Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic. (Q35075545)

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30 December 2019

title

Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic (English)

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30 December 2019

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corrigendum / erratum

Correction for Kuroda et al., Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic

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author

Hamsa Puthalakath

2

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30 December 2019

Mark S Cragg

3

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30 December 2019

Philippe Bouillet

5

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30 December 2019

David C Huang

6

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30 December 2019

Oliver Ottmann

8

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30 December 2019

Brian Druker

9

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30 December 2019

Andrew W. Roberts

11

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30 December 2019

Andreas Strasser

12

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30 December 2019

1

Junya Kuroda

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30 December 2019

4

Priscilla N Kelly

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30 December 2019

author name string

Shinya Kimura

7

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30 December 2019

Andreas Villunger

10

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30 December 2019

language of work or name

English

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publication date

22 September 2006

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Proceedings of the National Academy of Sciences of the United States of America

30 December 2019

published in

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30 December 2019

volume

103

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30 December 2019

page(s)

14907-14912

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30 December 2019

issue

40

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours

30 December 2019

cites work

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Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

8 July 2018

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8 July 2018

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8 July 2018

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Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors

8 July 2018

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Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim.

8 July 2018

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Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

8 July 2018

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Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

8 July 2018

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p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

8 July 2018

1 reference

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Bad-deficient mice develop diffuse large B cell lymphoma

8 July 2018

1 reference

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The third-generation bisphosphonate zoledronate synergistically augments the anti-Ph+ leukemia activity of imatinib mesylate

8 July 2018

1 reference

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Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

8 July 2018

1 reference

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A member of Forkhead transcription factor FKHRL1 is a downstream effector of STI571-induced cell cycle arrest in BCR-ABL-expressing cells

8 July 2018

1 reference

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Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

8 July 2018

1 reference

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Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

8 July 2018

1 reference

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BH3-Only proteins-essential initiators of apoptotic cell death

8 July 2018

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8 July 2018

1 reference

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Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL

8 July 2018

1 reference

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Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival

8 July 2018

1 reference

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Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L)

8 July 2018

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

8 July 2018

1 reference

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

8 July 2018

1 reference

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Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in Epstein-Barr virus (EBV)-related lymphoma cell lines.

8 July 2018

1 reference

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Overexpression of P-glycoprotein in K562 cells does not confer resistance to the growth inhibitory effects of imatinib (STI571) in vitro

8 July 2018

1 reference

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Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment

27 September 2018

1 reference

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27 September 2018

Identifiers

DOI

10.1073/PNAS.0606176103

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30 December 2019

0 references

1 reference

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30 December 2019

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