Resistance to cytotoxic and anti-angiogenic anticancer agents: similarities and differences (Q35177652)

6 August 2017

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title

Resistance to cytotoxic and anti-angiogenic anticancer agents: similarities and differences (English)

1 reference

6 August 2017

angiogenesis inhibitor

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Henk J Broxterman

1

1 reference

PubMed ID

12860459

6 August 2017

Jan Lankelma

series ordinal

2

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PubMed ID

12860459

6 August 2017

Klaas Hoekman

series ordinal

3

1 reference

6 August 2017

1 June 2003

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6 August 2017

Drug Resistance Updates

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6 August 2017

6

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6 August 2017

3

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6 August 2017

111-127

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The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit.

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Intraperitoneal therapy for stage III ovarian cancer: a therapy whose time has come!

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Standard versus intensified chemotherapy with granulocyte colony-stimulating factor support in small-cell lung cancer: a prospective European Organization for Research and Treatment of Cancer-Lung Cancer Group Phase III Trial-08923.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Determinants of drug delivery and transport to solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Apoptosis: coming to terms with biological diversity

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

p53 inhibits hypoxia-inducible factor-stimulated transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Does resistance to apoptosis affect clinical response to antitumor drugs?

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Apoptosis: mediator or mode of cell killing by anticancer agents?

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Cancer research 2001: drug resistance, new targets and drug combinations.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Direct activation of caspases by RGD-peptides may increase drug sensitivity of tumour cells

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Correlation between functional and molecular analysis of mdr1 P-glycoprotein in human solid-tumor xenografts

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Theoretical and practical considerations for the measurement of P-glycoprotein function in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

P-glycoprotein in primary acute myeloid leukemia and treatment outcome of idarubicin/cytosine arabinoside-based induction therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

What went wrong with Iressa?

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: possible involvement of the phosphoinositide-3 kinase/Akt pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Chemosensitization by fibroblast growth factor-2 is not dependent upon proliferation, S-phase accumulation, or p53 status

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Localisation of breast cancer resistance protein in microvessel endothelium of human brain

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

The tumor microenvironment as a determinant of drug response and resistance.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Comparison of anthracycline-induced death of human leukemia cells: programmed cell death versus necrosis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Synthesis and biological evaluation of novel prodrugs of anthracyclines for selective activation by the tumor-associated protease plasmin

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

A peptide-doxorubicin 'prodrug' activated by prostate-specific antigen selectively kills prostate tumor cells positive for prostate-specific antigen in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Multicellular resistance: a paradigm for clinical resistance?

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

High-dose chemotherapy in breast cancer: where are we now?

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Overexpression of the 18 kDa and 22/24 kDa FGF-2 isoforms results in differential drug resistance and amplification potential.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Characterization of a novel prostate-specific antigen-activated peptide-doxorubicin conjugate in patients with prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Inhibition of tumor angiogenesis by non-steroidal anti-inflammatory drugs: emerging mechanisms and therapeutic perspectives

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Slow penetration of anthracyclines into spheroids and tumors: a therapeutic advantage?

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Role of mitogen-activated protein kinases in the response of tumor cells to chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Determining MDR1/P-glycoprotein expression in breast cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

The role of pro-drug therapy in the treatment of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

p53 as a therapeutic target: unresolved issues on the road to cancer therapy targeting mutant p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Reconstituted basement membrane (matrigel) and laminin can enhance the tumorigenicity and the drug resistance of small cell lung cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

1 reference

7 January 2021

In vivo veritas: Bcl-2 and Bcl-X(L)mediate tumor cell resistance to chemotherapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

CD44 signaling through focal adhesion kinase and its anti-apoptotic effect

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Could less be more? Low-dose chemotherapy goes on trial

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

MDR1 inhibition: less resistance or less relevance?

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Tumor vessel development and maturation impose limits on the effectiveness of anti-vascular therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Clinical cancer research 2002: new agents and therapies

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Mathematical models of drug resistance and chemotherapy effects.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Mitochondria as targets for established and novel anti-cancer agents

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Rapid acquisition of multicellular drug resistance after a single exposure of mammary tumor cells to antitumor alkylating agents.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Comparison of antiangiogenic activities using paclitaxel (taxol) and docetaxel (taxotere).

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

CD95(Fas/APO-1) signals ceramide generation independent of the effector stage of apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Adhesion to fibronectin via beta1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR).

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Potential and caveats of TRAIL in cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Paclitaxel/carboplatin administration along with antiangiogenic therapy in non-small-cell lung and breast carcinoma models

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Safety and pharmacokinetic effects of TNP-470, an angiogenesis inhibitor, combined with paclitaxel in patients with solid tumors: evidence for activity in non-small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Caspase-dependent initiation of apoptosis and necrosis by the Fas receptor in lymphoid cells: onset of necrosis is associated with delayed ceramide increase

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

A novel doxorubicin-glucuronide prodrug DOX-GA3 for tumour-selective chemotherapy: distribution and efficacy in experimental human ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Vascular endothelial growth factor immunoneutralization plus Paclitaxel markedly reduces tumor burden and ascites in athymic mouse model of ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

A reevaluation of integrins as regulators of angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Tumor angiogenesis and accessibility: role of vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Chemosensitisation of malignant melanoma by BCL2 antisense therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Effects of combination anti-vascular endothelial growth factor receptor and anti-epidermal growth factor receptor therapies on the growth of gastric cancer in a nude mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Inhibition of tumor angiogenesis as a strategy to circumvent acquired resistance to anti-cancer therapeutic agents

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Clinical translation of angiogenesis inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

In vitro chemosensitivity testing using the multicellular tumor spheroid model.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Inhibition of endothelial cell survival and angiogenesis by protein kinase A

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Computational systems biology

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Apoptotic markers for tumor recurrence: a minireview

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

In vitro chemo- and radio-resistance in small cell lung cancer correlates with cell adhesion and constitutive activation of AKT and MAP kinase pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Mechanisms of resistance to imatinib (STI571) and prospects for combination with conventional chemotherapeutic agents

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SU5416 in patients with solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Tissue transport of anti-cancer drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Paclitaxel (Taxol): an inhibitor of angiogenesis in a highly vascularized transgenic breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Signaling pathways activated by daunorubicin

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Paclitaxel (Taxol)-induced gene expression and cell death are both mediated by the activation of c-Jun NH2-terminal kinase (JNK/SAPK)

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Clinical use of TNF revisited: improving penetration of anti-cancer agents by increasing vascular permeability

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Integrins regulate the apoptotic response to DNA damage through modulation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Effect of local anti-VEGF antibody treatment on tumor microvessel permeability

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: a Southwest Oncology Group study

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Multiple mutations and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Anthracycline drug targeting: cytoplasmic versus nuclear--a fork in the road

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Tumstatin, an endothelial cell-specific inhibitor of protein synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Liposomal formulations of anticancer drugs: selectivity and effectiveness

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

A signaling pathway from the alpha5beta1 and alpha(v)beta3 integrins that elevates bcl-2 transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Redefining the target: chemotherapeutics as antiangiogenics

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

New advances on structural and biological functions of ceramide in apoptotic/necrotic cell death and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Anti-angiogenesis therapy:concepts and importance of dosing schedules in clinical trials

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Control of apoptosis during angiogenesis by survivin expression in endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Updates on functions of ceramide in chemotherapy-induced cell death and in multidrug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Role of ceramide in mediating the inhibition of telomerase activity in A549 human lung adenocarcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Targeting tumor cell resistance to apoptosis induction with antisense oligonucleotides: progress and therapeutic potential

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Retinoids in combination therapies for the treatment of cancer: mechanisms and perspectives

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Involvement of platelet-derived growth factor in disease: development of specific antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Activation of Bak, Bax, and BH3-only proteins in the apoptotic response to doxorubicin.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Fibroblast growth factor-2 induces translational regulation of Bcl-XL and Bcl-2 via a MEK-dependent pathway: correlation with resistance to etoposide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

High-dose chemotherapy: how resistant is breast cancer?

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Tumor senescence as a determinant of drug response in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Evidence for the involvement of endothelial cell integrin alphaVbeta3 in the disruption of the tumor vasculature induced by TNF and IFN-gamma

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Future perspectives for the development of P-glycoprotein modulators

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Mechanisms and future directions for angiogenesis-based cancer therapies

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

EGF receptor targeting in therapy-resistant human tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Apoptosis is critical for drug response in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Small cell and its stroma: determinant of pan-resistance?

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Re: Rapid acquisition of multicellular drug resistance after a single exposure of mammary tumor cells to antitumor alkylating agents.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Downmodulation of bFGF-binding protein expression following restoration of p53 function

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Hyaluronidase reduces human breast cancer xenografts in SCID mice

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Apoptosis: a guide for the perplexed.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Fibroblast growth factors: an epigenetic mechanism of broad spectrum resistance to anticancer drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Reversal of intrinsic and acquired forms of drug resistance by hyaluronidase treatment of solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

An added dimension: will three-dimensional cultures improve our understanding of drug resistance?

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Get a ligand, get a life: integrins, signaling and cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Resistance to adriamycin in multicellular spheroids

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Breast cancer response to paclitaxel in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Epigenetic determinants of resistance to etoposide regulation of Bcl-X(L) and Bax by tumor microenvironmental factors

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Role of angiogenesis in the response to anticancer therapies

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Tumor resistance to alkylating agents conferred by mechanisms operative only in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Effect of cell-cell interactions on drug sensitivity and growth of drug-sensitive and -resistant tumor cells in spheroids.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

A role for survivin in chemoresistance of endothelial cells mediated by VEGF

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Functional characterization of minimal residual disease for P-glycoprotein and multidrug resistance protein activity in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

TNF-alpha augments intratumoural concentrations of doxorubicin in TNF-alpha-based isolated limb perfusion in rat sarcoma models and enhances anti-tumour effects

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

A doxorubicin-CNGRC-peptide conjugate with prodrug properties

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Differentiation dependent expression of P-glycoprotein in the normal and neoplastic human kidney

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Clinical cancer research 2001: new agents and therapies.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Mechanisms of resistance imatinib (STI571) in preclinical models and in leukemia patients

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Activation of the PI3K/Akt pathway and chemotherapeutic resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

In vitro transepithelial drug transport by on-line measurement: cellular control of paracellular and transcellular transport

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Effect of p53 status on tumor response to antiangiogenic therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Survivin expression and resistance to anticancer treatments: perspectives for new therapeutic interventions.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2803%2900026-8

7 January 2021

10.1016/S1368-7646(03)00026-8

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12860459