UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer (Q33955751)

30 July 2017

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title

UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer (English)

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30 July 2017

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de Gruijl FR

1

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PubMed ID

11684448

30 July 2017

van Kranen HJ

series ordinal

2

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PubMed ID

11684448

30 July 2017

Mullenders LH

series ordinal

3

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30 July 2017

1 October 2001

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Journal of Photochemistry and Photobiology B

30 July 2017

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30 July 2017

63

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30 July 2017

19-27

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30 July 2017

1-3

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30 July 2017

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

DNA hypermethylation in tumorigenesis: epigenetics joins genetics

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Nonmelanoma skin cancer in the United States: incidence.

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Does intermittent sun exposure cause basal cell carcinoma? a case-control study in Western Australia

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA.

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC.

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Proofreading of DNA polymerase eta-dependent replication errors

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Polymerase eta deficiency in the xeroderma pigmentosum variant uncovers an overlap between the S phase checkpoint and double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Elevated UV-B radiation reduces genome stability in plants.

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

UV-induced mutation hotspots occur at DNA damage hotspots

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

The role of DNA polymerase in base substitution mutagenesis on non-instructional templates.

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Wavelength dependence of oxidative DNA damage induced by UV and visible light

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

A role for ultraviolet A in solar mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

The formation of mispairs by 8-oxyguanine as a pathway of mutations induced by irradiation and oxygen radicals

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

The induction and analysis of micronuclei and cell killing by ultraviolet-B radiation in human peripheral blood lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Low doses of UVB or UVA induce chromosomal aberrations in cultured human skin cells

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Frequent p53 alterations but low incidence of ras mutations in UV-B-induced skin tumors of hairless mice

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

The role of UV-B light in skin carcinogenesis through the analysis of p53 mutations in squamous cell carcinomas of hairless mice

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Skin cancer and solar UV radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Frequent clones of p53-mutated keratinocytes in normal human skin

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Two distinct p53 immunohistochemical patterns in human squamous-cell skin cancer, precursors and normal epidermis

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Ras gene mutation and amplification in human nonmelanoma skin cancers

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Codon 12 Harvey-ras mutations are rare events in non-melanoma human skin cancer

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

High levels of patched gene mutations in basal-cell carcinomas from patients with xeroderma pigmentosum

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

UV mutation signature in tumor suppressor genes involved in skin carcinogenesis in xeroderma pigmentosum patients

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

UV-specific mutations of the human patched gene in basal cell carcinomas from normal individuals and xeroderma pigmentosum patients

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Gli proteins and Hedgehog signaling: development and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Sonic hedgehog opposes epithelial cell cycle arrest

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Characterization and histogenesis of tumors in the hairless mouse produced by low-dosage incremental ultraviolet radiation

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Basal cell carcinomas in mice overexpressing sonic hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Activating Smoothened mutations in sporadic basal-cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Altered neural cell fates and medulloblastoma in mouse patched mutants

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

A cell cycle regulator potentially involved in genesis of many tumor types

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

p14ARF links the tumour suppressors RB and p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

The INK4A/ARF locus and its two gene products

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Prevalence of germ-line mutations in p16, p19ARF, and CDK4 in familial melanoma: analysis of a clinic-based population

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

p16INK4a expression is frequently decreased and associated with 9p21 loss of heterozygosity in sporadic melanoma

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Genetic alterations of p16INK4a and p53 genes in sporadic dysplastic nevus

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Mutation of the CDKN2A 5' UTR creates an aberrant initiation codon and predisposes to melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

N-ras mutations in human cutaneous melanoma from sun-exposed body sites.

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Novel putative receptor tyrosine kinase encoded by the melanoma-inducing Tu locus in Xiphophorus.

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Localization of a CDKN2 gene in linkage group V of Xiphophorus fishes defines it as a candidate for the DIFF tumor suppressor.

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

Animal model for ultraviolet radiation-induced melanoma: platyfish-swordtail hybrid

1 reference

https://api.crossref.org/works/10.1016%2FS1011-1344%2801%2900199-3

7 January 2021

10.1016/S1011-1344(01)00199-3

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

11684448