Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli (Q33393502)

26 July 2017

title

Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli (English)

1 reference

26 July 2017

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6

Janet Rossant

1 reference

26 July 2017

António Duarte

8

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Alexandre Trindade

object named as

Alexandre Trindade

2

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Domingos Henrique

object named as

Domingos Henrique

4

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Rui Benedito

object named as

Rui Benedito

1

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author name string

Masanori Hirashima

3

1 reference

26 July 2017

Luis Lopes da Costa

5

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26 July 2017

Parkash S Gill

7

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26 July 2017

publication date

16 December 2008

1 reference

BMC Developmental Biology

26 July 2017

published in

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26 July 2017

volume

8

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26 July 2017

page(s)

117

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-213x-8-117

26 July 2017

exact match

0 references

cites work

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Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development

21 June 2018

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Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion

21 June 2018

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The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.

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21 June 2018

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Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

21 June 2018

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21 June 2018

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Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis

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Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function

21 June 2018

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Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice

21 June 2018

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Endoglin null endothelial cells proliferate faster and are more responsive to transforming growth factor beta1 with higher affinity receptors and an activated Alk1 pathway

21 June 2018

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roundabout4 is essential for angiogenesis in vivo

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

21 June 2018

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Dosage-sensitive requirement for mouse Dll4 in artery development

21 June 2018

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The VEGF receptor flt-1 (VEGFR-1) is a positive modulator of vascular sprout formation and branching morphogenesis

21 June 2018

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21 June 2018

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Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis

21 June 2018

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Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression

21 June 2018

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21 June 2018

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Notch signaling is required for arterial-venous differentiation during embryonic vascular development.

21 June 2018

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Notch signaling is essential for vascular morphogenesis in mice

21 June 2018

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Dll4, a novel Notch ligand expressed in arterial endothelium

21 June 2018

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Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development

21 June 2018

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HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments

21 June 2018

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Defective angiogenesis in mice lacking endoglin

21 June 2018

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Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1

21 June 2018

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Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

21 June 2018

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Mechanisms of angiogenesis

21 June 2018

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Neurogenic genes and vertebrate neurogenesis

21 June 2018

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A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis

21 June 2018

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Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2637862

flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors.

21 June 2018

1 reference

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Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2637862

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2637862

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2637862

Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2637862

Flow regulates arterial-venous differentiation in the chick embryo yolk sac.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2637862

sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2637862

Endoglin expression in early development is associated with vasculogenesis and angiogenesis.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2637862

Vasculogenesis in the day 6.5 to 9.5 mouse embryo.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2637862

Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2637862

Maintenance of neuroepithelial progenitor cells by Delta–Notch signalling in the embryonic chick retina

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19087347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition of endothelial cell proliferation by Notch1 signaling is mediated by repressing MAPK and PI3K/Akt pathways and requires MAML1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19087347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-213X-8-117

1 reference

Dimensions Publication ID

26 July 2017

0 references

1 reference

26 July 2017

1 reference