamma/NEMO in TCR-induced IL-2 expression in Jurkat T cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Tumor necrosis factor alpha increases neuronal vulnerability to excitotoxic necrosis by inducing expression of the AMPA-glutamate receptor subunit GluR1 via an acid sphingomyelinase- and NF-kappaB-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

TNF alpha potentiates glutamate neurotoxicity by inhibiting glutamate uptake in organotypic brain slice cultures: neuroprotection by NF kappa B inhibition

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Association of glaucoma with neurodegenerative diseases with apoptotic cell death: Alzheimer's disease and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Evaluation of optineurin sequence variations in 1,048 patients with open-angle glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

IFNalpha sensitizes ME-180 human cervical cancer cells to TNFalpha-induced apoptosis by inhibiting cytoprotective NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

In glaucoma, should enthusiasm about neuroprotection be tempered by the experience obtained in other neurodegenerative disorders?

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Nuclear factor-kappaB in cancer development and progression

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Inhibition of transcription factor NF-κB in the central nervous system ameliorates autoimmune encephalomyelitis in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Interferon-alpha sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-kappa B inactivation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Tumor necrosis factor induces lipopolysaccharide tolerance in a human adenocarcinoma cell line mainly through the TNF p55 receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Phorbol esters and cytokines regulate the expression of the NEMO-related protein, a molecule involved in a NF-kappa B-independent pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Interferon gamma (IFNgamma ) and tumor necrosis factor alpha synergism in ME-180 cervical cancer cell apoptosis and necrosis. IFNgamma inhibits cytoprotective NF-kappa B through STAT1/IRF-1 pathways

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Huntingtin interacts with a family of WW domain proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Identification of a transcription factor IIIA-interacting protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Lessons for glaucoma from other neurodegenerative diseases: can one treatment suit them all?

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Adult-onset primary open-angle glaucoma caused by mutations in optineurin

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Interaction of an adenovirus E3 14.7-kilodalton protein with a novel tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

B-cell receptor- and phorbol ester-induced NF-kappaB and c-Jun N-terminal kinase activation in B cells requires novel protein kinase C's

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

The carboxyl-terminal region of IkappaB kinase gamma (IKKgamma) is required for full IKK activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Prevalence of optineurin sequence variants in adult primary open angle glaucoma: implications for diagnostic testing

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

Clinical features and course of patients with glaucoma with the E50K mutation in the optineurin gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021

IFN-alpha suppresses activation of nuclear transcription factors NF-kappa B and activator protein 1 and potentiates TNF-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2007.07.041

7 January 2021