Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells. (Q33938894)

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1 March 2020

title

Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells (English)

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1 March 2020

5

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1 March 2020

Eyal Gottlieb

10

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1 March 2020

author name string

Liang Zheng

1

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1 March 2020

Elaine D MacKenzie

2

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1 March 2020

Saadia A Karim

3

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1 March 2020

Ann Hedley

4

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1 March 2020

Gabriela Kalna

6

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1 March 2020

David G Watson

7

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1 March 2020

Peter Szlosarek

8

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1 March 2020

Christian Frezza

9

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1 March 2020

publication date

21 March 2013

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1 March 2020

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1 March 2020

volume

1

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1 March 2020

page(s)

12

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1 March 2020

issue

1

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https://scigraph.springernature.com/pub.10.1186/2049-3002-1-12

1 March 2020

exact match

0 references

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Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling

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Succination of Keap1 and activation of Nrf2-dependent antioxidant pathways in FH-deficient papillary renal cell carcinoma type 2.

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Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

5 July 2018

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Reduced expression of fumarate hydratase in clear cell renal cancer mediates HIF-2α accumulation and promotes migration and invasion

5 July 2018

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Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status

5 July 2018

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Argininosuccinate lyase deficiency-argininosuccinic aciduria and beyond

5 July 2018

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5 July 2018

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p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium

5 July 2018

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UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer

5 July 2018

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The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer

5 July 2018

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Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway

5 July 2018

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Drug evaluation: ADI-PEG-20--a PEGylated arginine deiminase for arginine-auxotrophic cancers

5 July 2018

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HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Crossref

https://api.crossref.org/works/10.1186%2F2049-3002-1-12

Fumarate Hydratase Deficiency and Cancer: Activation of Hypoxia Signaling?

21 January 2018

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K‐Ras‐Driven Pancreatic Cancer Mouse Model for Anticancer Inhibitor Analyses

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24280230

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/2049-3002-1-12

1 reference

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Dimensions Publication ID

1 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24280230%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

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