Cellular senescence and organismal ageing in the absence of p21(CIP1/WAF1) in ku80(-/-) mice (Q34903039)

5 August 2017

title

Cellular senescence and organismal ageing in the absence of p21(CIP1/WAF1) in ku80(-/-) mice (English)

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5 August 2017

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Bo Zhao

1

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5 August 2017

Erica K Benson

2

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5 August 2017

Ruifang Qiao

3

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5 August 2017

Xing Wang

4

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5 August 2017

Sunchin Kim

5

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5 August 2017

James J Manfredi

6

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5 August 2017

Sam W Lee

7

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5 August 2017

Stuart A Aaronson

8

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5 August 2017

publication date

12 December 2008

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5 August 2017

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5 August 2017

volume

10

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5 August 2017

issue

1

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5 August 2017

page(s)

71-78

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Deletion of Ku80 causes early aging independent of chronic inflammation and Rag-1-induced DSBs

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

DNA damage-induced cellular senescence is sufficient to suppress tumorigenesis: a mouse model

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Lamin A-dependent nuclear defects in human aging

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Aging and genome maintenance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

The mechanism of vertebrate nonhomologous DNA end joining and its role in V(D)J recombination

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Cooperative effects of genes controlling the G(2)/M checkpoint

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Analysis of ku80-mutant mice and cells with deficient levels of p53

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Deletion of Ku86 causes early onset of senescence in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

The gene responsible for Werner syndrome may be a cell division "counting" gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Radiation-induced cell cycle arrest compromised by p21 deficiency

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Ku80 and p53 suppress medulloblastoma that arise independent of Rag-1-induced DSBs.

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOR.2008.220

Tumor surveillance via the ARF-p53 pathway.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOR.2008.220

DNA ligase IV suppresses medulloblastoma formation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Tumor susceptibility of p21(Waf1/Cip1)-deficient mice.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613205

Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts

26 October 2018

1 reference

12 December 2020

p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53

1 reference

12 December 2020

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation

1 reference

12 December 2020

Hematopoietic stem cell quiescence maintained by p21cip1/waf1

1 reference

12 December 2020

Identifiers

DOI

10.1038/EMBOR.2008.220

1 reference

5 August 2017

1 reference

5 August 2017

1 reference