CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses (Q33826217)

29 July 2017

CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses (English)

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29 July 2017

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Kayoko Maehara

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29 July 2017

Kohta Takahashi

series ordinal

2

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29 July 2017

Shigeaki Saitoh

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3

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29 July 2017

language of work or name

English

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publication date

16 February 2010

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Molecular and Cellular Biology

29 July 2017

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29 July 2017

30

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29 July 2017

2090-2104

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29 July 2017

9

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describes a project that uses

29 July 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2863584/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency

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Telomere dysfunction and tumour suppression: the senescence connection

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CENP-B controls centromere formation depending on the chromatin context

4 July 2018

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Surveillance mechanism linking Bub1 loss to the p53 pathway

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence

4 July 2018

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A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation

4 July 2018

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Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells

4 July 2018

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The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres

4 July 2018

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4 July 2018

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Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice

4 July 2018

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Centromere protein H is up-regulated in primary human colorectal cancer and its overexpression induces aneuploidy

4 July 2018

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CENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1.

4 July 2018

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4 July 2018

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Reduction of total E2F/DP activity induces senescence-like cell cycle arrest in cancer cells lacking functional pRB and p53

4 July 2018

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Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA

4 July 2018

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Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint

4 July 2018

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Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase

4 July 2018

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The serial cultivation of human diploid cell strains

4 July 2018

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Epstein-Barr virus LMP1 blocks p16INK4a-RB pathway by promoting nuclear export of E2F4/5

4 July 2018

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Overexpression and mistargeting of centromere protein-A in human primary colorectal cancer

4 July 2018

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

4 July 2018

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Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis

4 July 2018

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Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling

4 July 2018

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Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway

4 July 2018

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Fission yeast CENP-B homologs nucleate centromeric heterochromatin by promoting heterochromatin-specific histone tail modifications.

4 July 2018

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4 July 2018

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The role of Drosophila CID in kinetochore formation, cell-cycle progression and heterochromatin interactions

4 July 2018

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Differential regulation of CENP-A and histone H3 phosphorylation in G2/M.

4 July 2018

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Degradation of nucleosome-associated centromeric histone H3-like protein CENP-A induced by herpes simplex virus type 1 protein ICP0

4 July 2018

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Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

4 July 2018

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Mitotic misregulation and human aging

4 July 2018

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Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice

4 July 2018

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The cenpB gene is not essential in mice

4 July 2018

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Cse4p is a component of the core centromere of Saccharomyces cerevisiae

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863584

Centromeric protein B null mice are viable with no apparent abnormalities

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863584

Centromere protein B null mice are mitotically and meiotically normal but have lower body and testis weights

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863584

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863584

Assembly of CENP-A into centromeric chromatin requires a cooperative array of nucleosomal DNA contact sites

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863584

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863584

Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

4 July 2018

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D-type cyclin-dependent kinase activity in mammalian cells

4 July 2018

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A mutation in CSE4, an essential gene encoding a novel chromatin-associated protein in yeast, causes chromosome nondisjunction and cell cycle arrest at mitosis

4 July 2018

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

4 July 2018

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High-efficiency transformation of mammalian cells by plasmid DNA

4 July 2018

1 reference

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A 17-kD centromere protein (CENP-A) copurifies with nucleosome core particles and with histones

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863584

A human centromere antigen (CENP-B) interacts with a short specific sequence in alphoid DNA, a human centromeric satellite

4 July 2018

1 reference

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Molecular cloning of cDNA for CENP-B, the major human centromere autoantigen

4 July 2018

1 reference

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p53 mutations in human cancers

4 July 2018

1 reference

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Spindle checkpoint signaling requires the mis6 kinetochore subcomplex, which interacts with mad2 and mitotic spindles

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863584

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863584

Stable suppression of tumorigenicity by virus-mediated RNA interference

29 October 2018

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A histone-H3-like protein in C. elegans

29 October 2018

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The p16INK4a/CDKN2A tumor suppressor and its relatives.

29 October 2018

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Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20160010

12 December 2020

inferred from PubMed ID database lookup

The tumor-suppressive functions of the human INK4A locus

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20160010

12 December 2020

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Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20160010

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/MCB.01318-09

1 reference

29 July 2017

1 reference

29 July 2017

1 reference