Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ (Q44129457)

30 November 2017

Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ (English)

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30 November 2017

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5

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30 November 2017

4

Gregory J Gores

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30 November 2017

Christina R Arnt

1

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30 November 2017

Mihnea V Chiorean

series ordinal

2

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30 November 2017

Michael P Heldebrant

series ordinal

3

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30 November 2017

language of work or name

English

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publication date

5 September 2002

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Journal of Biological Chemistry

30 November 2017

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30 November 2017

277

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30 November 2017

44236-44243

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30 November 2017

46

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Cell death: the significance of apoptosis

30 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.M207578200

Caspases: the executioners of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Caspases: intracellular signaling by proteolysis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M207578200

Proteolytic activities that mediate apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

An exegesis of IAPs: salvation and surprises from BIR motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

IAP proteins: blocking the road to death's door

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M207578200

IAP family proteins--suppressors of apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M207578200

RING finger proteins: mediators of ubiquitin ligase activity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M207578200

X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M207578200

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M207578200

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M207578200

Structural basis of caspase-7 inhibition by XIAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Structural basis for the inhibition of caspase-3 by XIAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Apoptosis. Baiting death inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Biochemical and genetic interactions between Drosophila caspases and the proapoptotic genes rpr, hid, and grim

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Molecular mechanisms of cell death and phagocytosis in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

The damage-responsive Drosophila gene sickle encodes a novel IAP binding protein similar to but distinct from reaper, grim, and hid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Drosophila sickle is a novel grim-reaper cell death activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Sequence requirements for Hid binding and apoptosis regulation in the baculovirus inhibitor of apoptosis Op-IAP. Hid binds Op-IAP in a manner similar to Smac binding of XIAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Resistance to diverse apoptotic triggers in multidrug resistant HL60 cells and its possible relationship to the expression of P-glycoprotein, Fas and of the novel anti-apoptosis factors IAP (inhibitory of apoptosis proteins).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Lack of correlation between caspase activation and caspase activity assays in paclitaxel-treated MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

In vivo protein transduction: delivery of a biologically active protein into the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Comparison of paclitaxel-, 5-fluoro-2'-deoxyuridine-, and epidermal growth factor (EGF)-induced apoptosis. Evidence for EGF-induced anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Measurement of protein using bicinchoninic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Getting hydrophilic compounds into cells: lessons from homeopeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Trojan peptides: the penetratin system for intracellular delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

The antennapedia peptide penetratin translocates across lipid bilayers - the first direct observation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Generation and characterization of Smac/DIABLO-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Commitment to cell death measured by loss of clonogenicity is separable from the appearance of apoptotic markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Molecular effects of paclitaxel: myths and reality (a critical review).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

Reutilization of Immunoblots after Chemiluminescent Detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207578200

21 January 2018

Identifiers

DOI

10.1074/JBC.M207578200

1 reference

30 November 2017

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