Identification of cis-acting elements and splicing factors involved in the regulation of BIM Pre-mRNA splicing (Q35151577)

6 August 2017

Identification of cis-acting elements and splicing factors involved in the regulation of BIM Pre-mRNA splicing (English)

1 reference

6 August 2017

2

1 reference

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31 May 2020

S T Ong

series ordinal

3

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31 May 2020

author name string

Wen Chun Juan

series ordinal

1

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31 May 2020

language of work or name

English

0 references

publication date

17 April 2014

1 reference

6 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24743263%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

9

1 reference

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31 May 2020

page(s)

e95210

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31 May 2020

issue

4

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Creative Commons Attribution 4.0 International

31 May 2020

copyright license

start time

17 April 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Regulation of splicing by SR proteins and SR protein-specific kinases

13 July 2018

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A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer

13 July 2018

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The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation

13 July 2018

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Genetic variation of pre-mRNA alternative splicing in human populations

13 July 2018

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Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas

13 July 2018

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13 July 2018

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Context-dependent splicing regulation: exon definition, co-occurring motif pairs and tissue specificity

13 July 2018

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miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes

13 July 2018

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RNA sequencing reveals the role of splicing polymorphisms in regulating human gene expression

13 July 2018

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iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution

13 July 2018

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SFmap: a web server for motif analysis and prediction of splicing factor binding sites

13 July 2018

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Expansion of the eukaryotic proteome by alternative splicing

13 July 2018

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Refining the minimal sequence required for ERK1/2-dependent poly-ubiquitination and proteasome-dependent turnover of BIM.

13 July 2018

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The pathobiology of splicing

13 July 2018

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13 July 2018

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Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics

13 July 2018

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Human Splicing Finder: an online bioinformatics tool to predict splicing signals

13 July 2018

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hnRNP H enhances skipping of a nonfunctional exon P3A in CHRNA1 and a mutation disrupting its binding causes congenital myasthenic syndrome

13 July 2018

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hnRNP H and hnRNP F complex with Fox2 to silence fibroblast growth factor receptor 2 exon IIIc

13 July 2018

1 reference

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Multisite phosphorylation regulates Bim stability and apoptotic activity

13 July 2018

1 reference

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The BCL-2 protein family: opposing activities that mediate cell death

13 July 2018

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Features of 5'-splice-site efficiency derived from disease-causing mutations and comparative genomics

13 July 2018

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Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations

13 July 2018

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Splicing in disease: disruption of the splicing code and the decoding machinery

13 July 2018

1 reference

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PTB/nPTB switch: a post-transcriptional mechanism for programming neuronal differentiation

13 July 2018

1 reference

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PLP/DM20 ratio is regulated by hnRNPH and F and a novel G-rich enhancer in oligodendrocytes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro

13 July 2018

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Activation of alpha-tropomyosin exon 2 is regulated by the SR protein 9G8 and heterogeneous nuclear ribonucleoproteins H and F.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.

13 July 2018

1 reference

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Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas

13 July 2018

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Comprehensive splice-site analysis using comparative genomics

13 July 2018

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UNR translation can be driven by an IRES element that is negatively regulated by polypyrimidine tract binding protein

13 July 2018

1 reference

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A combinatorial code for splicing silencing: UAGG and GGGG motifs

13 July 2018

1 reference

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Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Computational definition of sequence motifs governing constitutive exon splicing.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Mechanisms of alternative pre-messenger RNA splicing

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

RNAi-mediated PTB depletion leads to enhanced exon definition

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

The Bcl2 family: regulators of the cellular life-or-death switch

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

SR proteins and hnRNP H regulate the splicing of the HIV-1 tev-specific exon 6D.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Exon Identity Established through Differential Antagonism between Exonic Splicing Silencer-Bound hnRNP A1 and Enhancer-Bound SR Proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Protein factor requirements of the Apaf-1 internal ribosome entry segment: roles of polypyrimidine tract binding protein and upstream of N-ras

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

An intronic splicing silencer causes skipping of the IIIb exon of fibroblast growth factor receptor 2 through involvement of polypyrimidine tract binding protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Binding of hnRNP H to an exonic splicing silencer is involved in the regulation of alternative splicing of the rat beta-tropomyosin gene

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Bim: a novel member of the Bcl-2 family that promotes apoptosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

A naturally arising mutation of a potential silencer of exon splicing in human immunodeficiency virus type 1 induces dominant aberrant splicing and arrests virus production

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

The polypyrimidine tract binding protein binds upstream of neural cell-specific c-src exon N1 to repress the splicing of the intron downstream

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Selection of the bovine papillomavirus type 1 nucleotide 3225 3' splice site is regulated through an exonic splicing enhancer and its juxtaposed exonic splicing suppressor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Short artificial hairpins sequester splicing signals and inhibit yeast pre-mRNA splicing

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

The proapoptotic Bcl-2 family member Bim plays a central role during the development of virus-induced hepatitis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

SpliceAid: a database of experimental RNA target motifs bound by splicing proteins in humans.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Selective involvement of BH3-only Bcl-2 family members Bim and Bad in neonatal hypoxia-ischemia.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Low-level expression of proapoptotic Bcl-2-interacting mediator in leukemic cells in patients with chronic myeloid leukemia: role of BCR/ABL, characterization of underlying signaling pathways, and reexpression by novel pharmacologic compounds.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Allele-specific transcript isoforms in human

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

New type of disease causing mutations: the example of the composite exonic regulatory elements of splicing in CFTR exon 12.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990581

Polypyrimidine tract binding protein interacts with sequences involved in alternative splicing of beta-tropomyosin pre-mRNA

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24743263

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Heterogeneous nuclear ribonucleoprotein F/H proteins modulate the alternative splicing of the apoptotic mediator Bcl-x

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24743263

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Multiple triggers of cell death in sepsis: death receptor and mitochondrial-mediated apoptosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24743263

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0095210

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24743263%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

0 references

1 reference

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31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24743263%20AND%20SRC:MED&resulttype=core&format=json